214 related articles for article (PubMed ID: 31404942)
1. Biological characterization of new inhibitors of microsomal PGE synthase-1 in preclinical models of inflammation and vascular tone.
Larsson K; Steinmetz J; Bergqvist F; Arefin S; Spahiu L; Wannberg J; Pawelzik SC; Morgenstern R; Stenberg P; Kublickiene K; Korotkova M; Jakobsson PJ
Br J Pharmacol; 2019 Dec; 176(24):4625-4638. PubMed ID: 31404942
[TBL] [Abstract][Full Text] [Related]
2. A novel mPGES-1 inhibitor alleviates inflammatory responses by downregulating PGE
Lee HH; Moon Y; Shin JS; Lee JH; Kim TW; Jang C; Park C; Lee J; Kim Y; Kim Y; Werz O; Park BY; Lee JY; Lee KT
Prostaglandins Other Lipid Mediat; 2019 Oct; 144():106347. PubMed ID: 31229523
[TBL] [Abstract][Full Text] [Related]
3. Polysubstituted Pyrimidines as mPGES-1 Inhibitors: Discovery of Potent Inhibitors of PGE
Kalčic F; Kolman V; Ajani H; Zídek Z; Janeba Z
ChemMedChem; 2020 Aug; 15(15):1398-1407. PubMed ID: 32410351
[TBL] [Abstract][Full Text] [Related]
4. Design and Development of Microsomal Prostaglandin E2 Synthase-1 Inhibitors: Challenges and Future Directions.
Koeberle A; Laufer SA; Werz O
J Med Chem; 2016 Jul; 59(13):5970-86. PubMed ID: 26791385
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of microsomal prostaglandin E-synthase-1 (mPGES-1) selectively suppresses PGE
Martin EM; Jones SL
Vet Immunol Immunopathol; 2017 Oct; 192():33-40. PubMed ID: 29042013
[TBL] [Abstract][Full Text] [Related]
6. Microsomal Prostaglandin E2 Synthase-1 as a New Macromolecular Drug Target in the Prevention of Inflammation and Cancer.
Bülbül B; Küçükgüzel İ
Anticancer Agents Med Chem; 2019; 19(10):1205-1222. PubMed ID: 30827263
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of microsomal PGE synthase-1 reduces human vascular tone by increasing PGI
Ozen G; Gomez I; Daci A; Deschildre C; Boubaya L; Teskin O; Uydeş-Doğan BS; Jakobsson PJ; Longrois D; Topal G; Norel X
Br J Pharmacol; 2017 Nov; 174(22):4087-4098. PubMed ID: 28675448
[TBL] [Abstract][Full Text] [Related]
8. Microsomal prostaglandin E
Psarra A; Nikolaou A; Kokotou MG; Limnios D; Kokotos G
Expert Opin Ther Pat; 2017 Sep; 27(9):1047-1059. PubMed ID: 28627961
[TBL] [Abstract][Full Text] [Related]
9. Identification of novel microsomal prostaglandin E
Lauro G; Manfra M; Pedatella S; Fischer K; Cantone V; Terracciano S; Bertamino A; Ostacolo C; Gomez-Monterrey I; De Nisco M; Riccio R; Novellino E; Werz O; Campiglia P; Bifulco G
Eur J Med Chem; 2017 Jan; 125():278-287. PubMed ID: 27688183
[TBL] [Abstract][Full Text] [Related]
10. Effects of microsomal prostaglandin E synthase-1 inhibition on resistance artery tone in patients with end stage kidney disease.
Steinmetz-Späh J; Arefin S; Larsson K; Jahan J; Mudrovcic N; Wennberg L; Stenvinkel P; Korotkova M; Kublickiene K; Jakobsson PJ
Br J Pharmacol; 2022 Apr; 179(7):1433-1449. PubMed ID: 34766335
[TBL] [Abstract][Full Text] [Related]
11. A Multi-step Virtual Screening Protocol for the Identification of Novel Non-acidic Microsomal Prostaglandin E
Shekfeh S; Çalışkan B; Fischer K; Yalçın T; Garscha U; Werz O; Banoglu E
ChemMedChem; 2019 Jan; 14(2):273-281. PubMed ID: 30537167
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of microsomal prostaglandin E synthase-1 facilitates liver repair after hepatic injury in mice.
