350 related articles for article (PubMed ID: 31391321)
1. Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells.
Wang X; Yang K; Wu Q; Kim LJY; Morton AR; Gimple RC; Prager BC; Shi Y; Zhou W; Bhargava S; Zhu Z; Jiang L; Tao W; Qiu Z; Zhao L; Zhang G; Li X; Agnihotri S; Mischel PS; Mack SC; Bao S; Rich JN
Sci Transl Med; 2019 Aug; 11(504):. PubMed ID: 31391321
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of the de novo pyrimidine biosynthesis pathway limits ribosomal RNA transcription causing nucleolar stress in glioblastoma cells.
Lafita-Navarro MC; Venkateswaran N; Kilgore JA; Kanji S; Han J; Barnes S; Williams NS; Buszczak M; Burma S; Conacci-Sorrell M
PLoS Genet; 2020 Nov; 16(11):e1009117. PubMed ID: 33201894
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of canine distemper virus replication by blocking pyrimidine nucleotide synthesis with A77 1726, the active metabolite of the anti-inflammatory drug leflunomide.
Li Y; Yi L; Cheng S; Wang Y; Wang J; Sun J; Zhang Q; Xu X
J Gen Virol; 2021 Mar; 102(3):. PubMed ID: 33416466
[TBL] [Abstract][Full Text] [Related]
4. Discovery of a new pyrimidine synthesis inhibitor eradicating glioblastoma-initiating cells.
Echizenya S; Ishii Y; Kitazawa S; Tanaka T; Matsuda S; Watanabe E; Umekawa M; Terasaka S; Houkin K; Hatta T; Natsume T; Maeda Y; Watanabe SI; Hagiwara S; Kondo T
Neuro Oncol; 2020 Feb; 22(2):229-239. PubMed ID: 31499527
[TBL] [Abstract][Full Text] [Related]
5. Targeting of BMI-1 with PTC-209 inhibits glioblastoma development.
Kong Y; Ai C; Dong F; Xia X; Zhao X; Yang C; Kang C; Zhou Y; Zhao Q; Sun X; Wu X
Cell Cycle; 2018; 17(10):1199-1211. PubMed ID: 29886801
[TBL] [Abstract][Full Text] [Related]
6. Revisiting the role of dihydroorotate dehydrogenase as a therapeutic target for cancer.
Madak JT; Bankhead A; Cuthbertson CR; Showalter HD; Neamati N
Pharmacol Ther; 2019 Mar; 195():111-131. PubMed ID: 30347213
[TBL] [Abstract][Full Text] [Related]
7. PTEN Regulates Glutamine Flux to Pyrimidine Synthesis and Sensitivity to Dihydroorotate Dehydrogenase Inhibition.
Mathur D; Stratikopoulos E; Ozturk S; Steinbach N; Pegno S; Schoenfeld S; Yong R; Murty VV; Asara JM; Cantley LC; Parsons R
Cancer Discov; 2017 Apr; 7(4):380-390. PubMed ID: 28255082
[TBL] [Abstract][Full Text] [Related]
8. m
Cui Q; Shi H; Ye P; Li L; Qu Q; Sun G; Sun G; Lu Z; Huang Y; Yang CG; Riggs AD; He C; Shi Y
Cell Rep; 2017 Mar; 18(11):2622-2634. PubMed ID: 28297667
[TBL] [Abstract][Full Text] [Related]
9. Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects.
Klotz L; Eschborn M; Lindner M; Liebmann M; Herold M; Janoschka C; Torres Garrido B; Schulte-Mecklenbeck A; Gross CC; Breuer J; Hundehege P; Posevitz V; Pignolet B; Nebel G; Glander S; Freise N; Austermann J; Wirth T; Campbell GR; Schneider-Hohendorf T; Eveslage M; Brassat D; Schwab N; Loser K; Roth J; Busch KB; Stoll M; Mahad DJ; Meuth SG; Turner T; Bar-Or A; Wiendl H
Sci Transl Med; 2019 May; 11(490):. PubMed ID: 31043571
[TBL] [Abstract][Full Text] [Related]
10. Engagement of cellular prion protein with the co-chaperone Hsp70/90 organizing protein regulates the proliferation of glioblastoma stem-like cells.
Iglesia RP; Prado MB; Cruz L; Martins VR; Santos TG; Lopes MH
Stem Cell Res Ther; 2017 Apr; 8(1):76. PubMed ID: 28412969
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of Nucleotide Synthesis Targets Brain Tumor Stem Cells in a Subset of Glioblastoma.
