These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
23. Targeting RNA polymerase I transcription machinery in cancer cells by a novel monofunctional platinum-based agent. Zhang ZL; Zhao CL; Chen Q; Xu K; Qiao X; Xu JY Eur J Med Chem; 2018 Jul; 155():434-444. PubMed ID: 29908438 [TBL] [Abstract][Full Text] [Related]
24. The nucleolus as a fundamental regulator of the p53 response and a new target for cancer therapy. Woods SJ; Hannan KM; Pearson RB; Hannan RD Biochim Biophys Acta; 2015 Jul; 1849(7):821-9. PubMed ID: 25464032 [TBL] [Abstract][Full Text] [Related]
25. Requirement of GTP binding for TIF-90-regulated ribosomal RNA synthesis and oncogenic activities in human colon cancer cells. Nguyen DQ; Hoang DH; Nelson M; Nigam L; Nguyen VTT; Zhang L; Pham TKT; Ho HD; Nguyen DDT; Lam TQ; Tat TT; Elhajmoussa Y; Ly QT; Pichiorri F; Pullarkat V; Zhang B; Kuo YH; Marcucci G; Nguyen LXT J Cell Physiol; 2020 Oct; 235(10):7567-7579. PubMed ID: 32159236 [TBL] [Abstract][Full Text] [Related]
26. Targeting ribosomal G-quadruplexes with naphthalene-diimides as RNA polymerase I inhibitors for colorectal cancer treatment. Sanchez-Martin V; Schneider DA; Ortiz-Gonzalez M; Soriano-Lerma A; Linde-Rodriguez A; Perez-Carrasco V; Gutierrez-Fernandez J; Cuadros M; González C; Soriano M; Garcia-Salcedo JA Cell Chem Biol; 2021 Nov; 28(11):1590-1601.e4. PubMed ID: 34166611 [TBL] [Abstract][Full Text] [Related]
27. The RNA polymerase I transcription machinery: an emerging target for the treatment of cancer. Drygin D; Rice WG; Grummt I Annu Rev Pharmacol Toxicol; 2010; 50():131-56. PubMed ID: 20055700 [TBL] [Abstract][Full Text] [Related]
28. The roles of RRP15 in nucleolar formation, ribosome biogenesis and checkpoint control in human cells. Dong Z; Zhu C; Zhan Q; Jiang W Oncotarget; 2017 Feb; 8(8):13240-13252. PubMed ID: 28099941 [TBL] [Abstract][Full Text] [Related]
29. Anticancer activity of CX-3543: a direct inhibitor of rRNA biogenesis. Drygin D; Siddiqui-Jain A; O'Brien S; Schwaebe M; Lin A; Bliesath J; Ho CB; Proffitt C; Trent K; Whitten JP; Lim JK; Von Hoff D; Anderes K; Rice WG Cancer Res; 2009 Oct; 69(19):7653-61. PubMed ID: 19738048 [TBL] [Abstract][Full Text] [Related]
30. PTEN represses RNA Polymerase I transcription by disrupting the SL1 complex. Zhang C; Comai L; Johnson DL Mol Cell Biol; 2005 Aug; 25(16):6899-911. PubMed ID: 16055704 [TBL] [Abstract][Full Text] [Related]
31. c-MYC G-quadruplex binding by the RNA polymerase I inhibitor BMH-21 and analogues revealed by a combined NMR and biochemical Approach. Musso L; Mazzini S; Rossini A; Castagnoli L; Scaglioni L; Artali R; Di Nicola M; Zunino F; Dallavalle S Biochim Biophys Acta Gen Subj; 2018 Mar; 1862(3):615-629. PubMed ID: 29229300 [TBL] [Abstract][Full Text] [Related]
32. p53 localizes to intranucleolar regions distinct from the ribosome production compartments. Krüger T; Scheer U J Cell Sci; 2010 Apr; 123(Pt 8):1203-8. PubMed ID: 20332106 [TBL] [Abstract][Full Text] [Related]
33. Regulation of RNA Polymerase I Transcription in Development, Disease, and Aging. Sharifi S; Bierhoff H Annu Rev Biochem; 2018 Jun; 87():51-73. PubMed ID: 29589958 [TBL] [Abstract][Full Text] [Related]
34. Isolation, Structure Elucidation, and Antiproliferative Activity of Butanolides and Lignan Glycosides from the Fruit of Aimaiti S; Saito Y; Fukuyoshi S; Goto M; Miyake K; Newman DJ; O'Keefe BR; Lee KH; Nakagawa-Goto K Molecules; 2019 Nov; 24(21):. PubMed ID: 31694283 [TBL] [Abstract][Full Text] [Related]
35. Ectopically expressed pNO40 suppresses ribosomal RNA synthesis by inhibiting UBF-dependent transcription activation. Lin YM; Chu PH; Ouyang P Biochem Biophys Res Commun; 2019 Aug; 516(2):381-387. PubMed ID: 31217076 [TBL] [Abstract][Full Text] [Related]
36. Novel Assay to Detect RNA Polymerase I Activity Guner G; Sirajuddin P; Zheng Q; Bai B; Brodie A; Liu H; Af Hällström T; Kulac I; Laiho M; De Marzo AM Mol Cancer Res; 2017 May; 15(5):577-584. PubMed ID: 28119429 [TBL] [Abstract][Full Text] [Related]
37. Targeting RNA-Polymerase I in Both Chemosensitive and Chemoresistant Populations in Epithelial Ovarian Cancer. Cornelison R; Dobbin ZC; Katre AA; Jeong DH; Zhang Y; Chen D; Petrova Y; Llaneza DC; Steg AD; Parsons L; Schneider DA; Landen CN Clin Cancer Res; 2017 Nov; 23(21):6529-6540. PubMed ID: 28778862 [No Abstract] [Full Text] [Related]
38. The stress-inducible transcription factor ATF4 accumulates at specific rRNA-processing nucleolar regions after proteasome inhibition. Galimberti V; Kinor N; Shav-Tal Y; Biggiogera M; Brüning A Eur J Cell Biol; 2016 Oct; 95(10):389-400. PubMed ID: 27567537 [TBL] [Abstract][Full Text] [Related]
39. Cellular sensitivity to UV-irradiation is mediated by RNA polymerase I transcription. Assfalg R; Alupei MC; Wagner M; Koch S; Gonzalez OG; Schelling A; Scharffetter-Kochanek K; Iben S PLoS One; 2017; 12(6):e0179843. PubMed ID: 28636660 [TBL] [Abstract][Full Text] [Related]
40. RNA polymerase I subunit RPA43 activates rRNA expression and cell proliferation but inhibits cell migration. Zhang Y; Pang Y; Zhang K; Song X; Gao J; Zhang S; Deng W Biochim Biophys Acta Gen Subj; 2023 Sep; 1867(9):130411. PubMed ID: 37343605 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]