Nishizawa N; Ito Y; Eshima K; Ohkubo H; Kojo K; Inoue T; Raouf J; Jakobsson PJ; Uematsu S; Akira S; Narumiya S; Watanabe M; Majima M
J Hepatol; 2018 Jul; 69(1):110-120. PubMed ID: 29458169
[TBL] [Abstract][Full Text] [Related]
13. Protective Role of mPGES-1 (Microsomal Prostaglandin E Synthase-1)-Derived PGE
Hao H; Hu S; Wan Q; Xu C; Chen H; Zhu L; Xu Z; Meng J; Breyer RM; Li N; Liu DP; FitzGerald GA; Wang M
Arterioscler Thromb Vasc Biol; 2018 May; 38(5):1115-1124. PubMed ID: 29599139
[TBL] [Abstract][Full Text] [Related]
14. Novel potent benzimidazole-based microsomal prostaglandin E
Ergül AG; Maz TG; Kretzer C; Olğaç A; Jordan PM; Çalışkan B; Werz O; Banoglu E
Eur J Med Chem; 2022 Mar; 231():114167. PubMed ID: 35152061
[TBL] [Abstract][Full Text] [Related]
15. Discovery of N-amido-phenylsulfonamide derivatives as novel microsomal prostaglandin E
Kim M; Kim G; Kang M; Ko D; Nam Y; Moon CS; Kang HM; Shin JS; Werz O; Lee KT; Lee JY
Bioorg Med Chem Lett; 2021 Jun; 41():127992. PubMed ID: 33775835
[TBL] [Abstract][Full Text] [Related]
16. Characterization of a human and murine mPGES-1 inhibitor and comparison to mPGES-1 genetic deletion in mouse models of inflammation.
Leclerc P; Idborg H; Spahiu L; Larsson C; Nekhotiaeva N; Wannberg J; Stenberg P; Korotkova M; Jakobsson PJ
Prostaglandins Other Lipid Mediat; 2013 Dec; 107():26-34. PubMed ID: 24045148
[TBL] [Abstract][Full Text] [Related]
17. Characterization of a new mPGES-1 inhibitor in rat models of inflammation.
Leclerc P; Pawelzik SC; Idborg H; Spahiu L; Larsson C; Stenberg P; Korotkova M; Jakobsson PJ
Prostaglandins Other Lipid Mediat; 2013; 102-103():1-12. PubMed ID: 23528231
[TBL] [Abstract][Full Text] [Related]
18. Discovery of 2-((2-chloro-6-fluorophenyl)amino)-N-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-7,8-dihydro-1H-[1,4]dioxino[2',3':3,4]benzo[1,2-d]imidazole-5-carboxamide as potent, selective and efficacious microsomal prostaglandin E
Muthukaman N; Deshmukh S; Sarode N; Tondlekar S; Tambe M; Pisal D; Shaikh M; Kattige VG; Honnegowda S; Karande V; Kulkarni A; Jadhav SB; Mahat MYA; Gudi GS; Khairatkar-Joshi N; Gharat LA
Bioorg Med Chem Lett; 2016 Dec; 26(24):5977-5984. PubMed ID: 27865703
[TBL] [Abstract][Full Text] [Related]
19. Microsomal Prostaglandin E Synthase-1-Derived PGE2 Inhibits Vascular Smooth Muscle Cell Calcification.
Gao C; Fu Y; Li Y; Zhang X; Zhang L; Yu F; Xu SS; Xu Q; Zhu Y; Guan Y; Wang X; Kong W
Arterioscler Thromb Vasc Biol; 2016 Jan; 36(1):108-21. PubMed ID: 26543101
[TBL] [Abstract][Full Text] [Related]
20. Discovery of benzo[g]indol-3-carboxylates as potent inhibitors of microsomal prostaglandin E(2) synthase-1.
Koeberle A; Haberl EM; Rossi A; Pergola C; Dehm F; Northoff H; Troschuetz R; Sautebin L; Werz O
Bioorg Med Chem; 2009 Dec; 17(23):7924-32. PubMed ID: 19884011
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]