BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

689 related articles for article (PubMed ID: 31409188)

  • 1. Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation.
    Stratton MS; Bagchi RA; Felisbino MB; Hirsch RA; Smith HE; Riching AS; Enyart BY; Koch KA; Cavasin MA; Alexanian M; Song K; Qi J; Lemieux ME; Srivastava D; Lam MPY; Haldar SM; Lin CY; McKinsey TA
    Circ Res; 2019 Sep; 125(7):662-677. PubMed ID: 31409188
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Brd4 inhibition attenuates unilateral ureteral obstruction-induced fibrosis by blocking TGF-β-mediated Nox4 expression.
    Zhou B; Mu J; Gong Y; Lu C; Zhao Y; He T; Qin Z
    Redox Biol; 2017 Apr; 11():390-402. PubMed ID: 28063381
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of BRD4 attenuates transverse aortic constriction- and TGF-β-induced endothelial-mesenchymal transition and cardiac fibrosis.
    Song S; Liu L; Yu Y; Zhang R; Li Y; Cao W; Xiao Y; Fang G; Li Z; Wang X; Wang Q; Zhao X; Chen L; Wang Y; Wang Q
    J Mol Cell Cardiol; 2019 Feb; 127():83-96. PubMed ID: 30529267
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SKI activates the Hippo pathway via LIMD1 to inhibit cardiac fibroblast activation.
    Landry NM; Rattan SG; Filomeno KL; Meier TW; Meier SC; Foran SJ; Meier CF; Koleini N; Fandrich RR; Kardami E; Duhamel TA; Dixon IMC
    Basic Res Cardiol; 2021 Apr; 116(1):25. PubMed ID: 33847835
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cardiac Fibroblast-Specific Activating Transcription Factor 3 Protects Against Heart Failure by Suppressing MAP2K3-p38 Signaling.
    Li Y; Li Z; Zhang C; Li P; Wu Y; Wang C; Bond Lau W; Ma XL; Du J
    Circulation; 2017 May; 135(21):2041-2057. PubMed ID: 28249877
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Infarct Collagen Topography Regulates Fibroblast Fate via p38-Yes-Associated Protein Transcriptional Enhanced Associate Domain Signals.
    Bugg D; Bretherton R; Kim P; Olszewski E; Nagle A; Schumacher AE; Chu N; Gunaje J; DeForest CA; Stevens K; Kim DH; Davis J
    Circ Res; 2020 Oct; 127(10):1306-1322. PubMed ID: 32883176
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Fibroblast-Specific Genetic Manipulation of p38 Mitogen-Activated Protein Kinase In Vivo Reveals Its Central Regulatory Role in Fibrosis.
    Molkentin JD; Bugg D; Ghearing N; Dorn LE; Kim P; Sargent MA; Gunaje J; Otsu K; Davis J
    Circulation; 2017 Aug; 136(6):549-561. PubMed ID: 28356446
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Featured Article: TGF-β1 dominates extracellular matrix rigidity for inducing differentiation of human cardiac fibroblasts to myofibroblasts.
    Cho N; Razipour SE; McCain ML
    Exp Biol Med (Maywood); 2018 Apr; 243(7):601-612. PubMed ID: 29504479
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Glutamyl-Prolyl-tRNA Synthetase Regulates Proline-Rich Pro-Fibrotic Protein Synthesis During Cardiac Fibrosis.
    Wu J; Subbaiah KCV; Xie LH; Jiang F; Khor ES; Mickelsen D; Myers JR; Tang WHW; Yao P
    Circ Res; 2020 Aug; 127(6):827-846. PubMed ID: 32611237
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Coordinate activities of BRD4 and CDK9 in the transcriptional elongation complex are required for TGFβ-induced Nox4 expression and myofibroblast transdifferentiation.
    Ijaz T; Jamaluddin M; Zhao Y; Zhang Y; Jay J; Finnerty CC; Herndon DN; Tilton RG; Brasier AR
    Cell Death Dis; 2017 Feb; 8(2):e2606. PubMed ID: 28182006
    [TBL] [Abstract][Full Text] [Related]  

