These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 31419777)

  • 1. Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast cancer cells.
    Bozdag M; Ferraroni M; Ward C; Carta F; Bua S; Angeli A; Langdon SP; Kunkler IH; Al-Tamimi AS; Supuran CT
    Eur J Med Chem; 2019 Nov; 182():111600. PubMed ID: 31419777
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel 2-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)-1-(1,3,5-triazin-2-ylamino)guanidine derivatives: Inhibition of human carbonic anhydrase cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII, anticancer activity, and molecular modeling studies.
    Żołnowska B; Sławiński J; Szafrański K; Angeli A; Supuran CT; Kawiak A; Wieczór M; Zielińska J; Bączek T; Bartoszewska S
    Eur J Med Chem; 2018 Jan; 143():1931-1941. PubMed ID: 29146134
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX.
    Dvořanová J; Kugler M; Holub J; Šícha V; Das V; Nekvinda J; El Anwar S; Havránek M; Pospíšilová K; Fábry M; Král V; Medvedíková M; Matějková S; Lišková B; Gurská S; Džubák P; Brynda J; Hajdúch M; Grüner B; Řezáčová P
    Eur J Med Chem; 2020 Aug; 200():112460. PubMed ID: 32505851
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dual-tail arylsulfone-based benzenesulfonamides differently match the hydrophobic and hydrophilic halves of human carbonic anhydrases active sites: Selective inhibitors for the tumor-associated hCA IX isoform.
    Ibrahim HS; Allam HA; Mahmoud WR; Bonardi A; Nocentini A; Gratteri P; Ibrahim ES; Abdel-Aziz HA; Supuran CT
    Eur J Med Chem; 2018 May; 152():1-9. PubMed ID: 29684705
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel sulfonamides bearing pyrrole and pyrrolopyrimidine moieties as carbonic anhydrase inhibitors: Synthesis, cytotoxic activity and molecular modeling.
    Ghorab MM; Ceruso M; Alsaid MS; Nissan YM; Arafa RK; Supuran CT
    Eur J Med Chem; 2014 Nov; 87():186-96. PubMed ID: 25255434
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Carbonic anhydrase inhibitors. Synthesis of heterocyclic 4-substituted pyridine-3-sulfonamide derivatives and their inhibition of the human cytosolic isozymes I and II and transmembrane tumor-associated isozymes IX and XII.
    Sławiński J; Szafrański K; Vullo D; Supuran CT
    Eur J Med Chem; 2013 Nov; 69():701-10. PubMed ID: 24095761
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, carbonic anhydrase inhibition and cytotoxic activity of novel chromone-based sulfonamide derivatives.
    Awadallah FM; El-Waei TA; Hanna MM; Abbas SE; Ceruso M; Oz BE; Guler OO; Supuran CT
    Eur J Med Chem; 2015; 96():425-35. PubMed ID: 25912674
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Anti-breast cancer action of carbonic anhydrase IX inhibitor 4-[4-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-benzylidene-hydrazinocarbonyl]-benzenesulfonamide (BSM-0004):
    Mishra CB; Mongre RK; Prakash A; Jeon R; Supuran CT; Lee MS
    J Enzyme Inhib Med Chem; 2021 Dec; 36(1):954-963. PubMed ID: 33947294
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of new 2, 5-disubstituted 1,3-selenazoles as selective human carbonic anhydrase IX inhibitors with potent anti-tumor activity.
    Angeli A; Trallori E; Ferraroni M; Di Cesare Mannelli L; Ghelardini C; Supuran CT
    Eur J Med Chem; 2018 Sep; 157():1214-1222. PubMed ID: 30193219
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of 3,4-Dihydroisoquinoline-2(1H)-sulfonamides as potent carbonic anhydrase inhibitors: synthesis, biological evaluation, and enzyme--ligand X-ray studies.
    Gitto R; Agnello S; Ferro S; De Luca L; Vullo D; Brynda J; Mader P; Supuran CT; Chimirri A
    J Med Chem; 2010 Mar; 53(6):2401-8. PubMed ID: 20170095
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of 4-(thiazol-2-ylamino)-benzenesulfonamides with carbonic anhydrase I, II and IX inhibitory activity and cytotoxic effects against breast cancer cell lines.
