208 related articles for article (PubMed ID: 31422906)
1. Discovery and Characterization of a Cellular Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7.
Lamb KN; Bsteh D; Dishman SN; Moussa HF; Fan H; Stuckey JI; Norris JL; Cholensky SH; Li D; Wang J; Sagum C; Stanton BZ; Bedford MT; Pearce KH; Kenakin TP; Kireev DB; Wang GG; James LI; Bell O; Frye SV
Cell Chem Biol; 2019 Oct; 26(10):1365-1379.e22. PubMed ID: 31422906
[TBL] [Abstract][Full Text] [Related]
2. Reprogramming CBX8-PRC1 function with a positive allosteric modulator.
Suh JL; Bsteh D; Hart B; Si Y; Weaver TM; Pribitzer C; Lau R; Soni S; Ogana H; Rectenwald JM; Norris JL; Cholensky SH; Sagum C; Umana JD; Li D; Hardy B; Bedford MT; Mumenthaler SM; Lenz HJ; Kim YM; Wang GG; Pearce KH; James LI; Kireev DB; Musselman CA; Frye SV; Bell O
Cell Chem Biol; 2022 Apr; 29(4):555-571.e11. PubMed ID: 34715055
[TBL] [Abstract][Full Text] [Related]
3. Discovery of Peptidomimetic Ligands of EED as Allosteric Inhibitors of PRC2.
Barnash KD; The J; Norris-Drouin JL; Cholensky SH; Worley BM; Li F; Stuckey JI; Brown PJ; Vedadi M; Arrowsmith CH; Frye SV; James LI
ACS Comb Sci; 2017 Mar; 19(3):161-172. PubMed ID: 28165227
[TBL] [Abstract][Full Text] [Related]
4. Structure-Guided Discovery of Selective Antagonists for the Chromodomain of Polycomb Repressive Protein CBX7.
Ren C; Smith SG; Yap K; Li S; Li J; Mezei M; Rodriguez Y; Vincek A; Aguilo F; Walsh MJ; Zhou MM
ACS Med Chem Lett; 2016 Jun; 7(6):601-5. PubMed ID: 27326334
[TBL] [Abstract][Full Text] [Related]
5. Mitogen-activated protein kinase signaling mediates phosphorylation of polycomb ortholog Cbx7.
Wu HA; Balsbaugh JL; Chandler H; Georgilis A; Zullow H; Shabanowitz J; Hunt DF; Gil J; Peters G; Bernstein E
J Biol Chem; 2013 Dec; 288(51):36398-408. PubMed ID: 24194518
[TBL] [Abstract][Full Text] [Related]
6. Chromodomain antagonists that target the polycomb-group methyllysine reader protein chromobox homolog 7 (CBX7).
Simhadri C; Daze KD; Douglas SF; Quon TT; Dev A; Gignac MC; Peng F; Heller M; Boulanger MJ; Wulff JE; Hof F
J Med Chem; 2014 Apr; 57(7):2874-83. PubMed ID: 24625057
[TBL] [Abstract][Full Text] [Related]
7. Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain.
Ren C; Morohashi K; Plotnikov AN; Jakoncic J; Smith SG; Li J; Zeng L; Rodriguez Y; Stojanoff V; Walsh M; Zhou MM
Chem Biol; 2015 Feb; 22(2):161-8. PubMed ID: 25660273
[TBL] [Abstract][Full Text] [Related]
8. Live-cell single-molecule tracking reveals co-recognition of H3K27me3 and DNA targets polycomb Cbx7-PRC1 to chromatin.
Zhen CY; Tatavosian R; Huynh TN; Duc HN; Das R; Kokotovic M; Grimm JB; Lavis LD; Lee J; Mejia FJ; Li Y; Yao T; Ren X
Elife; 2016 Oct; 5():. PubMed ID: 27723458
[TBL] [Abstract][Full Text] [Related]
9. The molecular selectivity of UNC3866 inhibitor for Polycomb CBX7 protein from molecular dynamics simulation.
Liu H; Li Z; Li L
Comput Biol Chem; 2018 Jun; 74():339-346. PubMed ID: 29723807
[TBL] [Abstract][Full Text] [Related]
10. A human Polycomb isoform lacking the Pc box does not participate to PRC1 complexes but forms protein assemblies and represses transcription.
