BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 31424401)

  • 1. Neuron-Specific Apolipoprotein E4 (1-272) Fragment Induces Tau Hyperphosphorylation and Axonopathy via Triggering Endoplasmic Reticulum Stress.
    Liang T; Xue F; Hang W; Wen B; Zhang Q; Chen J; Liu X; Chen J
    J Alzheimers Dis; 2019; 71(2):597-611. PubMed ID: 31424401
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SIL1 Rescued Bip Elevation-Related Tau Hyperphosphorylation in ER Stress.
    Liu ZC; Chu J; Lin L; Song J; Ning LN; Luo HB; Yang SS; Shi Y; Wang Q; Qu N; Zhang Q; Wang JZ; Tian Q
    Mol Neurobiol; 2016 Mar; 53(2):983-994. PubMed ID: 25575678
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice.
    Brecht WJ; Harris FM; Chang S; Tesseur I; Yu GQ; Xu Q; Dee Fish J; Wyss-Coray T; Buttini M; Mucke L; Mahley RW; Huang Y
    J Neurosci; 2004 Mar; 24(10):2527-34. PubMed ID: 15014128
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Prominent axonopathy and disruption of axonal transport in transgenic mice expressing human apolipoprotein E4 in neurons of brain and spinal cord.
    Tesseur I; Van Dorpe J; Bruynseels K; Bronfman F; Sciot R; Van Lommel A; Van Leuven F
    Am J Pathol; 2000 Nov; 157(5):1495-510. PubMed ID: 11073810
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Increased tau phosphorylation in apolipoprotein E4 transgenic mice is associated with activation of extracellular signal-regulated kinase: modulation by zinc.
    Harris FM; Brecht WJ; Xu Q; Mahley RW; Huang Y
    J Biol Chem; 2004 Oct; 279(43):44795-801. PubMed ID: 15322121
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of truncated-ApoE4 overexpression on tau phosphorylation in cultured N2a cells.
    Zhou J; Chen J; Feng Y
    J Huazhong Univ Sci Technolog Med Sci; 2006; 26(3):272-4. PubMed ID: 16961266
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Astrocyte-secreted glypican-4 drives APOE4-dependent tau hyperphosphorylation.
    Saroja SR; Gorbachev K; Julia T; Goate AM; Pereira AC
    Proc Natl Acad Sci U S A; 2022 Aug; 119(34):e2108870119. PubMed ID: 35969759
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Bip enhanced the association of GSK-3β with tau during ER stress both in vivo and in vitro.
    Liu ZC; Fu ZQ; Song J; Zhang JY; Wei YP; Chu J; Han L; Qu N; Wang JZ; Tian Q
    J Alzheimers Dis; 2012; 29(4):727-40. PubMed ID: 22460328
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector.
    Wang C; Najm R; Xu Q; Jeong DE; Walker D; Balestra ME; Yoon SY; Yuan H; Li G; Miller ZA; Miller BL; Malloy MJ; Huang Y
    Nat Med; 2018 May; 24(5):647-657. PubMed ID: 29632371
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
    Shi Y; Yamada K; Liddelow SA; Smith ST; Zhao L; Luo W; Tsai RM; Spina S; Grinberg LT; Rojas JC; Gallardo G; Wang K; Roh J; Robinson G; Finn MB; Jiang H; Sullivan PM; Baufeld C; Wood MW; Sutphen C; McCue L; Xiong C; Del-Aguila JL; Morris JC; Cruchaga C; ; Fagan AM; Miller BL; Boxer AL; Seeley WW; Butovsky O; Barres BA; Paul SM; Holtzman DM
    Nature; 2017 Sep; 549(7673):523-527. PubMed ID: 28959956
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ApoE4 induces Aβ42, tau, and neuronal pathology in the hippocampus of young targeted replacement apoE4 mice.
    Liraz O; Boehm-Cagan A; Michaelson DM
    Mol Neurodegener; 2013 May; 8():16. PubMed ID: 23684315
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bidirectional interplay of HSF1 degradation and UPR activation promotes tau hyperphosphorylation.
    Kim E; Sakata K; Liao FF
    PLoS Genet; 2017 Jul; 13(7):e1006849. PubMed ID: 28678786
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Abeta, tau and ApoE4 in Alzheimer's disease: the axonal connection.
    Adalbert R; Gilley J; Coleman MP
    Trends Mol Med; 2007 Apr; 13(4):135-42. PubMed ID: 17344096
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice.
    Tesseur I; Van Dorpe J; Spittaels K; Van den Haute C; Moechars D; Van Leuven F
    Am J Pathol; 2000 Mar; 156(3):951-64. PubMed ID: 10702411
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Berberine attenuates axonal transport impairment and axonopathy induced by Calyculin A in N2a cells.
    Liu X; Zhou J; Abid MD; Yan H; Huang H; Wan L; Feng Z; Chen J
    PLoS One; 2014; 9(4):e93974. PubMed ID: 24713870
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Apolipoprotein E4 causes age- and Tau-dependent impairment of GABAergic interneurons, leading to learning and memory deficits in mice.
    Andrews-Zwilling Y; Bien-Ly N; Xu Q; Li G; Bernardo A; Yoon SY; Zwilling D; Yan TX; Chen L; Huang Y
    J Neurosci; 2010 Oct; 30(41):13707-17. PubMed ID: 20943911
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Possible role of tau in mediating pathological effects of apoE4 in vivo prior to and following activation of the amyloid cascade.
    Inbar D; Belinson H; Rosenman H; Michaelson DM
    Neurodegener Dis; 2010; 7(1-3):16-23. PubMed ID: 20160452
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Endoplasmic reticulum stress induces tau pathology and forms a vicious cycle: implication in Alzheimer's disease pathogenesis.
    Ho YS; Yang X; Lau JC; Hung CH; Wuwongse S; Zhang Q; Wang J; Baum L; So KF; Chang RC
    J Alzheimers Dis; 2012; 28(4):839-54. PubMed ID: 22101233
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology.
    Rueli RH; Torres DJ; Dewing AS; Kiyohara AC; Barayuga SM; Bellinger MT; Uyehara-Lock JH; White LR; Moreira PI; Berry MJ; Perry G; Bellinger FP
    J Alzheimers Dis; 2017; 55(2):749-762. PubMed ID: 27802219
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Isoflavones prevent endoplasmic reticulum stress-mediated neuronal degeneration by inhibiting tau hyperphosphorylation in SH-SY5Y cells.
    Park YJ; Jang YM; Kwon YH
    J Med Food; 2009 Jun; 12(3):528-35. PubMed ID: 19627200
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.