BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

275 related articles for article (PubMed ID: 31399482)

  • 1. Therapeutic targeting of Notch signaling and immune checkpoint blockade in a spontaneous, genetically heterogeneous mouse model of T-cell acute lymphoblastic leukemia.
    Gao J; Van Meter M; Hernandez Lopez S; Chen G; Huang Y; Ren S; Zhao Q; Rojas J; Gurer C; Thurston G; Kuhnert F
    Dis Model Mech; 2019 Sep; 12(9):. PubMed ID: 31399482
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Notch1 inhibition targets the leukemia-initiating cells in a Tal1/Lmo2 mouse model of T-ALL.
    Tatarek J; Cullion K; Ashworth T; Gerstein R; Aster JC; Kelliher MA
    Blood; 2011 Aug; 118(6):1579-90. PubMed ID: 21670468
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Therapeutic antibody targeting of Notch1 in T-acute lymphoblastic leukemia xenografts.
    Agnusdei V; Minuzzo S; Frasson C; Grassi A; Axelrod F; Satyal S; Gurney A; Hoey T; Seganfreddo E; Basso G; Valtorta S; Moresco RM; Amadori A; Indraccolo S
    Leukemia; 2014 Feb; 28(2):278-88. PubMed ID: 23774673
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DLL4 regulates NOTCH signaling and growth of T acute lymphoblastic leukemia cells in NOD/SCID mice.
    Minuzzo S; Agnusdei V; Pusceddu I; Pinazza M; Moserle L; Masiero M; Rossi E; Crescenzi M; Hoey T; Ponzoni M; Amadori A; Indraccolo S
    Carcinogenesis; 2015 Jan; 36(1):115-21. PubMed ID: 25355291
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition.
    Habets RA; de Bock CE; Serneels L; Lodewijckx I; Verbeke D; Nittner D; Narlawar R; Demeyer S; Dooley J; Liston A; Taghon T; Cools J; de Strooper B
    Sci Transl Med; 2019 May; 11(494):. PubMed ID: 31142678
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Murine Pten(-/-) T-ALL requires non-redundant PI3K/mTOR and DLL4/Notch1 signals for maintenance and γc/TCR signals for thymic exit.
    Hagenbeek TJ; Wu X; Choy L; Sanchez-Irizarry C; Seshagiri S; Stinson J; Siebel CW; Spits H
    Cancer Lett; 2014 May; 346(2):237-48. PubMed ID: 24384093
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia.
    Durinck K; Wallaert A; Van de Walle I; Van Loocke W; Volders PJ; Vanhauwaert S; Geerdens E; Benoit Y; Van Roy N; Poppe B; Soulier J; Cools J; Mestdagh P; Vandesompele J; Rondou P; Van Vlierberghe P; Taghon T; Speleman F
    Haematologica; 2014 Dec; 99(12):1808-16. PubMed ID: 25344525
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Recent advances on NOTCH signaling in T-ALL.
    Tzoneva G; Ferrando AA
    Curr Top Microbiol Immunol; 2012; 360():163-82. PubMed ID: 22673746
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL.
    Jeannet R; Mastio J; Macias-Garcia A; Oravecz A; Ashworth T; Geimer Le Lay AS; Jost B; Le Gras S; Ghysdael J; Gridley T; Honjo T; Radtke F; Aster JC; Chan S; Kastner P
    Blood; 2010 Dec; 116(25):5443-54. PubMed ID: 20829372
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia.
    Witkowski MT; Cimmino L; Hu Y; Trimarchi T; Tagoh H; McKenzie MD; Best SA; Tuohey L; Willson TA; Nutt SL; Busslinger M; Aifantis I; Smyth GK; Dickins RA
    Leukemia; 2015 Jun; 29(6):1301-11. PubMed ID: 25655195
    [TBL] [Abstract][Full Text] [Related]  