Völkel P; Le Faou P; Vandamme J; Pira D; Angrand PO
Epigenetics; 2012 May; 7(5):482-91. PubMed ID: 22419124
[TBL] [Abstract][Full Text] [Related]
11. CBX7 Induces Self-Renewal of Human Normal and Malignant Hematopoietic Stem and Progenitor Cells by Canonical and Non-canonical Interactions.
Jung J; Buisman SC; Weersing E; Dethmers-Ausema A; Zwart E; Schepers H; Dekker MR; Lazare SS; Hammerl F; Skokova Y; Kooistra SM; Klauke K; Poot RA; Bystrykh LV; de Haan G
Cell Rep; 2019 Feb; 26(7):1906-1918.e8. PubMed ID: 30759399
[TBL] [Abstract][Full Text] [Related]
12. The complex CBX7-PRMT1 has a critical role in regulating E-cadherin gene expression and cell migration.
Federico A; Sepe R; Cozzolino F; Piccolo C; Iannone C; Iacobucci I; Pucci P; Monti M; Fusco A
Biochim Biophys Acta Gene Regul Mech; 2019 Apr; 1862(4):509-521. PubMed ID: 30826432
[TBL] [Abstract][Full Text] [Related]
13. RYBP and Cbx7 define specific biological functions of polycomb complexes in mouse embryonic stem cells.
Morey L; Aloia L; Cozzuto L; Benitah SA; Di Croce L
Cell Rep; 2013 Jan; 3(1):60-9. PubMed ID: 23273917
[TBL] [Abstract][Full Text] [Related]
14. Polycomb CBX7 promotes initiation of heritable repression of genes frequently silenced with cancer-specific DNA hypermethylation.
Mohammad HP; Cai Y; McGarvey KM; Easwaran H; Van Neste L; Ohm JE; O'Hagan HM; Baylin SB
Cancer Res; 2009 Aug; 69(15):6322-30. PubMed ID: 19602592
[TBL] [Abstract][Full Text] [Related]
15. Engagement of DNA and H3K27me3 by the CBX8 chromodomain drives chromatin association.
Connelly KE; Weaver TM; Alpsoy A; Gu BX; Musselman CA; Dykhuizen EC
Nucleic Acids Res; 2019 Mar; 47(5):2289-2305. PubMed ID: 30597065
[TBL] [Abstract][Full Text] [Related]
16. Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch.
Peng L; Wang L; Zhang Y; Dong A; Shen WH; Huang Y
J Mol Biol; 2018 Oct; 430(21):4245-4259. PubMed ID: 30176245
[TBL] [Abstract][Full Text] [Related]
17. Polycomb inhibits histone acetylation by CBP by binding directly to its catalytic domain.
Tie F; Banerjee R; Fu C; Stratton CA; Fang M; Harte PJ
Proc Natl Acad Sci U S A; 2016 Feb; 113(6):E744-53. PubMed ID: 26802126
[TBL] [Abstract][Full Text] [Related]
18. Governing the Silencing State of Chromatin: The Roles of Polycomb Repressive Complex 1 in Arabidopsis.
Yang X; Tong A; Yan B; Wang X
Plant Cell Physiol; 2017 Feb; 58(2):198-206. PubMed ID: 28069891
[TBL] [Abstract][Full Text] [Related]
19. Phosphorylation of CBX2 controls its nucleosome-binding specificity.
Kawaguchi T; Machida S; Kurumizaka H; Tagami H; Nakayama JI
J Biochem; 2017 Nov; 162(5):343-355. PubMed ID: 28992316
[TBL] [Abstract][Full Text] [Related]
20. MGA, L3MBTL2 and E2F6 determine genomic binding of the non-canonical Polycomb repressive complex PRC1.6.
Stielow B; Finkernagel F; Stiewe T; Nist A; Suske G
PLoS Genet; 2018 Jan; 14(1):e1007193. PubMed ID: 29381691
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]