    Abdel Gawad NM; Amin NH; Elsaadi MT; Mohamed FMM; Angeli A; De Luca V; Capasso C; Supuran CT
    Bioorg Med Chem; 2016 Jul; 24(13):3043-3051. PubMed ID: 27234893
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Anticancer effects of new dibenzenesulfonamides by inducing apoptosis and autophagy pathways and their carbonic anhydrase inhibitory effects on hCA I, hCA II, hCA IX, hCA XII isoenzymes.
    Gul HI; Yamali C; Bulbuller M; Kirmizibayrak PB; Gul M; Angeli A; Bua S; Supuran CT
    Bioorg Chem; 2018 Aug; 78():290-297. PubMed ID: 29621641
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Carbonic anhydrase inhibitors. Comparison of aliphatic sulfamate/bis-sulfamate adducts with isozymes II and IX as a platform for designing tight-binding, more isoform-selective inhibitors.
    Vitale RM; Alterio V; Innocenti A; Winum JY; Monti SM; De Simone G; Supuran CT
    J Med Chem; 2009 Oct; 52(19):5990-8. PubMed ID: 19731956
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Carbonic anhydrase inhibitors. Synthesis, and molecular structure of novel series N-substituted N'-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)guanidines and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII.
    Żołnowska B; Sławiński J; Pogorzelska A; Chojnacki J; Vullo D; Supuran CT
    Eur J Med Chem; 2014 Jan; 71():135-47. PubMed ID: 24291567
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Application of hydrazino and hydrazido linkers to connect benzenesulfonamides with hydrophilic/phobic tails for targeting the middle region of human carbonic anhydrases active site: Selective inhibitors of hCA IX.
    Allam HA; Fahim SH; F Abo-Ashour M; Nocentini A; Elbakry ME; Abdelrahman MA; Eldehna WM; Ibrahim HS; Supuran CT
    Eur J Med Chem; 2019 Oct; 179():547-556. PubMed ID: 31276899
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A new framework for novel analogues of pazopanib as potent and selective human carbonic anhydrase inhibitors: Design, repurposing rational, synthesis, crystallographic, in vivo and in vitro biological assessments.
    Hefny SM; El-Moselhy TF; El-Din N; Ammara A; Angeli A; Ferraroni M; El-Dessouki AM; Shaldam MA; Yahya G; Al-Karmalawy AA; Supuran CT; Tawfik HO
    Eur J Med Chem; 2024 Aug; 274():116527. PubMed ID: 38810335
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural investigations on coumarins leading to chromeno[4,3-c]pyrazol-4-ones and pyrano[4,3-c]pyrazol-4-ones: New scaffolds for the design of the tumor-associated carbonic anhydrase isoforms IX and XII.
    Bonardi A; Falsini M; Catarzi D; Varano F; Di Cesare Mannelli L; Tenci B; Ghelardini C; Angeli A; Supuran CT; Colotta V
    Eur J Med Chem; 2018 Feb; 146():47-59. PubMed ID: 29407972
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with effective carbonic anhydrase inhibitory activity: Solution and crystallographic investigations.
    Ivanova J; Balode A; Žalubovskis R; Leitans J; Kazaks A; Vullo D; Tars K; Supuran CT
    Bioorg Med Chem; 2017 Feb; 25(3):857-863. PubMed ID: 28024887
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of novel pyrazoline-based aromatic sulfamates with potent carbonic anhydrase isoforms II, IV and IX inhibitory efficacy.
    Nocentini A; Moi D; Balboni G; Salvadori S; Onnis V; Supuran CT
    Bioorg Chem; 2018 Apr; 77():633-639. PubMed ID: 29502024
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: solution and X-ray crystallographic studies.
    Leitans J; Sprudza A; Tanc M; Vozny I; Zalubovskis R; Tars K; Supuran CT
    Bioorg Med Chem; 2013 Sep; 21(17):5130-8. PubMed ID: 23859774
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.