  • 11. BRD4 is a novel therapeutic target for liver fibrosis.
    Ding N; Hah N; Yu RT; Sherman MH; Benner C; Leblanc M; He M; Liddle C; Downes M; Evans RM
    Proc Natl Acad Sci U S A; 2015 Dec; 112(51):15713-8. PubMed ID: 26644586
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Angiotensin II increases periostin expression via Ras/p38 MAPK/CREB and ERK1/2/TGF-β1 pathways in cardiac fibroblasts.
    Li L; Fan D; Wang C; Wang JY; Cui XB; Wu D; Zhou Y; Wu LL
    Cardiovasc Res; 2011 Jul; 91(1):80-9. PubMed ID: 21367774
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BRD4 (Bromodomain-Containing Protein 4) Interacts with GATA4 (GATA Binding Protein 4) to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes.
    Padmanabhan A; Alexanian M; Linares-Saldana R; González-Terán B; Andreoletti G; Huang Y; Connolly AJ; Kim W; Hsu A; Duan Q; Winchester SAB; Felix F; Perez-Bermejo JA; Wang Q; Li L; Shah PP; Haldar SM; Jain R; Srivastava D
    Circulation; 2020 Dec; 142(24):2338-2355. PubMed ID: 33094644
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Disruption of BRD4 at H3K27Ac-enriched enhancer region correlates with decreased c-Myc expression in Merkel cell carcinoma.
    Sengupta D; Kannan A; Kern M; Moreno MA; Vural E; Stack B; Suen JY; Tackett AJ; Gao L
    Epigenetics; 2015; 10(6):460-6. PubMed ID: 25941994
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Affinity map of bromodomain protein 4 (BRD4) interactions with the histone H4 tail and the small molecule inhibitor JQ1.
    Jung M; Philpott M; Müller S; Schulze J; Badock V; Eberspächer U; Moosmayer D; Bader B; Schmees N; Fernández-Montalván A; Haendler B
    J Biol Chem; 2014 Mar; 289(13):9304-19. PubMed ID: 24497639
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bromodomain and Extraterminal (BET) Protein Inhibition Restores Redox Balance and Inhibits Myofibroblast Activation.
    Stock CJW; Michaeloudes C; Leoni P; Durham AL; Mumby S; Wells AU; Chung KF; Adcock IM; Renzoni EA; Lindahl GE
    Biomed Res Int; 2019; 2019():1484736. PubMed ID: 31119153
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer.
    Shu S; Lin CY; He HH; Witwicki RM; Tabassum DP; Roberts JM; Janiszewska M; Huh SJ; Liang Y; Ryan J; Doherty E; Mohammed H; Guo H; Stover DG; Ekram MB; Brown J; D'Santos C; Krop IE; Dillon D; McKeown M; Ott C; Qi J; Ni M; Rao PK; Duarte M; Wu SY; Chiang CM; Anders L; Young RA; Winer E; Letai A; Barry WT; Carroll JS; Long H; Brown M; Liu XS; Meyer CA; Bradner JE; Polyak K
    Nature; 2016 Jan; 529(7586):413-417. PubMed ID: 26735014
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis.
    Tian L; Wu D; Dasgupta A; Chen KH; Mewburn J; Potus F; Lima PDA; Hong Z; Zhao YY; Hindmarch CCT; Kutty S; Provencher S; Bonnet S; Sutendra G; Archer SL
    Circ Res; 2020 Jun; 126(12):1723-1745. PubMed ID: 32216531
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BET bromodomain inhibition suppresses innate inflammatory and profibrotic transcriptional networks in heart failure.
    Duan Q; McMahon S; Anand P; Shah H; Thomas S; Salunga HT; Huang Y; Zhang R; Sahadevan A; Lemieux ME; Brown JD; Srivastava D; Bradner JE; McKinsey TA; Haldar SM
    Sci Transl Med; 2017 May; 9(390):. PubMed ID: 28515341
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Epigenetic Reader BRD4 (Bromodomain-Containing Protein 4) Governs Nucleus-Encoded Mitochondrial Transcriptome to Regulate Cardiac Function.
    Kim SY; Zhang X; Schiattarella GG; Altamirano F; Ramos TAR; French KM; Jiang N; Szweda PA; Evers BM; May HI; Luo X; Li H; Szweda LI; Maracaja-Coutinho V; Lavandero S; Gillette TG; Hill JA
    Circulation; 2020 Dec; 142(24):2356-2370. PubMed ID: 33113340
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 35.