BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

330 related articles for article (PubMed ID: 31425749)

  • 1. An oral 2-hydroxypropyl-β-cyclodextrin-loaded spirooxindole-pyrrolizidine derivative restores p53 activity via targeting MDM2 and JNK1/2 in hepatocellular carcinoma.
    Gao X; Wei M; Shan W; Liu Q; Gao J; Liu Y; Zhu S; Yao H
    Pharmacol Res; 2019 Oct; 148():104400. PubMed ID: 31425749
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel all-trans retinoic acid derivative 4-amino‑2‑trifluoromethyl-phenyl retinate inhibits the proliferation of human hepatocellular carcinoma HepG2 cells by inducing G0/G1 cell cycle arrest and apoptosis via upregulation of p53 and ASPP1 and downregulation of iASPP.
    Liu H; Chen F; Zhang L; Zhou Q; Gui S; Wang Y
    Oncol Rep; 2016 Jul; 36(1):333-41. PubMed ID: 27177208
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oral administration of indole substituted dipyrido[2,3-d]pyrimidine derivative exhibits anti-tumor activity via inhibiting AKT and ERK1/2 on hepatocellular carcinoma.
    Gao X; Cen L; Li F; Wen R; Yan H; Yao H; Zhu S
    Biochem Biophys Res Commun; 2018 Nov; 505(3):761-767. PubMed ID: 30293685
    [TBL] [Abstract][Full Text] [Related]  

  • 4. p53-dependent upregulation of miR-16-2 by sanguinarine induces cell cycle arrest and apoptosis in hepatocellular carcinoma.
    Zhang B; Wang X; Deng J; Zheng H; Liu W; Chen S; Tian J; Wang F
    Cancer Lett; 2019 Sep; 459():50-58. PubMed ID: 31163195
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Antiproliferative Activity of Oxypeucedanin via Induction of G
    Park SH; Hong JY; Park HJ; Lee SK
    Molecules; 2020 Jan; 25(3):. PubMed ID: 31979361
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Walsuronoid B induces mitochondrial and lysosomal dysfunction leading to apoptotic rather than autophagic cell death via ROS/p53 signaling pathways in liver cancer.
    Geng YD; Zhang C; Lei JL; Yu P; Xia YZ; Zhang H; Yang L; Kong LY
    Biochem Pharmacol; 2017 Oct; 142():71-86. PubMed ID: 28673807
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibitory effect of oleanolic acid on hepatocellular carcinoma via ERK-p53-mediated cell cycle arrest and mitochondrial-dependent apoptosis.
    Wang X; Bai H; Zhang X; Liu J; Cao P; Liao N; Zhang W; Wang Z; Hai C
    Carcinogenesis; 2013 Jun; 34(6):1323-30. PubMed ID: 23404993
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hemistepsin A Inhibits Cell Proliferation and Induces G0/G1-Phase Arrest, Cellular Senescence and Apoptosis Via the AMPK and p53/p21 Signals in Human Hepatocellular Carcinoma.
    Baek SY; Hwang UW; Suk HY; Kim YW
    Biomolecules; 2020 May; 10(5):. PubMed ID: 32375410
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MDM2 antagonist can inhibit tumor growth in hepatocellular carcinoma with different types of p53 in vitro.
    Wang J; Zheng T; Chen X; Song X; Meng X; Bhatta N; Pan S; Jiang H; Liu L
    J Gastroenterol Hepatol; 2011 Feb; 26(2):371-7. PubMed ID: 21261729
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ψ-Bufarenogin, a novel anti-tumor compound, suppresses liver cancer growth by inhibiting receptor tyrosine kinase-mediated signaling.
    Ding J; Wen W; Xiang D; Yin P; Liu Y; Liu C; He G; Cheng Z; Yin J; Sheng C; Zhang W; Nan F; Ye W; Zhang X; Wang H
    Oncotarget; 2015 May; 6(13):11627-39. PubMed ID: 25890498
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [ShRNA-mediated silencing of MDM2 inhibits growth of HepG2 hepatocellular carcinoma cells xenografted in nude mice].
    Zhao YY; Li YG; Sun YJ; Liu HP; Yang ZC; Zhang DD; Zhao CY
    Zhonghua Gan Zang Bing Za Zhi; 2013 Mar; 21(3):213-7. PubMed ID: 23967744
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Romidepsin induces G2/M phase arrest via Erk/cdc25C/cdc2/cyclinB pathway and apoptosis induction through JNK/c-Jun/caspase3 pathway in hepatocellular carcinoma cells.
    Sun WJ; Huang H; He B; Hu DH; Li PH; Yu YJ; Zhou XH; Lv Z; Zhou L; Hu TY; Yao ZC; Lu MD; Shen X; Zheng ZQ
    Biochem Pharmacol; 2017 Mar; 127():90-100. PubMed ID: 28012958
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling.
    Chen B; Wei W; Ma L; Yang B; Gill RM; Chua MS; Butte AJ; So S
    Gastroenterology; 2017 Jun; 152(8):2022-2036. PubMed ID: 28284560
    [TBL] [Abstract][Full Text] [Related]  

