201 related articles for article (PubMed ID: 31419740)
21. Identification of novel αβ-tubulin modulators with antiproliferative activity directed to cancer therapy using ligand and structure-based virtual screening.
Federico LB; Silva GM; de Fraga Dias A; Figueiró F; Battastini AMO; Dos Santos CBR; Costa LT; Rosa JMC; de Paula da Silva CHT
Int J Biol Macromol; 2020 Dec; 165(Pt B):3040-3050. PubMed ID: 33736292
[TBL] [Abstract][Full Text] [Related]
22. Colchicine Binding Site Agent DJ95 Overcomes Drug Resistance and Exhibits Antitumor Efficacy.
Arnst KE; Wang Y; Lei ZN; Hwang DJ; Kumar G; Ma D; Parke DN; Chen Q; Yang J; White SW; Seagroves TN; Chen ZS; Miller DD; Li W
Mol Pharmacol; 2019 Jul; 96(1):73-89. PubMed ID: 31043459
[TBL] [Abstract][Full Text] [Related]
23. The novel microtubule-destabilizing drug BAL27862 binds to the colchicine site of tubulin with distinct effects on microtubule organization.
Prota AE; Danel F; Bachmann F; Bargsten K; Buey RM; Pohlmann J; Reinelt S; Lane H; Steinmetz MO
J Mol Biol; 2014 Apr; 426(8):1848-60. PubMed ID: 24530796
[TBL] [Abstract][Full Text] [Related]
24. Design and synthesis of novel 5-(4-chlorophenyl)furan derivatives with inhibitory activity on tubulin polymerization.
Moussa SA; A Osman EE; Eid NM; Abou-Seri SM; El Moghazy SM
Future Med Chem; 2018 Aug; 10(16):1907-1924. PubMed ID: 29966433
[TBL] [Abstract][Full Text] [Related]
25. Targeting Tubulin-colchicine Site for Cancer Therapy: Inhibitors, Antibody- Drug Conjugates and Degradation Agents.
Duan Y; Liu W; Tian L; Mao Y; Song C
Curr Top Med Chem; 2019; 19(15):1289-1304. PubMed ID: 31210108
[TBL] [Abstract][Full Text] [Related]
26. The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in β-tubulin.
Yang J; Yan W; Yu Y; Wang Y; Yang T; Xue L; Yuan X; Long C; Liu Z; Chen X; Hu M; Zheng L; Qiu Q; Pei H; Li D; Wang F; Bai P; Wen J; Ye H; Chen L
J Biol Chem; 2018 Jun; 293(24):9461-9472. PubMed ID: 29691282
[TBL] [Abstract][Full Text] [Related]
27. Imidazoquinoxaline anticancer derivatives and imiquimod interact with tubulin: Characterization of molecular microtubule inhibiting mechanisms in correlation with cytotoxicity.
Courbet A; Bec N; Constant C; Larroque C; Pugniere M; El Messaoudi S; Zghaib Z; Khier S; Deleuze-Masquefa C; Gattacceca F
PLoS One; 2017; 12(8):e0182022. PubMed ID: 28797090
[TBL] [Abstract][Full Text] [Related]
28. Structural Basis of Noscapine Activation for Tubulin Binding.
Oliva MA; Prota AE; Rodríguez-Salarichs J; Bennani YL; Jiménez-Barbero J; Bargsten K; Canales Á; Steinmetz MO; Díaz JF
J Med Chem; 2020 Aug; 63(15):8495-8501. PubMed ID: 32657585
[TBL] [Abstract][Full Text] [Related]
29. Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1
Wang Q; Arnst KE; Wang Y; Kumar G; Ma D; White SW; Miller DD; Li W; Li W
J Med Chem; 2019 Jul; 62(14):6734-6750. PubMed ID: 31251599
[TBL] [Abstract][Full Text] [Related]
30. Development of a novel class of tubulin inhibitors with promising anticancer activities.
Xi J; Zhu X; Feng Y; Huang N; Luo G; Mao Y; Han X; Tian W; Wang G; Han X; Luo R; Huang Z; An J
Mol Cancer Res; 2013 Aug; 11(8):856-64. PubMed ID: 23666368
[TBL] [Abstract][Full Text] [Related]
31. Sulfamic acid promoted one-pot synthesis of phenanthrene fused-dihydrodibenzo-quinolinones: Anticancer activity, tubulin polymerization inhibition and apoptosis inducing studies.
