BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 31408809)

  • 1. Synthesis and evaluation of 2-carboxy indole derivatives as potent and selective anti-leukemic agents.
    Cury NM; Capitão RM; Almeida RDCB; Artico LL; Corrêa JR; Simão Dos Santos EF; Yunes JA; Correia CRD
    Eur J Med Chem; 2019 Nov; 181():111570. PubMed ID: 31408809
    [TBL] [Abstract][Full Text] [Related]  

  • 2. N-(1'-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: Synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia.
    Salum LB; Mascarello A; Canevarolo RR; Altei WF; Laranjeira AB; Neuenfeldt PD; Stumpf TR; Chiaradia-Delatorre LD; Vollmer LL; Daghestani HN; de Souza Melo CP; Silveira AB; Leal PC; Frederico MJ; do Nascimento LF; Santos AR; Andricopulo AD; Day BW; Yunes RA; Vogt A; Yunes JA; Nunes RJ
    Eur J Med Chem; 2015; 96():504-18. PubMed ID: 25951294
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach.
    Preti D; Romagnoli R; Rondanin R; Cacciari B; Hamel E; Balzarini J; Liekens S; Schols D; Estévez-Sarmiento F; Quintana J; Estévez F
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):1225-1238. PubMed ID: 30141353
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antitumor effects of synthetic 6,7-annulated-4-substituted indole compounds in L1210 leukemic cells in vitro.
    Perchellet JP; Waters AM; Perchellet EM; Thornton PD; Brown N; Hill D; Neuenswander B; Lushington GH; Santini C; Chandrasoma N; Buszek KR
    Anticancer Res; 2012 Nov; 32(11):4671-84. PubMed ID: 23155229
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, and biological evaluation of cyclic-indole derivatives as anti-tumor agents via the inhibition of tubulin polymerization.
    Yan J; Hu J; An B; Huang L; Li X
    Eur J Med Chem; 2017 Jan; 125():663-675. PubMed ID: 27721152
    [TBL] [Abstract][Full Text] [Related]  

  • 6. rRNA synthesis inhibitor, CX-5461, activates ATM/ATR pathway in acute lymphoblastic leukemia, arrests cells in G2 phase and induces apoptosis.
    Negi SS; Brown P
    Oncotarget; 2015 Jul; 6(20):18094-104. PubMed ID: 26061708
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel nicotinoyl pyrazoline derivates bearing N-methyl indole moiety as antitumor agents: Design, synthesis and evaluation.
    Chen K; Zhang YL; Fan J; Ma X; Qin YJ; Zhu HL
    Eur J Med Chem; 2018 Aug; 156():722-737. PubMed ID: 30041136
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SB225002 Induces Cell Death and Cell Cycle Arrest in Acute Lymphoblastic Leukemia Cells through the Activation of GLIPR1.
    de Vasconcellos JF; Laranjeira AB; Leal PC; Bhasin MK; Zenatti PP; Nunes RJ; Yunes RA; Nowill AE; Libermann TA; Zerbini LF; Yunes JA
    PLoS One; 2015; 10(8):e0134783. PubMed ID: 26302043
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Anti-leukemia effects of the novel synthetic 1-benzylindole derivative 21-900 in vitro and in vivo.
    HuangFu WC; Chao MW; Cheng CC; Wei YC; Wu YW; Liou JP; Hsiao G; Lee YC; Yang CR
    Sci Rep; 2017 Feb; 7():42291. PubMed ID: 28181578
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and structure-activity relationship of mono-indole-, bis-indole-, and tris-indole-based sulfonamides as potential anticancer agents.
    Pingaew R; Prachayasittikul S; Ruchirawat S; Prachayasittikul V
    Mol Divers; 2013 Aug; 17(3):595-604. PubMed ID: 23813045
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sodium orthovanadate inhibits growth of acute leukemia HL60 cells and HL60/A cells in vitro.
    Zhang L; Wei N; Guan G; Song T; Xu Y; Wang S; Zhou J
    Biosci Rep; 2020 Sep; 40(9):. PubMed ID: 32940655
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Unconventional Knoevenagel-type indoles: Synthesis and cell-based studies for the identification of pro-apoptotic agents.
    Spallarossa A; Caneva C; Caviglia M; Alfei S; Butini S; Campiani G; Gemma S; Brindisi M; Zisterer DM; Bright SA; Williams CD; Crespan E; Maga G; Sanna G; Delogu I; Collu G; Loddo R
    Eur J Med Chem; 2015 Sep; 102():648-60. PubMed ID: 26320088
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and Biological Evaluation of 1-Methyl-1H-indole-Pyrazoline Hybrids as Potential Tubulin Polymerization Inhibitors.
    Zhang YL; Qin YJ; Tang DJ; Yang MR; Li BY; Wang YT; Cai HY; Wang BZ; Zhu HL
    ChemMedChem; 2016 Jul; 11(13):1446-58. PubMed ID: 27159418
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, structure-activity relationship studies and biological evaluation of novel 2,5-disubstituted indole derivatives as anticancer agents.
    Hu H; Wu J; Ao M; Wang H; Zhou T; Xue Y; Qiu Y; Fang M; Wu Z
    Chem Biol Drug Des; 2016 Nov; 88(5):766-778. PubMed ID: 27315790
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The anti-tumor activity of Antrodia salmonea in human promyelocytic leukemia (HL-60) cells is mediated via the induction of G₁ cell-cycle arrest and apoptosis in vitro or in vivo.
    Hseu YC; Lee CC; Chen YC; Kumar KJ; Chen CS; Huang YC; Hsu LS; Huang HC; Yang HL
    J Ethnopharmacol; 2014 Apr; 153(2):499-510. PubMed ID: 24631961
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and in vitro cytotoxic evaluation of N-substituted benzo[5,6]cycloheptal[b]indoles.
    Joseph B; Alagille D; Mérour JY; Léonce S
    Chem Pharm Bull (Tokyo); 2000 Dec; 48(12):1872-6. PubMed ID: 11145134
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and antitumor activity of novel 2-substituted indoline imidazolium salt derivatives.
    Xu XL; Yu CL; Chen W; Li YC; Yang LJ; Li Y; Zhang HB; Yang XD
    Org Biomol Chem; 2015 Feb; 13(5):1550-7. PubMed ID: 25491254
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Substitution at the indole 3 position yields highly potent indolecombretastatins against human tumor cells.
    Álvarez R; Gajate C; Puebla P; Mollinedo F; Medarde M; Peláez R
    Eur J Med Chem; 2018 Oct; 158():167-183. PubMed ID: 30216850
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of indole-2-carbohydrazides and thiazolidinyl-indole-2-carboxamides as potent tubulin polymerization inhibitors.
    Kazan F; Yagci ZB; Bai R; Ozkirimli E; Hamel E; Ozkirimli S
    Comput Biol Chem; 2019 Jun; 80():512-523. PubMed ID: 31185422
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 2-Hydroxypropyl-β-Cyclodextrin Acts as a Novel Anticancer Agent.
    Yokoo M; Kubota Y; Motoyama K; Higashi T; Taniyoshi M; Tokumaru H; Nishiyama R; Tabe Y; Mochinaga S; Sato A; Sueoka-Aragane N; Sueoka E; Arima H; Irie T; Kimura S
    PLoS One; 2015; 10(11):e0141946. PubMed ID: 26535909
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.