BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 31409554)

  • 1. The isothiocyanate sulforaphane inhibits mTOR in an NRF2-independent manner.
    Zhang Y; Gilmour A; Ahn YH; de la Vega L; Dinkova-Kostova AT
    Phytomedicine; 2021 Jun; 86():153062. PubMed ID: 31409554
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sulforaphane inhibits platelet-derived growth factor-induced vascular smooth muscle cell proliferation by targeting mTOR/p70S6kinase signaling independent of Nrf2 activation.
    Shawky NM; Segar L
    Pharmacol Res; 2017 May; 119():251-264. PubMed ID: 28212891
    [TBL] [Abstract][Full Text] [Related]  

  • 3. mTOR inhibitor PP242 increases antitumor activity of sulforaphane by blocking Akt/mTOR pathway in esophageal squamous cell carcinoma.
    Lu Z; Zhang Y; Xu Y; Wei H; Zhao W; Wang P; Li Y; Hou G
    Mol Biol Rep; 2022 Jan; 49(1):451-461. PubMed ID: 34731371
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sulforaphane Activates a lysosome-dependent transcriptional program to mitigate oxidative stress.
    Li D; Shao R; Wang N; Zhou N; Du K; Shi J; Wang Y; Zhao Z; Ye X; Zhang X; Xu H
    Autophagy; 2021 Apr; 17(4):872-887. PubMed ID: 32138578
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The protective effect of sulforaphane against oxidative stress in granulosa cells of patients with polycystic ovary syndrome (PCOS) through activation of AMPK/AKT/NRF2 signaling pathway.
    Taheri M; Hayati Roudbari N; Amidi F; Parivar K
    Reprod Biol; 2021 Dec; 21(4):100563. PubMed ID: 34678578
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sulforaphane Attenuates H₂O₂-induced Oxidant Stress in Human Trabecular Meshwork Cells (HTMCs) via the Phosphatidylinositol 3-Kinase (PI3K)/Serine/Threonine Kinase (Akt)-Mediated Factor-E2-Related Factor 2 (Nrf2) Signaling Activation.
    Liu Y; Liu P; Wang Q; Sun F; Liu F
    Med Sci Monit; 2019 Jan; 25():811-818. PubMed ID: 30689624
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Isothiocyanate Sulforaphane Depends on the Nrf2/γ-GCL/GSH Axis to Prevent Mitochondrial Dysfunction in Cells Exposed to Methylglyoxal.
    Brasil FB; Gobbo RCB; de Almeida FJS; Luckachaki MD; Dos Santos Petry F; de Oliveira MR
    Neurochem Res; 2021 Apr; 46(4):740-754. PubMed ID: 33392911
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sulforaphane inhibits the production of Aβ partially through the activation of Nrf2-regulated oxidative stress.
    Zhang S; Zhao J; Bai Z; Luo L; Wu F; Li B; Shan Y
    Food Funct; 2021 Nov; 12(22):11482-11490. PubMed ID: 34699582
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sulforaphane potentially attenuates arsenic-induced nephrotoxicity via the PI3K/Akt/Nrf2 pathway in albino Wistar rats.
    Thangapandiyan S; Ramesh M; Miltonprabu S; Hema T; Jothi GB; Nandhini V
    Environ Sci Pollut Res Int; 2019 Apr; 26(12):12247-12263. PubMed ID: 30835071
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sulforaphane Potentially Ameliorates Arsenic Induced Hepatotoxicity in Albino Wistar Rats: Implication of PI3K/Akt/Nrf2 Signaling Pathway.
    Thangapandiyan S; Ramesh M; Hema T; Miltonprabu S; Uddin MS; Nandhini V; Bavithra Jothi G
    Cell Physiol Biochem; 2019; 52(5):1203-1222. PubMed ID: 31001960
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Benzyl sulforaphane is superior to sulforaphane in inhibiting the Akt/MAPK and activating the Nrf2/ARE signalling pathways in HepG2 cells.
    Ren J; Yuan L; Wang Y; Chen G; Hu K
    J Pharm Pharmacol; 2018 Dec; 70(12):1643-1653. PubMed ID: 30251384
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chronic Sulforaphane Administration Inhibits Resistance to the mTOR-Inhibitor Everolimus in Bladder Cancer Cells.
    Justin S; Rutz J; Maxeiner S; Chun FK; Juengel E; Blaheta RA
    Int J Mol Sci; 2020 Jun; 21(11):. PubMed ID: 32512849
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sulforaphane inhibits blue light-induced inflammation and apoptosis by upregulating the SIRT1/PGC-1α/Nrf2 pathway and autophagy in retinal pigment epithelial cells.
    Yang PM; Cheng KC; Huang JY; Wang SY; Lin YN; Tseng YT; Hsieh CW; Wung BS
    Toxicol Appl Pharmacol; 2021 Jun; 421():115545. PubMed ID: 33894213
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Inhibitory Effect of Sulforaphane on Bladder Cancer Cell Depends on GSH Depletion-Induced by Nrf2 Translocation.
    He C; Buongiorno LP; Wang W; Tang JCY; Miceli N; Taviano MF; Shan Y; Bao Y
    Molecules; 2021 Aug; 26(16):. PubMed ID: 34443505
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Investigating the effect of Sulforaphane on AMPK/AKT/NRF2 pathway in human granulosa-lutein cells under H
    Taheri M; Roudbari NH; Amidi F; Parivar K
    Eur J Obstet Gynecol Reprod Biol; 2022 Sep; 276():125-133. PubMed ID: 35882072
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sulforaphane prevents type 2 diabetes-induced nephropathy via AMPK-mediated activation of lipid metabolic pathways and Nrf2 antioxidative function.
    Li Z; Guo H; Li J; Ma T; Zhou S; Zhang Z; Miao L; Cai L
    Clin Sci (Lond); 2020 Sep; 134(18):2469-2487. PubMed ID: 32940670
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition.
    Breuleux M; Klopfenstein M; Stephan C; Doughty CA; Barys L; Maira SM; Kwiatkowski D; Lane HA
    Mol Cancer Ther; 2009 Apr; 8(4):742-53. PubMed ID: 19372546
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The phytoprotective agent sulforaphane prevents inflammatory degenerative diseases and age-related pathologies via Nrf2-mediated hormesis.
    Calabrese EJ; Kozumbo WJ
    Pharmacol Res; 2021 Jan; 163():105283. PubMed ID: 33160067
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sulforaphane ameliorate Arsenic induced cardiotoxicity in rats: Role of PI3k/Akt mediated Nrf2 signaling pathway.
    Thangapandiyan S; Hema T; Miltonprabu S; Paulpandi M; Dutta U
    J Biochem Mol Toxicol; 2024 Jan; 38(1):e23576. PubMed ID: 37906532
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway.
    Petkovic M; Leal EC; Alves I; Bose C; Palade PT; Singh P; Awasthi S; Børsheim E; Dalgaard LT; Singh SP; Carvalho E
    J Nutr Biochem; 2021 Dec; 98():108817. PubMed ID: 34271100
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.