571 related articles for article (PubMed ID: 31412289)
21. Discovery of polypodiside as a Keap1-dependent Nrf2 activator attenuating oxidative stress and accumulation of extracellular matrix in glomerular mesangial cells under high glucose.
Yao H; Zhang N; Zhang W; Li J; Hua H; Li Y
Bioorg Med Chem; 2020 Dec; 28(24):115833. PubMed ID: 33166928
[TBL] [Abstract][Full Text] [Related]
22. Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery.
Davies TG; Wixted WE; Coyle JE; Griffiths-Jones C; Hearn K; McMenamin R; Norton D; Rich SJ; Richardson C; Saxty G; Willems HM; Woolford AJ; Cottom JE; Kou JP; Yonchuk JG; Feldser HG; Sanchez Y; Foley JP; Bolognese BJ; Logan G; Podolin PL; Yan H; Callahan JF; Heightman TD; Kerns JK
J Med Chem; 2016 Apr; 59(8):3991-4006. PubMed ID: 27031670
[TBL] [Abstract][Full Text] [Related]
23. Discovery and Development of Kelch-like ECH-Associated Protein 1. Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction Inhibitors: Achievements, Challenges, and Future Directions.
Jiang ZY; Lu MC; You QD
J Med Chem; 2016 Dec; 59(24):10837-10858. PubMed ID: 27690435
[TBL] [Abstract][Full Text] [Related]
24. Design, Synthesis, and Structure-Activity Relationships of Indoline-Based Kelch-like ECH-Associated Protein 1-Nuclear Factor (Erythroid-Derived 2)-Like 2 (Keap1-Nrf2) Protein-Protein Interaction Inhibitors.
Zhou HS; Hu LB; Zhang H; Shan WX; Wang Y; Li X; Liu T; Zhao J; You QD; Jiang ZY
J Med Chem; 2020 Oct; 63(19):11149-11168. PubMed ID: 32902980
[TBL] [Abstract][Full Text] [Related]
25. Gallic acid, a natural polyphenol, protects against tert-butyl hydroperoxide- induced hepatotoxicity by activating ERK-Nrf2-Keap1-mediated antioxidative response.
Feng RB; Wang Y; He C; Yang Y; Wan JB
Food Chem Toxicol; 2018 Sep; 119():479-488. PubMed ID: 29066411
[TBL] [Abstract][Full Text] [Related]
26. A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity.
Tran KT; Pallesen JS; Solbak SMØ; Narayanan D; Baig A; Zang J; Aguayo-Orozco A; Carmona RMC; Garcia AD; Bach A
J Med Chem; 2019 Sep; 62(17):8028-8052. PubMed ID: 31411465
[TBL] [Abstract][Full Text] [Related]
27. Identification of novel indole derivatives acting as inhibitors of the Keap1-Nrf2 interaction.
Cosimelli B; Greco G; Laneri S; Novellino E; Sacchi A; Amendola G; Cosconati S; Bortolozzi R; Viola G
J Enzyme Inhib Med Chem; 2019 Dec; 34(1):1152-1157. PubMed ID: 31179771
[TBL] [Abstract][Full Text] [Related]
28. Discovery of disubstituted xylylene derivatives as small molecule direct inhibitors of Keap1-Nrf2 protein-protein interaction.
Abed DA; Lee S; Hu L
Bioorg Med Chem; 2020 Mar; 28(6):115343. PubMed ID: 32046917
[TBL] [Abstract][Full Text] [Related]
29. Recent Advances of Natural Polyphenols Activators for Keap1-Nrf2 Signaling Pathway.
Zhou Y; Jiang Z; Lu H; Xu Z; Tong R; Shi J; Jia G
Chem Biodivers; 2019 Nov; 16(11):e1900400. PubMed ID: 31482617
[TBL] [Abstract][Full Text] [Related]
30. Shinorine ameliorates chromium induced toxicity in zebrafish hepatocytes through the facultative activation of Nrf2-Keap1-ARE pathway.
