269 related articles for article (PubMed ID: 31413178)
1. Antitumor Activity and Mechanistic Characterization of APE1/Ref-1 Inhibitors in Bladder Cancer.
Fishel ML; Xia H; McGeown J; McIlwain DW; Elbanna M; Craft AA; Kaimakliotis HZ; Sandusky GE; Zhang C; Pili R; Kelley MR; Jerde TJ
Mol Cancer Ther; 2019 Nov; 18(11):1947-1960. PubMed ID: 31413178
[TBL] [Abstract][Full Text] [Related]
2. APE1/Ref-1 regulates STAT3 transcriptional activity and APE1/Ref-1-STAT3 dual-targeting effectively inhibits pancreatic cancer cell survival.
Cardoso AA; Jiang Y; Luo M; Reed AM; Shahda S; He Y; Maitra A; Kelley MR; Fishel ML
PLoS One; 2012; 7(10):e47462. PubMed ID: 23094050
[TBL] [Abstract][Full Text] [Related]
3. Ref-1/APE1 as a Transcriptional Regulator and Novel Therapeutic Target in Pediatric T-cell Leukemia.
Ding J; Fishel ML; Reed AM; McAdams E; Czader MB; Cardoso AA; Kelley MR
Mol Cancer Ther; 2017 Jul; 16(7):1401-1411. PubMed ID: 28446640
[TBL] [Abstract][Full Text] [Related]
4. Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth.
Fishel ML; Jiang Y; Rajeshkumar NV; Scandura G; Sinn AL; He Y; Shen C; Jones DR; Pollok KE; Ivan M; Maitra A; Kelley MR
Mol Cancer Ther; 2011 Sep; 10(9):1698-708. PubMed ID: 21700832
[TBL] [Abstract][Full Text] [Related]
5. Ape1 regulates WNT/β-catenin signaling through its redox functional domain in pancreatic cancer cells.
Jiang S; Zhu L; Tang H; Zhang M; Chen Z; Fei J; Han B; Zou GM
Int J Oncol; 2015 Aug; 47(2):610-20. PubMed ID: 26081414
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of the redox function of APE1/Ref-1 in myeloid leukemia cell lines results in a hypersensitive response to retinoic acid-induced differentiation and apoptosis.
Fishel ML; Colvin ES; Luo M; Kelley MR; Robertson KA
Exp Hematol; 2010 Dec; 38(12):1178-88. PubMed ID: 20826193
[TBL] [Abstract][Full Text] [Related]
7. Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models.
Logsdon DP; Grimard M; Luo M; Shahda S; Jiang Y; Tong Y; Yu Z; Zyromski N; Schipani E; Carta F; Supuran CT; Korc M; Ivan M; Kelley MR; Fishel ML
Mol Cancer Ther; 2016 Nov; 15(11):2722-2732. PubMed ID: 27535970
[TBL] [Abstract][Full Text] [Related]
8. Suppression of choroidal neovascularization through inhibition of APE1/Ref-1 redox activity.
Li Y; Liu X; Zhou T; Kelley MR; Edwards PA; Gao H; Qiao X
Invest Ophthalmol Vis Sci; 2014 Jun; 55(7):4461-9. PubMed ID: 24970265
[TBL] [Abstract][Full Text] [Related]
9. Exposure of Barrett's and esophageal adenocarcinoma cells to bile acids activates EGFR-STAT3 signaling axis via induction of APE1.
Bhat AA; Lu H; Soutto M; Capobianco A; Rai P; Zaika A; El-Rifai W
Oncogene; 2018 Nov; 37(46):6011-6024. PubMed ID: 29991802
[TBL] [Abstract][Full Text] [Related]
10. Inhibitors of nuclease and redox activity of apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1).
Laev SS; Salakhutdinov NF; Lavrik OI
Bioorg Med Chem; 2017 May; 25(9):2531-2544. PubMed ID: 28161249
[TBL] [Abstract][Full Text] [Related]
11. Design and synthesis of novel quinone inhibitors targeted to the redox function of apurinic/apyrimidinic endonuclease 1/redox enhancing factor-1 (Ape1/ref-1).
