BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 31399483)

  • 1. Ligand-Free Estrogen Receptor
    Wang D; Lu R; Rempala G; Sadee W
    Mol Pharmacol; 2019 Oct; 96(4):430-440. PubMed ID: 31399483
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Co-expression of drug metabolizing cytochrome P450 enzymes and estrogen receptor alpha (ESR1) in human liver: racial differences and the regulatory role of ESR1.
    Collins JM; Wang D
    Drug Metab Pers Ther; 2021 Apr; 36(3):205-214. PubMed ID: 33823094
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Genome-wide microRNA profiles identify miR-107 as a top miRNA associating with expression of the CYP3As and other drug metabolizing cytochrome P450 enzymes in the liver.
    Tantawy M; Collins JM; Wang D
    Front Pharmacol; 2022; 13():943538. PubMed ID: 36059981
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ESR1 ChIP-Seq Identifies Distinct Ligand-Free ESR1 Genomic Binding Sites in Human Hepatocytes and Liver Tissue.
    Collins JM; Huo Z; Wang D
    Int J Mol Sci; 2021 Feb; 22(3):. PubMed ID: 33540646
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cis-acting regulatory elements regulating CYP3A4 transcription in human liver.
    Collins JM; Wang D
    Pharmacogenet Genomics; 2020 Jul; 30(5):107-116. PubMed ID: 32301865
    [TBL] [Abstract][Full Text] [Related]  

  • 6. STAT5A and STAT5B have opposite correlations with drug response gene expression.
    Lamba V; Jia B; Liang F
    Biochem Biophys Res Commun; 2016 Oct; 479(2):117-124. PubMed ID: 27264955
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transcriptional Regulation of Carboxylesterase 1 in Human Liver: Role of the Nuclear Receptor Subfamily 1 Group H Member 3 and Its Splice Isoforms.
    Collins JM; Lu R; Wang X; Zhu HJ; Wang D
    Drug Metab Dispos; 2022 Jan; 50(1):43-48. PubMed ID: 34697082
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Direct transcriptional regulation of human hepatic cytochrome P450 3A4 (CYP3A4) by peroxisome proliferator-activated receptor alpha (PPARα).
    Thomas M; Burk O; Klumpp B; Kandel BA; Damm G; Weiss TS; Klein K; Schwab M; Zanger UM
    Mol Pharmacol; 2013 Mar; 83(3):709-18. PubMed ID: 23295386
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enhanced intrinsic CYP3A4 activity in human hepatic C3A cells with optically controlled CRISPR/dCas9 activator complex.
    Han S; Wei S; Wang X; Han X; Zhang M; Su M; Li Y; Guo J; Zeng W; Liu J; Gao Y; Shen L
    Integr Biol (Camb); 2018 Dec; 10(12):780-790. PubMed ID: 30520487
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Exploration of components and mechanisms of Polygoni Multiflori Radix-induced hepatotoxicity using siRNA -mediated CYP3A4 or UGT1A1 knockdown liver cells.
    Hu YH; Li DK; Quan ZY; Wang CY; Zhou M; Sun ZX
    J Ethnopharmacol; 2021 Apr; 270():113845. PubMed ID: 33485974
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gene Expression Profiling of 1α,25(OH)
    Pavek P; Dusek J; Smutny T; Lochman L; Kucera R; Skoda J; Smutna L; Kamaraj R; Soucek P; Vrzal R; Dvorak Z
    Mol Nutr Food Res; 2022 May; 66(9):e2200070. PubMed ID: 35184385
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Estrogen-Estrogen Receptor α Signaling Facilitates Bilirubin Metabolism in Regenerating Liver Through Regulating Cytochrome P450 2A6 Expression.
    Kao TL; Chen YL; Kuan YP; Chang WC; Ho YC; Yeh S; Jeng LB; Ma WL
    Cell Transplant; 2017 Nov; 26(11):1822-1829. PubMed ID: 29338386
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inference of hierarchical regulatory network of estrogen-dependent breast cancer through ChIP-based data.
    Gu F; Hsu HK; Hsu PY; Wu J; Ma Y; Parvin J; Huang TH; Jin VX
    BMC Syst Biol; 2010 Dec; 4():170. PubMed ID: 21167036
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries.
    Utkarsh D; Loretz C; Li AP
    Chem Biol Interact; 2016 Aug; 255():12-22. PubMed ID: 26718876
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of cytochrome P450 3A4 by small vault RNAb derived from the non-coding vault RNA1 of multidrug resistance-linked vault particle.
    Meng C; Wei Z; Zhang Y; Yan L; He H; Zhang L; Xing Q
    Mol Med Rep; 2016 Jul; 14(1):387-93. PubMed ID: 27177257
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Multisite phosphorylation of human liver cytochrome P450 3A4 enhances Its gp78- and CHIP-mediated ubiquitination: a pivotal role of its Ser-478 residue in the gp78-catalyzed reaction.
    Wang Y; Guan S; Acharya P; Liu Y; Thirumaran RK; Brandman R; Schuetz EG; Burlingame AL; Correia MA
    Mol Cell Proteomics; 2012 Feb; 11(2):M111.010132. PubMed ID: 22101235
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Puromycin-based purification of cells with high expression of the cytochrome P450 CYP3A4 gene from a patient with drug-induced liver injury (DILI).
    Miyata S; Saku N; Akiyama S; Javaregowda PK; Ite K; Takashima N; Toyoda M; Yura K; Kimura T; Nishina H; Nakazawa A; Kasahara M; Nonaka H; Kiyono T; Umezawa A
    Stem Cell Res Ther; 2022 Jan; 13(1):6. PubMed ID: 35012658
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4.
    Ma X; Cheung C; Krausz KW; Shah YM; Wang T; Idle JR; Gonzalez FJ
    Drug Metab Dispos; 2008 Dec; 36(12):2506-12. PubMed ID: 18799805
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytochrome P450 3A4 mRNA is a more reliable marker than CYP3A4 activity for detecting pregnane X receptor-activated induction of drug-metabolizing enzymes.
    Fahmi OA; Kish M; Boldt S; Obach RS
    Drug Metab Dispos; 2010 Sep; 38(9):1605-11. PubMed ID: 20566695
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The long noncoding RNA HNF1A-AS1 with dual functions in the regulation of cytochrome P450 3A4.
    Wang Y; Wang P; Wang Q; Chen S; Wang X; Zhong X; Hu W; Thorne RF; Han S; Wu M; Zhang L
    Biochem Pharmacol; 2024 Feb; 220():116016. PubMed ID: 38176619
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.