151 related articles for article (PubMed ID: 31386812)
1. Mechanistic and Structural Insights into Cysteine-Mediated Inhibition of Pyruvate Kinase Muscle Isoform 2.
Srivastava D; Nandi S; Dey M
Biochemistry; 2019 Sep; 58(35):3669-3682. PubMed ID: 31386812
[TBL] [Abstract][Full Text] [Related]
2. Biochemical and structural insights into how amino acids regulate pyruvate kinase muscle isoform 2.
Nandi S; Dey M
J Biol Chem; 2020 Apr; 295(16):5390-5403. PubMed ID: 32144209
[TBL] [Abstract][Full Text] [Related]
3. Structural Investigation of a Dimeric Variant of Pyruvate Kinase Muscle Isoform 2.
Srivastava D; Razzaghi M; Henzl MT; Dey M
Biochemistry; 2017 Dec; 56(50):6517-6520. PubMed ID: 29182273
[TBL] [Abstract][Full Text] [Related]
4. The cysteine residue at 424th of pyruvate kinase M2 is crucial for tetramerization and responsiveness to oxidative stress.
Masaki S; Hashimoto K; Kihara D; Tsuzuki C; Kataoka N; Suzuki K
Biochem Biophys Res Commun; 2020 Jun; 526(4):973-977. PubMed ID: 32295714
[TBL] [Abstract][Full Text] [Related]
5. Structural insight into mechanisms for dynamic regulation of PKM2.
Wang P; Sun C; Zhu T; Xu Y
Protein Cell; 2015 Apr; 6(4):275-287. PubMed ID: 25645022
[TBL] [Abstract][Full Text] [Related]
6. Pyruvate kinase M knockdown-induced signaling via AMP-activated protein kinase promotes mitochondrial biogenesis, autophagy, and cancer cell survival.
Prakasam G; Singh RK; Iqbal MA; Saini SK; Tiku AB; Bamezai RNK
J Biol Chem; 2017 Sep; 292(37):15561-15576. PubMed ID: 28778925
[TBL] [Abstract][Full Text] [Related]
7. Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation.
Chen TJ; Wang HJ; Liu JS; Cheng HH; Hsu SC; Wu MC; Lu CH; Wu YF; Wu JW; Liu YY; Kung HJ; Wang WC
Commun Biol; 2019; 2():105. PubMed ID: 30911680
[TBL] [Abstract][Full Text] [Related]
8. An engineered photoswitchable mammalian pyruvate kinase.
Gehrig S; Macpherson JA; Driscoll PC; Symon A; Martin SR; MacRae JI; Kleinjung J; Fraternali F; Anastasiou D
FEBS J; 2017 Sep; 284(18):2955-2980. PubMed ID: 28715126
[TBL] [Abstract][Full Text] [Related]
9. Cancer-associated mutations in human pyruvate kinase M2 impair enzyme activity.
Liu VM; Howell AJ; Hosios AM; Li Z; Israelsen WJ; Vander Heiden MG
FEBS Lett; 2020 Feb; 594(4):646-664. PubMed ID: 31642061
[TBL] [Abstract][Full Text] [Related]
10. Comprehensive analyses of the cysteine thiol oxidation of PKM2 reveal the effects of multiple oxidation on cellular oxidative stress response.
Irokawa H; Numasaki S; Kato S; Iwai K; Inose-Maruyama A; Ohdate T; Hwang GW; Toyama T; Watanabe T; Kuge S
Biochem J; 2021 Apr; 478(7):1453-1470. PubMed ID: 33749780
[TBL] [Abstract][Full Text] [Related]
11. L-cysteine reversibly inhibits glucose-induced biphasic insulin secretion and ATP production by inactivating PKM2.
Nakatsu D; Horiuchi Y; Kano F; Noguchi Y; Sugawara T; Takamoto I; Kubota N; Kadowaki T; Murata M
Proc Natl Acad Sci U S A; 2015 Mar; 112(10):E1067-76. PubMed ID: 25713368
[TBL] [Abstract][Full Text] [Related]
12. Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation.
Macpherson JA; Theisen A; Masino L; Fets L; Driscoll PC; Encheva V; Snijders AP; Martin SR; Kleinjung J; Barran PE; Fraternali F; Anastasiou D
Elife; 2019 Jul; 8():. PubMed ID: 31264961
[TBL] [Abstract][Full Text] [Related]
13. The Role of PKM2 in Metabolic Reprogramming: Insights into the Regulatory Roles of Non-Coding RNAs.
Puckett DL; Alquraishi M; Chowanadisai W; Bettaieb A
Int J Mol Sci; 2021 Jan; 22(3):. PubMed ID: 33503959
[TBL] [Abstract][Full Text] [Related]
14. Structural basis for allosteric regulation of pyruvate kinase M2 by phosphorylation and acetylation.
Nandi S; Razzaghi M; Srivastava D; Dey M
J Biol Chem; 2020 Dec; 295(51):17425-17440. PubMed ID: 33453989
[TBL] [Abstract][Full Text] [Related]
15. Glycolytic reprogramming in cancer cells: PKM2 dimer predominance induced by pulsatile PFK-1 activity.
Shi X; You L; Luo RY
Phys Biol; 2019 Sep; 16(6):066007. PubMed ID: 31469100
[TBL] [Abstract][Full Text] [Related]
16. Moderate DNA damage promotes metabolic flux into PPP via PKM2 Y-105 phosphorylation: a feature that favours cancer cells.
Kumar B; Bamezai RN
Mol Biol Rep; 2015 Aug; 42(8):1317-21. PubMed ID: 25840825
[TBL] [Abstract][Full Text] [Related]
17. CARM1 suppresses
Abeywardana T; Oh M; Jiang L; Yang Y; Kong M; Song J; Yang Y
J Biol Chem; 2018 Sep; 293(39):15290-15303. PubMed ID: 30131339
[TBL] [Abstract][Full Text] [Related]
18. SIRT2-Mediated Deacetylation and Tetramerization of Pyruvate Kinase Directs Glycolysis and Tumor Growth.
Park SH; Ozden O; Liu G; Song HY; Zhu Y; Yan Y; Zou X; Kang HJ; Jiang H; Principe DR; Cha YI; Roh M; Vassilopoulos A; Gius D
Cancer Res; 2016 Jul; 76(13):3802-12. PubMed ID: 27197174
[TBL] [Abstract][Full Text] [Related]
19. Targeting pyruvate kinase muscle isoform 2 (PKM2) in cancer: What do we know so far?
Chhipa AS; Patel S
Life Sci; 2021 Sep; 280():119694. PubMed ID: 34102192
[TBL] [Abstract][Full Text] [Related]
20. PKM2-dependent glycolysis promotes the proliferation and migration of vascular smooth muscle cells during atherosclerosis.
Zhao X; Tan F; Cao X; Cao Z; Li B; Shen Z; Tian Y
Acta Biochim Biophys Sin (Shanghai); 2020 Jan; 52(1):9-17. PubMed ID: 31867609
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]