Nyland RL; Luo M; Kelley MR; Borch RF
J Med Chem; 2010 Feb; 53(3):1200-10. PubMed ID: 20067291
[TBL] [Abstract][Full Text] [Related]
12. Apurinic/Apyrimidinic Endonuclease 1/Redox Factor-1 (Ape1/Ref-1) Modulates Antigen Presenting Cell-mediated T Helper Cell Type 1 Responses.
Akhter N; Takeda Y; Nara H; Araki A; Ishii N; Asao N; Asao H
J Biol Chem; 2016 Nov; 291(45):23672-23680. PubMed ID: 27637330
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of APE1/Ref-1 redox activity rescues human retinal pigment epithelial cells from oxidative stress and reduces choroidal neovascularization.
Li Y; Liu X; Zhou T; Kelley MR; Edwards P; Gao H; Qiao X
Redox Biol; 2014; 2():485-94. PubMed ID: 24624338
[TBL] [Abstract][Full Text] [Related]
14. Role of the multifunctional DNA repair and redox signaling protein Ape1/Ref-1 in cancer and endothelial cells: small-molecule inhibition of the redox function of Ape1.
Luo M; Delaplane S; Jiang A; Reed A; He Y; Fishel M; Nyland RL; Borch RF; Qiao X; Georgiadis MM; Kelley MR
Antioxid Redox Signal; 2008 Nov; 10(11):1853-67. PubMed ID: 18627350
[TBL] [Abstract][Full Text] [Related]
15. Down-regulation of apurinic/apyrimidinic endonuclease 1/redox factor-1 expression by soy isoflavones enhances prostate cancer radiotherapy in vitro and in vivo.
Raffoul JJ; Banerjee S; Singh-Gupta V; Knoll ZE; Fite A; Zhang H; Abrams J; Sarkar FH; Hillman GG
Cancer Res; 2007 Mar; 67(5):2141-9. PubMed ID: 17332344
[TBL] [Abstract][Full Text] [Related]
16. Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival.
Logsdon DP; Shah F; Carta F; Supuran CT; Kamocka M; Jacobsen MH; Sandusky GE; Kelley MR; Fishel ML
Sci Rep; 2018 Sep; 8(1):13759. PubMed ID: 30214007
[TBL] [Abstract][Full Text] [Related]
17. Functional analysis of novel analogues of E3330 that block the redox signaling activity of the multifunctional AP endonuclease/redox signaling enzyme APE1/Ref-1.
Kelley MR; Luo M; Reed A; Su D; Delaplane S; Borch RF; Nyland RL; Gross ML; Georgiadis MM
Antioxid Redox Signal; 2011 Apr; 14(8):1387-401. PubMed ID: 20874257
[TBL] [Abstract][Full Text] [Related]
18. Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE1/Ref-1) in human ovarian cancer and indentification of the therapeutic potential of APE1/Ref-1 inhibitor.
Zhang Y; Wang J; Xiang D; Wang D; Xin X
Int J Oncol; 2009 Nov; 35(5):1069-79. PubMed ID: 19787261
[TBL] [Abstract][Full Text] [Related]
19. Specific inhibition of the redox activity of ape1/ref-1 by e3330 blocks tnf-α-induced activation of IL-8 production in liver cancer cell lines.
Cesaratto L; Codarin E; Vascotto C; Leonardi A; Kelley MR; Tiribelli C; Tell G
PLoS One; 2013; 8(8):e70909. PubMed ID: 23967134
[TBL] [Abstract][Full Text] [Related]
20. Soy isoflavones augment radiation effect by inhibiting APE1/Ref-1 DNA repair activity in non-small cell lung cancer.
Singh-Gupta V; Joiner MC; Runyan L; Yunker CK; Sarkar FH; Miller S; Gadgeel SM; Konski AA; Hillman GG
J Thorac Oncol; 2011 Apr; 6(4):688-98. PubMed ID: 21325978
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