  • 11. New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia.
    Hales EC; Taub JW; Matherly LH
    Cell Signal; 2014 Jan; 26(1):149-61. PubMed ID: 24140475
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dissecting molecular mechanisms of resistance to NOTCH1-targeted therapy in T-cell acute lymphoblastic leukemia xenografts.
    Agnusdei V; Minuzzo S; Pinazza M; Gasparini A; Pezzè L; Amaro AA; Pasqualini L; Bianco PD; Tognon M; Frasson C; Palumbo P; Ciribilli Y; Pfeffer U; Carella M; Amadori A; Indraccolo S
    Haematologica; 2020 May; 105(5):1317-1328. PubMed ID: 31467126
    [TBL] [Abstract][Full Text] [Related]  

  • 13. High selective pressure for Notch1 mutations that induce Myc in T-cell acute lymphoblastic leukemia.
    Chiang MY; Wang Q; Gormley AC; Stein SJ; Xu L; Shestova O; Aster JC; Pear WS
    Blood; 2016 Nov; 128(18):2229-2240. PubMed ID: 27670423
    [TBL] [Abstract][Full Text] [Related]  

  • 14. IL-7R is essential for leukemia-initiating cell activity of T-cell acute lymphoblastic leukemia.
    González-García S; Mosquera M; Fuentes P; Palumbo T; Escudero A; Pérez-Martínez A; Ramírez M; Corcoran AE; Toribio ML
    Blood; 2019 Dec; 134(24):2171-2182. PubMed ID: 31530562
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia.
    Paganin M; Ferrando A
    Blood Rev; 2011 Mar; 25(2):83-90. PubMed ID: 20965628
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies.
    Bernasconi-Elias P; Hu T; Jenkins D; Firestone B; Gans S; Kurth E; Capodieci P; Deplazes-Lauber J; Petropoulos K; Thiel P; Ponsel D; Hee Choi S; LeMotte P; London A; Goetcshkes M; Nolin E; Jones MD; Slocum K; Kluk MJ; Weinstock DM; Christodoulou A; Weinberg O; Jaehrling J; Ettenberg SA; Buckler A; Blacklow SC; Aster JC; Fryer CJ
    Oncogene; 2016 Nov; 35(47):6077-6086. PubMed ID: 27157619
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MAFB enhances oncogenic Notch signaling in T cell acute lymphoblastic leukemia.
    Pajcini KV; Xu L; Shao L; Petrovic J; Palasiewicz K; Ohtani Y; Bailis W; Lee C; Wertheim GB; Mani R; Muthusamy N; Li Y; Meijerink JPP; Blacklow SC; Faryabi RB; Cherry S; Pear WS
    Sci Signal; 2017 Nov; 10(505):. PubMed ID: 29138297
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NOTCH1 signaling promotes human T-cell acute lymphoblastic leukemia initiating cell regeneration in supportive niches.
    Ma W; Gutierrez A; Goff DJ; Geron I; Sadarangani A; Jamieson CA; Court AC; Shih AY; Jiang Q; Wu CC; Li K; Smith KM; Crews LA; Gibson NW; Deichaite I; Morris SR; Wei P; Carson DA; Look AT; Jamieson CH
    PLoS One; 2012; 7(6):e39725. PubMed ID: 22768113
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Notch3-mediated regulation of MKP-1 levels promotes survival of T acute lymphoblastic leukemia cells.
    Masiero M; Minuzzo S; Pusceddu I; Moserle L; Persano L; Agnusdei V; Tosello V; Basso G; Amadori A; Indraccolo S
    Leukemia; 2011 Apr; 25(4):588-98. PubMed ID: 21263446
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NOTCH and phosphatidylinositide 3-kinase/phosphatase and tensin homolog deleted on chromosome ten/AKT/mammalian target of rapamycin (mTOR) signaling in T-cell development and T-cell acute lymphoblastic leukemia.
    Guo D; Teng Q; Ji C
    Leuk Lymphoma; 2011 Jul; 52(7):1200-10. PubMed ID: 21463127
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.