BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

284 related articles for article (PubMed ID: 31383852)

  • 1. DPP8/9 inhibitors are universal activators of functional NLRP1 alleles.
    Gai K; Okondo MC; Rao SD; Chui AJ; Ball DP; Johnson DC; Bachovchin DA
    Cell Death Dis; 2019 Aug; 10(8):587. PubMed ID: 31383852
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages.
    de Vasconcelos NM; Vliegen G; Gonçalves A; De Hert E; Martín-Pérez R; Van Opdenbosch N; Jallapally A; Geiss-Friedlander R; Lambeir AM; Augustyns K; Van Der Veken P; De Meester I; Lamkanfi M
    Life Sci Alliance; 2019 Feb; 2(1):. PubMed ID: 30718379
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding.
    Zhong FL; Robinson K; Teo DET; Tan KY; Lim C; Harapas CR; Yu CH; Xie WH; Sobota RM; Au VB; Hopkins R; D'Osualdo A; Reed JC; Connolly JE; Masters SL; Reversade B
    J Biol Chem; 2018 Dec; 293(49):18864-18878. PubMed ID: 30291141
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DPP8/9 inhibitors activate the CARD8 inflammasome in resting lymphocytes.
    Johnson DC; Okondo MC; Orth EL; Rao SD; Huang HC; Ball DP; Bachovchin DA
    Cell Death Dis; 2020 Aug; 11(8):628. PubMed ID: 32796818
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of the CARD8 Inflammasome Requires a Disordered Region.
    Chui AJ; Griswold AR; Taabazuing CY; Orth EL; Gai K; Rao SD; Ball DP; Hsiao JC; Bachovchin DA
    Cell Rep; 2020 Oct; 33(2):108264. PubMed ID: 33053349
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DPP9's Enzymatic Activity and Not Its Binding to CARD8 Inhibits Inflammasome Activation.
    Griswold AR; Ball DP; Bhattacharjee A; Chui AJ; Rao SD; Taabazuing CY; Bachovchin DA
    ACS Chem Biol; 2019 Nov; 14(11):2424-2429. PubMed ID: 31525884
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome.
    Okondo MC; Rao SD; Taabazuing CY; Chui AJ; Poplawski SE; Johnson DC; Bachovchin DA
    Cell Chem Biol; 2018 Mar; 25(3):262-267.e5. PubMed ID: 29396289
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The NLRP1 and CARD8 inflammasomes.
    Taabazuing CY; Griswold AR; Bachovchin DA
    Immunol Rev; 2020 Sep; 297(1):13-25. PubMed ID: 32558991
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia.
    Johnson DC; Taabazuing CY; Okondo MC; Chui AJ; Rao SD; Brown FC; Reed C; Peguero E; de Stanchina E; Kentsis A; Bachovchin DA
    Nat Med; 2018 Aug; 24(8):1151-1156. PubMed ID: 29967349
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis.
    Okondo MC; Johnson DC; Sridharan R; Go EB; Chui AJ; Wang MS; Poplawski SE; Wu W; Liu Y; Lai JH; Sanford DG; Arciprete MO; Golub TR; Bachovchin WW; Bachovchin DA
    Nat Chem Biol; 2017 Jan; 13(1):46-53. PubMed ID: 27820798
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment.
    Sharif H; Hollingsworth LR; Griswold AR; Hsiao JC; Wang Q; Bachovchin DA; Wu H
    Immunity; 2021 Jul; 54(7):1392-1404.e10. PubMed ID: 34019797
    [TBL] [Abstract][Full Text] [Related]  

  • 12. N-terminal degradation activates the NLRP1B inflammasome.
    Chui AJ; Okondo MC; Rao SD; Gai K; Griswold AR; Johnson DC; Ball DP; Taabazuing CY; Orth EL; Vittimberga BA; Bachovchin DA
    Science; 2019 Apr; 364(6435):82-85. PubMed ID: 30872531
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation.
    Hollingsworth LR; Sharif H; Griswold AR; Fontana P; Mintseris J; Dagbay KB; Paulo JA; Gygi SP; Bachovchin DA; Wu H
    Nature; 2021 Apr; 592(7856):778-783. PubMed ID: 33731932
    [TBL] [Abstract][Full Text] [Related]  

  • 14. M24B aminopeptidase inhibitors selectively activate the CARD8 inflammasome.
    Rao SD; Chen Q; Wang Q; Orth-He EL; Saoi M; Griswold AR; Bhattacharjee A; Ball DP; Huang HC; Chui AJ; Covelli DJ; You S; Cross JR; Bachovchin DA
    Nat Chem Biol; 2022 May; 18(5):565-574. PubMed ID: 35165443
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein folding stress potentiates NLRP1 and CARD8 inflammasome activation.
    Orth-He EL; Huang HC; Rao SD; Wang Q; Chen Q; O'Mara CM; Chui AJ; Saoi M; Griswold AR; Bhattacharjee A; Ball DP; Cross JR; Bachovchin DA
    Cell Rep; 2023 Jan; 42(1):111965. PubMed ID: 36649711
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes.
    Robert Hollingsworth L; David L; Li Y; Griswold AR; Ruan J; Sharif H; Fontana P; Orth-He EL; Fu TM; Bachovchin DA; Wu H
    Nat Commun; 2021 Jan; 12(1):189. PubMed ID: 33420033
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8.
    Gong Q; Robinson K; Xu C; Huynh PT; Chong KHC; Tan EYJ; Zhang J; Boo ZZ; Teo DET; Lay K; Zhang Y; Lim JSY; Goh WI; Wright G; Zhong FL; Reversade B; Wu B
    Nat Commun; 2021 Jan; 12(1):188. PubMed ID: 33420028
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The NLRP1 Inflammasome in Human Skin and Beyond.
    Fenini G; Karakaya T; Hennig P; Di Filippo M; Beer HD
    Int J Mol Sci; 2020 Jul; 21(13):. PubMed ID: 32640751
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages.
    Taabazuing CY; Okondo MC; Bachovchin DA
    Cell Chem Biol; 2017 Apr; 24(4):507-514.e4. PubMed ID: 28392147
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transcriptional analysis of the three Nlrp1 paralogs in mice.
    Sastalla I; Crown D; Masters SL; McKenzie A; Leppla SH; Moayeri M
    BMC Genomics; 2013 Mar; 14():188. PubMed ID: 23506131
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.