Shaw P; Sen A; Mondal P; Dey Bhowmik A; Rath J; Chattopadhyay A
Aquat Toxicol; 2020 Nov; 228():105622. PubMed ID: 32947073
[TBL] [Abstract][Full Text] [Related]
31. Bis-Michael Acceptors as Novel Probes to Study the Keap1/Nrf2/ARE Pathway.
Deny LJ; Traboulsi H; Cantin AM; Marsault É; Richter MV; Bélanger G
J Med Chem; 2016 Oct; 59(20):9431-9442. PubMed ID: 27682717
[TBL] [Abstract][Full Text] [Related]
32. Novel diterpenoid-type activators of the Keap1/Nrf2/ARE signaling pathway and their regulation of redox homeostasis.
Li AL; Shen T; Wang T; Zhou MX; Wang B; Song JT; Zhang PL; Wang XL; Ren DM; Lou HX; Wang XN
Free Radic Biol Med; 2019 Sep; 141():21-33. PubMed ID: 31167117
[TBL] [Abstract][Full Text] [Related]
33. Structure-based molecular hybridization design of Keap1-Nrf2 inhibitors as novel protective agents of acute lung injury.
Zhang L; Xu L; Chen H; Zhang W; Xing C; Qu Z; Yu J; Zhuang C
Eur J Med Chem; 2021 Oct; 222():113599. PubMed ID: 34119834
[TBL] [Abstract][Full Text] [Related]
34. Allantopyrone A activates Keap1-Nrf2 pathway and protects PC12 cells from oxidative stress-induced cell death.
Uesugi S; Muroi M; Kondoh Y; Shiono Y; Osada H; Kimura KI
J Antibiot (Tokyo); 2017 Apr; 70(4):429-434. PubMed ID: 27507633
[TBL] [Abstract][Full Text] [Related]
35. Pharmacological stimulation of nuclear factor (erythroid-derived 2)-like 2 translation activates antioxidant responses.
Perez-Leal O; Barrero CA; Merali S
J Biol Chem; 2017 Aug; 292(34):14108-14121. PubMed ID: 28684421
[TBL] [Abstract][Full Text] [Related]
36. Overexpression of miR-200a protects cardiomyocytes against hypoxia-induced apoptosis by modulating the kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2 signaling axis.
Sun X; Zuo H; Liu C; Yang Y
Int J Mol Med; 2016 Oct; 38(4):1303-11. PubMed ID: 27573160
[TBL] [Abstract][Full Text] [Related]
37. The principal molecular mechanisms behind the activation of Keap1/Nrf2/ARE pathway leading to neuroprotective action in Parkinson's disease.
Chakkittukandiyil A; Sajini DV; Karuppaiah A; Selvaraj D
Neurochem Int; 2022 Jun; 156():105325. PubMed ID: 35278519
[TBL] [Abstract][Full Text] [Related]
38. Investigation of Molecular Details of Keap1-Nrf2 Inhibitors Using Molecular Dynamics and Umbrella Sampling Techniques.
Londhe AM; Gadhe CG; Lim SM; Pae AN
Molecules; 2019 Nov; 24(22):. PubMed ID: 31726716
[TBL] [Abstract][Full Text] [Related]
39. The Keap1-Nrf2 protein-protein interaction: A suitable target for small molecules.
Schmoll D; Engel CK; Glombik H
Drug Discov Today Technol; 2017 Jun; 24():11-17. PubMed ID: 29233294
[TBL] [Abstract][Full Text] [Related]
40. Perfluoroarene-based peptide macrocycles that inhibit the Nrf2/Keap1 interaction.
Steel RJ; O'Connell MA; Searcey M
Bioorg Med Chem Lett; 2018 Sep; 28(16):2728-2731. PubMed ID: 29534931
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
