These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
336 related articles for article (PubMed ID: 31420371)
1. Targeting the Mevalonate Pathway to Overcome Acquired Anti-HER2 Treatment Resistance in Breast Cancer. Sethunath V; Hu H; De Angelis C; Veeraraghavan J; Qin L; Wang N; Simon LM; Wang T; Fu X; Nardone A; Pereira R; Nanda S; Griffith OL; Tsimelzon A; Shaw C; Chamness GC; Reis-Filho JS; Weigelt B; Heiser LM; Hilsenbeck SG; Huang S; Rimawi MF; Gray JW; Osborne CK; Schiff R Mol Cancer Res; 2019 Nov; 17(11):2318-2330. PubMed ID: 31420371 [TBL] [Abstract][Full Text] [Related]
2. Dual mTORC1/2 and HER2 blockade results in antitumor activity in preclinical models of breast cancer resistant to anti-HER2 therapy. García-García C; Ibrahim YH; Serra V; Calvo MT; Guzmán M; Grueso J; Aura C; Pérez J; Jessen K; Liu Y; Rommel C; Tabernero J; Baselga J; Scaltriti M Clin Cancer Res; 2012 May; 18(9):2603-12. PubMed ID: 22407832 [TBL] [Abstract][Full Text] [Related]
3. Different mechanisms for resistance to trastuzumab versus lapatinib in HER2-positive breast cancers--role of estrogen receptor and HER2 reactivation. Wang YC; Morrison G; Gillihan R; Guo J; Ward RM; Fu X; Botero MF; Healy NA; Hilsenbeck SG; Phillips GL; Chamness GC; Rimawi MF; Osborne CK; Schiff R Breast Cancer Res; 2011; 13(6):R121. PubMed ID: 22123186 [TBL] [Abstract][Full Text] [Related]
4. β1 integrin mediates an alternative survival pathway in breast cancer cells resistant to lapatinib. Huang C; Park CC; Hilsenbeck SG; Ward R; Rimawi MF; Wang YC; Shou J; Bissell MJ; Osborne CK; Schiff R Breast Cancer Res; 2011 Aug; 13(4):R84. PubMed ID: 21884573 [TBL] [Abstract][Full Text] [Related]
5. Yes1 signaling mediates the resistance to Trastuzumab/Lap atinib in breast cancer. Takeda T; Yamamoto H; Kanzaki H; Suzawa K; Yoshioka T; Tomida S; Cui X; Murali R; Namba K; Sato H; Torigoe H; Watanabe M; Shien K; Soh J; Asano H; Tsukuda K; Kitamura Y; Miyoshi S; Sendo T; Toyooka S PLoS One; 2017; 12(2):e0171356. PubMed ID: 28158234 [TBL] [Abstract][Full Text] [Related]
6. RANK signaling increases after anti-HER2 therapy contributing to the emergence of resistance in HER2-positive breast cancer. Sanz-Moreno A; Palomeras S; Pedersen K; Morancho B; Pascual T; Galván P; Benítez S; Gomez-Miragaya J; Ciscar M; Jimenez M; Pernas S; Petit A; Soler-Monsó MT; Viñas G; Alsaleem M; Rakha EA; Green AR; Santamaria PG; Mulder C; Lemeer S; Arribas J; Prat A; Puig T; Gonzalez-Suarez E Breast Cancer Res; 2021 Mar; 23(1):42. PubMed ID: 33785053 [TBL] [Abstract][Full Text] [Related]
7. HER2-positive breast cancer cells resistant to trastuzumab and lapatinib lose reliance upon HER2 and are sensitive to the multitargeted kinase inhibitor sorafenib. Valabrega G; Capellero S; Cavalloni G; Zaccarello G; Petrelli A; Migliardi G; Milani A; Peraldo-Neia C; Gammaitoni L; Sapino A; Pecchioni C; Moggio A; Giordano S; Aglietta M; Montemurro F Breast Cancer Res Treat; 2011 Nov; 130(1):29-40. PubMed ID: 21153051 [TBL] [Abstract][Full Text] [Related]
8. Dual fatty acid synthase and HER2 signaling blockade shows marked antitumor activity against breast cancer models resistant to anti-HER2 drugs. Blancafort A; Giró-Perafita A; Oliveras G; Palomeras S; Turrado C; Campuzano Ò; Carrión-Salip D; Massaguer A; Brugada R; Palafox M; Gómez-Miragaya J; González-Suárez E; Puig T PLoS One; 2015; 10(6):e0131241. PubMed ID: 26107737 [TBL] [Abstract][Full Text] [Related]
9. Development of acquired resistance to lapatinib may sensitise HER2-positive breast cancer cells to apoptosis induction by obatoclax and TRAIL. Eustace AJ; Conlon NT; McDermott MSJ; Browne BC; O'Leary P; Holmes FA; Espina V; Liotta LA; O'Shaughnessy J; Gallagher C; O'Driscoll L; Rani S; Madden SF; O'Brien NA; Ginther C; Slamon D; Walsh N; Gallagher WM; Zagozdzon R; Watson WR; O'Donovan N; Crown J BMC Cancer; 2018 Oct; 18(1):965. PubMed ID: 30305055 [TBL] [Abstract][Full Text] [Related]
