BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

749 related articles for article (PubMed ID: 31431076)

  • 1. A kinome-wide screen using a NanoLuc LATS luminescent biosensor identifies ALK as a novel regulator of the Hippo pathway in tumorigenesis and immune evasion.
    Nouri K; Azad T; Lightbody E; Khanal P; Nicol CJ; Yang X
    FASEB J; 2019 Nov; 33(11):12487-12499. PubMed ID: 31431076
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis.
    Azad T; Janse van Rensburg HJ; Lightbody ED; Neveu B; Champagne A; Ghaffari A; Kay VR; Hao Y; Shen H; Yeung B; Croy BA; Guan KL; Pouliot F; Zhang J; Nicol CJB; Yang X
    Nat Commun; 2018 Mar; 9(1):1061. PubMed ID: 29535383
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Hippo Pathway Component TAZ Promotes Immune Evasion in Human Cancer through PD-L1.
    Janse van Rensburg HJ; Azad T; Ling M; Hao Y; Snetsinger B; Khanal P; Minassian LM; Graham CH; Rauh MJ; Yang X
    Cancer Res; 2018 Mar; 78(6):1457-1470. PubMed ID: 29339539
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway.
    Toloczko A; Guo F; Yuen HF; Wen Q; Wood SA; Ong YS; Chan PY; Shaik AA; Gunaratne J; Dunne MJ; Hong W; Chan SW
    Cancer Res; 2017 Sep; 77(18):4921-4933. PubMed ID: 28720576
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Deregulation of the Hippo pathway in mouse mammary stem cells promotes mammary tumorigenesis.
    Li H; Gumbiner BM
    Mamm Genome; 2016 Dec; 27(11-12):556-564. PubMed ID: 27601049
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A gain-of-functional screen identifies the Hippo pathway as a central mediator of receptor tyrosine kinases during tumorigenesis.
    Azad T; Nouri K; Janse van Rensburg HJ; Maritan SM; Wu L; Hao Y; Montminy T; Yu J; Khanal P; Mulligan LM; Yang X
    Oncogene; 2020 Jan; 39(2):334-355. PubMed ID: 31477837
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis.
    Moroishi T; Park HW; Qin B; Chen Q; Meng Z; Plouffe SW; Taniguchi K; Yu FX; Karin M; Pan D; Guan KL
    Genes Dev; 2015 Jun; 29(12):1271-84. PubMed ID: 26109050
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of PTPN12 Phosphatase as a Novel Negative Regulator of Hippo Pathway Effectors YAP/TAZ in Breast Cancer.
    Sarmasti Emami S; Ge A; Zhang D; Hao Y; Ling M; Rubino R; Nicol CJB; Wang W; Yang X
    Int J Mol Sci; 2024 Apr; 25(7):. PubMed ID: 38612874
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Heat stress activates YAP/TAZ to induce the heat shock transcriptome.
    Luo M; Meng Z; Moroishi T; Lin KC; Shen G; Mo F; Shao B; Wei X; Zhang P; Wei Y; Guan KL
    Nat Cell Biol; 2020 Dec; 22(12):1447-1459. PubMed ID: 33199845
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Arhgef7 promotes activation of the Hippo pathway core kinase Lats.
    Heidary Arash E; Song KM; Song S; Shiban A; Attisano L
    EMBO J; 2014 Dec; 33(24):2997-3011. PubMed ID: 25425573
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Hippo pathway effector proteins YAP and TAZ have both distinct and overlapping functions in the cell.
    Plouffe SW; Lin KC; Moore JL; Tan FE; Ma S; Ye Z; Qiu Y; Ren B; Guan KL
    J Biol Chem; 2018 Jul; 293(28):11230-11240. PubMed ID: 29802201
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor (LATS) Biosensor.
    Azad T; Nouri K; Janse van Rensburg HJ; Hao Y; Yang X
    J Vis Exp; 2018 Sep; (139):. PubMed ID: 30272653
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of Prolyl isomerase Pin1 as a novel positive regulator of YAP/TAZ in breast cancer cells.
    Khanal P; Yeung B; Zhao Y; Yang X
    Sci Rep; 2019 Apr; 9(1):6394. PubMed ID: 31015482
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ski regulates Hippo and TAZ signaling to suppress breast cancer progression.
    Rashidian J; Le Scolan E; Ji X; Zhu Q; Mulvihill MM; Nomura D; Luo K
    Sci Signal; 2015 Feb; 8(363):ra14. PubMed ID: 25670202
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tumor suppressor LATS1 is a negative regulator of oncogene YAP.
    Hao Y; Chun A; Cheung K; Rashidi B; Yang X
    J Biol Chem; 2008 Feb; 283(9):5496-509. PubMed ID: 18158288
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A feed forward loop enforces YAP/TAZ signaling during tumorigenesis.
    Gill MK; Christova T; Zhang YY; Gregorieff A; Zhang L; Narimatsu M; Song S; Xiong S; Couzens AL; Tong J; Krieger JR; Moran MF; Zlotta AR; van der Kwast TH; Gingras AC; Sicheri F; Wrana JL; Attisano L
    Nat Commun; 2018 Aug; 9(1):3510. PubMed ID: 30158528
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PAR1 participates in the ability of multidrug resistance and tumorigenesis by controlling Hippo-YAP pathway.
    Fujimoto D; Ueda Y; Hirono Y; Goi T; Yamaguchi A
    Oncotarget; 2015 Oct; 6(33):34788-99. PubMed ID: 26431277
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SRC tyrosine kinase activates the YAP/TAZ axis and thereby drives tumor growth and metastasis.
    Lamar JM; Xiao Y; Norton E; Jiang ZG; Gerhard GM; Kooner S; Warren JSA; Hynes RO
    J Biol Chem; 2019 Feb; 294(7):2302-2317. PubMed ID: 30559289
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Non-hippo kinases: indispensable roles in YAP/TAZ signaling and implications in cancer therapy.
    Zhu J; Wu T; Lin Q
    Mol Biol Rep; 2023 May; 50(5):4565-4578. PubMed ID: 36877351
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PI3K Positively Regulates YAP and TAZ in Mammary Tumorigenesis Through Multiple Signaling Pathways.
    Zhao Y; Montminy T; Azad T; Lightbody E; Hao Y; SenGupta S; Asselin E; Nicol C; Yang X
    Mol Cancer Res; 2018 Jun; 16(6):1046-1058. PubMed ID: 29545474
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 38.