Kumar NP; Thatikonda S; Tokala R; Kumari SS; Lakshmi UJ; Godugu C; Shankaraiah N; Kamal A
Bioorg Med Chem; 2018 May; 26(8):1996-2008. PubMed ID: 29525336
[TBL] [Abstract][Full Text] [Related]
32. Structure of a benzylidene derivative of 9(10H)-anthracenone in complex with tubulin provides a rationale for drug design.
Cheng J; Wu Y; Wang Y; Wang C; Wang Y; Wu C; Zeng S; Yu Y; Chen Q
Biochem Biophys Res Commun; 2018 Jan; 495(1):185-188. PubMed ID: 29102632
[TBL] [Abstract][Full Text] [Related]
33. Identification of novel and potent small-molecule inhibitors of tubulin with antitumor activities by virtual screening and biological evaluations.
Liu G; Jiao Y; Huang C; Chang P
J Comput Aided Mol Des; 2019 Jul; 33(7):659-664. PubMed ID: 31165955
[TBL] [Abstract][Full Text] [Related]
34. Quinolone analogue inhibits tubulin polymerization and induces apoptosis via Cdk1-involved signaling pathways.
Chen YC; Lu PH; Pan SL; Teng CM; Kuo SC; Lin TP; Ho YF; Huang YC; Guh JH
Biochem Pharmacol; 2007 Jun; 74(1):10-9. PubMed ID: 17475221
[TBL] [Abstract][Full Text] [Related]
35. Anti-mitotic activity of colchicine and the structural basis for its interaction with tubulin.
Bhattacharyya B; Panda D; Gupta S; Banerjee M
Med Res Rev; 2008 Jan; 28(1):155-83. PubMed ID: 17464966
[TBL] [Abstract][Full Text] [Related]
36. Discovery of potent microtubule-destabilizing agents targeting for colchicine site by virtual screening, biological evaluation, and molecular dynamics simulation.
Zhang H; Luo QQ; Hu ML; Wang N; Qi HZ; Zhang HR; Ding L
Eur J Pharm Sci; 2023 Jan; 180():106340. PubMed ID: 36435355
[TBL] [Abstract][Full Text] [Related]
37. Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Wang Y; Zhang H; Gigant B; Yu Y; Wu Y; Chen X; Lai Q; Yang Z; Chen Q; Yang J
FEBS J; 2016 Jan; 283(1):102-11. PubMed ID: 26462166
[TBL] [Abstract][Full Text] [Related]
38. Discovery of a Series of Acridinones as Mechanism-Based Tubulin Assembly Inhibitors with Anticancer Activity.
Magalhaes LG; Marques FB; da Fonseca MB; Rogério KR; Graebin CS; Andricopulo AD
PLoS One; 2016; 11(8):e0160842. PubMed ID: 27508497
[TBL] [Abstract][Full Text] [Related]
39. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
Romagnoli R; Kimatrai Salvador M; Schiaffino Ortega S; Baraldi PG; Oliva P; Baraldi S; Lopez-Cara LC; Brancale A; Ferla S; Hamel E; Balzarini J; Liekens S; Mattiuzzo E; Basso G; Viola G
Eur J Med Chem; 2018 Jan; 143():683-698. PubMed ID: 29220790
[TBL] [Abstract][Full Text] [Related]
40. Synthesis and biological evaluation of (1-aryl-1H-pyrazol-4-yl) (3,4,5-trimethoxyphenyl)methanone derivatives as tubulin inhibitors.
Zhai M; Wang L; Liu S; Wang L; Yan P; Wang J; Zhang J; Guo H; Guan Q; Bao K; Wu Y; Zhang W
Eur J Med Chem; 2018 Aug; 156():137-147. PubMed ID: 30006160
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]