10. Dacomitinib (PF-00299804), an irreversible Pan-HER inhibitor, inhibits proliferation of HER2-amplified breast cancer cell lines resistant to trastuzumab and lapatinib. Kalous O; Conklin D; Desai AJ; O'Brien NA; Ginther C; Anderson L; Cohen DJ; Britten CD; Taylor I; Christensen JG; Slamon DJ; Finn RS Mol Cancer Ther; 2012 Sep; 11(9):1978-87. PubMed ID: 22761403 [TBL] [Abstract][Full Text] [Related]
11. Lapatinib induces apoptosis in trastuzumab-resistant breast cancer cells: effects on insulin-like growth factor I signaling. Nahta R; Yuan LX; Du Y; Esteva FJ Mol Cancer Ther; 2007 Feb; 6(2):667-74. PubMed ID: 17308062 [TBL] [Abstract][Full Text] [Related]
12. A preclinical evaluation of the PI3K alpha/delta dominant inhibitor BAY 80-6946 in HER2-positive breast cancer models with acquired resistance to the HER2-targeted therapies trastuzumab and lapatinib. Elster N; Cremona M; Morgan C; Toomey S; Carr A; O'Grady A; Hennessy BT; Eustace AJ Breast Cancer Res Treat; 2015 Jan; 149(2):373-83. PubMed ID: 25528022 [TBL] [Abstract][Full Text] [Related]
13. PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling. Moody SE; Schinzel AC; Singh S; Izzo F; Strickland MR; Luo L; Thomas SR; Boehm JS; Kim SY; Wang ZC; Hahn WC Oncogene; 2015 Apr; 34(16):2061-71. PubMed ID: 24909179 [TBL] [Abstract][Full Text] [Related]
15. HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2 Xu X; De Angelis C; Burke KA; Nardone A; Hu H; Qin L; Veeraraghavan J; Sethunath V; Heiser LM; Wang N; Ng CKY; Chen ES; Renwick A; Wang T; Nanda S; Shea M; Mitchell T; Rajendran M; Waters I; Zabransky DJ; Scott KL; Gutierrez C; Nagi C; Geyer FC; Chamness GC; Park BH; Shaw CA; Hilsenbeck SG; Rimawi MF; Gray JW; Weigelt B; Reis-Filho JS; Osborne CK; Schiff R Clin Cancer Res; 2017 Sep; 23(17):5123-5134. PubMed ID: 28487443 [No Abstract] [Full Text] [Related]
16. PP2A inhibition overcomes acquired resistance to HER2 targeted therapy. McDermott MS; Browne BC; Conlon NT; O'Brien NA; Slamon DJ; Henry M; Meleady P; Clynes M; Dowling P; Crown J; O'Donovan N Mol Cancer; 2014 Jun; 13():157. PubMed ID: 24958351 [TBL] [Abstract][Full Text] [Related]
17. Phosphoproteomic analysis reveals PAK2 as a therapeutic target for lapatinib resistance in HER2-positive breast cancer cells. Chang Y; Park KH; Lee JE; Han KC Biochem Biophys Res Commun; 2018 Oct; 505(1):187-193. PubMed ID: 30243723 [TBL] [Abstract][Full Text] [Related]
18. Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo. Ding X; Sharko AC; McDermott MSJ; Schools GP; Chumanevich A; Ji H; Li J; Zhang L; Mack ZT; Sikirzhytski V; Shtutman M; Ivers L; O'Donovan N; Crown J; Győrffy B; Chen M; Roninson IB; Broude EV Proc Natl Acad Sci U S A; 2022 Aug; 119(32):e2201073119. PubMed ID: 35914167 [TBL] [Abstract][Full Text] [Related]
19. A novel inhibitor of fatty acid synthase shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines. Puig T; Aguilar H; Cufí S; Oliveras G; Turrado C; Ortega-Gutiérrez S; Benhamú B; López-Rodríguez ML; Urruticoechea A; Colomer R Breast Cancer Res; 2011; 13(6):R131. PubMed ID: 22177475 [TBL] [Abstract][Full Text] [Related]
20. Receptor tyrosine kinase ERBB4 mediates acquired resistance to ERBB2 inhibitors in breast cancer cells. Canfield K; Li J; Wilkins OM; Morrison MM; Ung M; Wells W; Williams CR; Liby KT; Vullhorst D; Buonanno A; Hu H; Schiff R; Cook RS; Kurokawa M Cell Cycle; 2015; 14(4):648-55. PubMed ID: 25590338 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]