  • 14. NCPMF-60 induces G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.
    Dai QS; Liu W; Wang XB; Lu N; Gong DD; Kong LY; Guo QL
    Anticancer Drugs; 2011 Jan; 22(1):46-57. PubMed ID: 20948430
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibiting MDM2-p53 Interaction Suppresses Tumor Growth in Patient-Derived Non-Small Cell Lung Cancer Xenograft Models.
    Hai J; Sakashita S; Allo G; Ludkovski O; Ng C; Shepherd FA; Tsao MS
    J Thorac Oncol; 2015 Aug; 10(8):1172-80. PubMed ID: 26200271
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MDM2-NFAT1 dual inhibitor, MA242: Effective against hepatocellular carcinoma, independent of p53.
    Wang W; Cheng JW; Qin JJ; Hu B; Li X; Nijampatnam B; Velu SE; Fan J; Yang XR; Zhang R
    Cancer Lett; 2019 Sep; 459():156-167. PubMed ID: 31181320
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p53/mdm2 feedback loop sustains miR-221 expression and dictates the response to anticancer treatments in hepatocellular carcinoma.
    Fornari F; Milazzo M; Galassi M; Callegari E; Veronese A; Miyaaki H; Sabbioni S; Mantovani V; Marasco E; Chieco P; Negrini M; Bolondi L; Gramantieri L
    Mol Cancer Res; 2014 Feb; 12(2):203-16. PubMed ID: 24324033
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antihepatocellular Carcinoma Potential of Tetramethylpyrazine Induces Cell Cycle Modulation and Mitochondrial-Dependent Apoptosis: Regulation of p53 Signaling Pathway in HepG2 Cells In Vitro.
    Bi L; Yan X; Chen W; Gao J; Qian L; Qiu S
    Integr Cancer Ther; 2016 Jun; 15(2):226-36. PubMed ID: 27179035
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of esophageal-carcinoma cell proliferation by genistein via suppression of JAK1/2-STAT3 and AKT/MDM2/p53 signaling pathways.
    Gao J; Xia R; Chen J; Gao J; Luo X; Ke C; Ren C; Li J; Mi Y
    Aging (Albany NY); 2020 Apr; 12(7):6240-6259. PubMed ID: 32276266
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ethyl pyruvate inhibits proliferation and induces apoptosis of hepatocellular carcinoma via regulation of the HMGB1-RAGE and AKT pathways.
    Cheng P; Dai W; Wang F; Lu J; Shen M; Chen K; Li J; Zhang Y; Wang C; Yang J; Zhu R; Zhang H; Zheng Y; Guo CY; Xu L
    Biochem Biophys Res Commun; 2014 Jan; 443(4):1162-8. PubMed ID: 24361892
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.