Laks DR; Ta L; Crisman TJ; Gao F; Coppola G; Radu CG; Nathanson DA; Kornblum HI
Mol Cancer Ther; 2016 Jun; 15(6):1271-8. PubMed ID: 27196770
[TBL] [Abstract][Full Text] [Related]
12. EGFR signaling is differentially activated in patient-derived glioblastoma stem cells.
Howard BM; Gursel DB; Bleau AM; Beyene RT; Holland EC; Boockvar JA
J Exp Ther Oncol; 2010; 8(3):247-60. PubMed ID: 20734923
[TBL] [Abstract][Full Text] [Related]
13. Cyclin D1 extensively reprograms metabolism to support biosynthetic pathways in hepatocytes.
Wu H; Kren BT; Lane AN; Cassel TA; Higashi RM; Fan TWM; Scaria GS; Shekels LL; Klein MA; Albrecht JH
J Biol Chem; 2023 Dec; 299(12):105407. PubMed ID: 38152849
[TBL] [Abstract][Full Text] [Related]
14. Targeting atypical protein kinase C iota reduces viability in glioblastoma stem-like cells via a notch signaling mechanism.
Phillips E; Lang V; Bohlen J; Bethke F; Puccio L; Tichy D; Herold-Mende C; Hielscher T; Lichter P; Goidts V
Int J Cancer; 2016 Oct; 139(8):1776-87. PubMed ID: 27299852
[TBL] [Abstract][Full Text] [Related]
15. Glioma Stem Cell-Specific Superenhancer Promotes Polyunsaturated Fatty-Acid Synthesis to Support EGFR Signaling.
Gimple RC; Kidwell RL; Kim LJY; Sun T; Gromovsky AD; Wu Q; Wolf M; Lv D; Bhargava S; Jiang L; Prager BC; Wang X; Ye Q; Zhu Z; Zhang G; Dong Z; Zhao L; Lee D; Bi J; Sloan AE; Mischel PS; Brown JM; Cang H; Huan T; Mack SC; Xie Q; Rich JN
Cancer Discov; 2019 Sep; 9(9):1248-1267. PubMed ID: 31201181
[TBL] [Abstract][Full Text] [Related]
16. Replication and ribosomal stress induced by targeting pyrimidine synthesis and cellular checkpoints suppress p53-deficient tumors.
Hubackova S; Davidova E; Boukalova S; Kovarova J; Bajzikova M; Coelho A; Terp MG; Ditzel HJ; Rohlena J; Neuzil J
Cell Death Dis; 2020 Feb; 11(2):110. PubMed ID: 32034120
[TBL] [Abstract][Full Text] [Related]
17. DHODH inhibition impedes glioma stem cell proliferation, induces DNA damage, and prolongs survival in orthotopic glioblastoma xenografts.
Spina R; Mills I; Ahmad F; Chen C; Ames HM; Winkles JA; Woodworth GF; Bar EE
Oncogene; 2022 Dec; 41(50):5361-5372. PubMed ID: 36344676
[TBL] [Abstract][Full Text] [Related]
18. PI3K/Akt and Stat3 signaling regulated by PTEN control of the cancer stem cell population, proliferation and senescence in a glioblastoma cell line.
Moon SH; Kim DK; Cha Y; Jeon I; Song J; Park KS
Int J Oncol; 2013 Mar; 42(3):921-8. PubMed ID: 23314408
[TBL] [Abstract][Full Text] [Related]
19. Region-specific distribution of dihydroorotate dehydrogenase in the rat central nervous system points to pyrimidine de novo synthesis in neurons.
Schaefer ChM; Schäfer MK; Löfflerr M
Nucleosides Nucleotides Nucleic Acids; 2010 Jun; 29(4-6):476-81. PubMed ID: 20544541
[TBL] [Abstract][Full Text] [Related]
20. Cross-talk between PARN and EGFR-STAT3 Signaling Facilitates Self-Renewal and Proliferation of Glioblastoma Stem Cells.
Yin J; Seo Y; Rhim J; Jin X; Kim TH; Kim SS; Hong JH; Gwak HS; Yoo H; Park JB; Kim JH
Cancer Res; 2023 Nov; 83(22):3693-3709. PubMed ID: 37747775
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
