537 related articles for article (PubMed ID: 31434040)
1. Synthesis, structure-activity relationship and trypanocidal activity of pyrazole-imidazoline and new pyrazole-tetrahydropyrimidine hybrids as promising chemotherapeutic agents for Chagas disease.
Monteiro ME; Lechuga G; Lara LS; Souto BA; Viganó MG; Bourguignon SC; Calvet CM; Oliveira FOR; Alves CR; Souza-Silva F; Santos MS; Pereira MCS
Eur J Med Chem; 2019 Nov; 182():111610. PubMed ID: 31434040
[TBL] [Abstract][Full Text] [Related]
2. Structural Optimization and Biological Activity of Pyrazole Derivatives: Virtual Computational Analysis, Recovery Assay and 3D Culture Model as Potential Predictive Tools of Effectiveness against
Orlando LMR; Lechuga GC; da Silva Lara L; Ferreira BS; Pereira CN; Silva RC; Dos Santos MS; Pereira MCS
Molecules; 2021 Nov; 26(21):. PubMed ID: 34771151
[TBL] [Abstract][Full Text] [Related]
3. Efficacy of 2-hydroxy-3-phenylsulfanylmethyl-[1,4]-naphthoquinone derivatives against different Trypanosoma cruzi discrete type units: Identification of a promising hit compound.
Lara LS; Moreira CS; Calvet CM; Lechuga GC; Souza RS; Bourguignon SC; Ferreira VF; Rocha D; Pereira MCS
Eur J Med Chem; 2018 Jan; 144():572-581. PubMed ID: 29289882
[TBL] [Abstract][Full Text] [Related]
4. Synthesis of novel quinine analogs and evaluation of their effects on Trypanosoma cruzi.
Ceole LF; Gandhi H; Villamizar LH; Soares MJ; O'Sullivan TP
Future Med Chem; 2018 Feb; 10(4):391-408. PubMed ID: 29380636
[TBL] [Abstract][Full Text] [Related]
5. Optimization of 1,4-Naphthoquinone Hit Compound: A Computational, Phenotypic, and In Vivo Screening against
Lara LS; Lechuga GC; Moreira CDS; Santos TB; Ferreira VF; da Rocha DR; Pereira MCS
Molecules; 2021 Jan; 26(2):. PubMed ID: 33467422
[TBL] [Abstract][Full Text] [Related]
6. Synthesis, physicochemical properties of allopurinol derivatives and their biological activity against Trypanosoma cruzi.
Raviolo MA; Solana ME; Novoa MM; Gualdesi MS; Alba-Soto CD; Briñón MC
Eur J Med Chem; 2013 Nov; 69():455-64. PubMed ID: 24090917
[TBL] [Abstract][Full Text] [Related]
7. Synthesis by Microwave Irradiation, Molecular Structural Analysis and Trypanocidal Activity of Novel Pyrazole-tetrahydropyrimidine Derivatives.
Pereira CN; de Oliveira JA; da Silva Lara L; Rocha Orlando LM; de Souza Pereira MC; Dos Santos MS
Curr Org Synth; 2023; 20(7):707-715. PubMed ID: 36627780
[TBL] [Abstract][Full Text] [Related]
8. Structural design, synthesis and pharmacological evaluation of thiazoles against Trypanosoma cruzi.
de Oliveira Filho GB; Cardoso MVO; Espíndola JWP; Oliveira E Silva DA; Ferreira RS; Coelho PL; Anjos PSD; Santos ES; Meira CS; Moreira DRM; Soares MBP; Leite ACL
Eur J Med Chem; 2017 Dec; 141():346-361. PubMed ID: 29031078
[TBL] [Abstract][Full Text] [Related]
9. Simple dialkyl pyrazole-3,5-dicarboxylates show in vitro and in vivo activity against disease-causing trypanosomatids.
Reviriego F; Olmo F; Navarro P; Marín C; Ramírez-Macías I; García-España E; Albelda MT; Gutiérrez-Sánchez R; Sánchez-Moreno M; Arán VJ
Parasitology; 2017 Aug; 144(9):1133-1143. PubMed ID: 28367781
[TBL] [Abstract][Full Text] [Related]
10. In vivo trypanosomicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against acute and chronic phases of Chagas disease.
Sánchez-Moreno M; Sanz AM; Gómez-Contreras F; Navarro P; Marín C; Ramírez-Macias I; Rosales MJ; Olmo F; Garcia-Aranda I; Campayo L; Cano C; Arrebola F; Yunta MJ
J Med Chem; 2011 Feb; 54(4):970-9. PubMed ID: 21229977
[TBL] [Abstract][Full Text] [Related]
11. In Vitro and in Vivo Anti-Trypanosoma cruzi Activity of New Arylamine Mannich Base-Type Derivatives.
Moreno-Viguri E; Jiménez-Montes C; Martín-Escolano R; Santivañez-Veliz M; Martin-Montes A; Azqueta A; Jimenez-Lopez M; Zamora Ledesma S; Cirauqui N; López de Ceráin A; Marín C; Sánchez-Moreno M; Pérez-Silanes S
J Med Chem; 2016 Dec; 59(24):10929-10945. PubMed ID: 28002965
[TBL] [Abstract][Full Text] [Related]
12. Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which induce apoptotic parasite death.
da Silva EB; Oliveira E Silva DA; Oliveira AR; da Silva Mendes CH; Dos Santos TA; da Silva AC; de Castro MC; Ferreira RS; Moreira DR; Cardoso MV; de Simone CA; Pereira VR; Leite AC
Eur J Med Chem; 2017 Apr; 130():39-50. PubMed ID: 28242550
[TBL] [Abstract][Full Text] [Related]
13. Trypanocidal activity of new 1,6-diphenyl-1H-pyrazolo[3,4-b]pyridine derivatives: Synthesis, in vitro and in vivo studies.
Ribeiro JLS; Soares JCAV; Portapilla GB; Providello MV; Lima CHS; Muri EMF; de Albuquerque S; Dias LRS
Bioorg Med Chem; 2021 Jan; 29():115855. PubMed ID: 33199200
[TBL] [Abstract][Full Text] [Related]
14. New oxirane derivatives of 1,4-naphthoquinones and their evaluation against T. cruzi epimastigote forms.
Carneiro PF; do Nascimento SB; Pinto AV; Pinto Mdo C; Lechuga GC; Santos DO; dos Santos Júnior HM; Resende JA; Bourguignon SC; Ferreira VF
Bioorg Med Chem; 2012 Aug; 20(16):4995-5000. PubMed ID: 22795899
[TBL] [Abstract][Full Text] [Related]
15. Phenotypic evaluation and in silico ADMET properties of novel arylimidamides in acute mouse models of
da Silva CF; Batista DDGJ; de Araújo JS; Cunha-Junior EF; Stephens CE; Banerjee M; Farahat AA; Akay S; Fisher MK; Boykin DW; Soeiro MNC
Drug Des Devel Ther; 2017; 11():1095-1105. PubMed ID: 28435221
[TBL] [Abstract][Full Text] [Related]
16. In vitro and in vivo studies of the trypanocidal activity of a diarylthiophene diamidine against Trypanosoma cruzi.
da Silva CF; Batista MM; Batista Dda G; de Souza EM; da Silva PB; de Oliveira GM; Meuser AS; Shareef AR; Boykin DW; Soeiro Mde N
Antimicrob Agents Chemother; 2008 Sep; 52(9):3307-14. PubMed ID: 18625779
[TBL] [Abstract][Full Text] [Related]
17. Trypanocidal activity of 5,6-dihydropyran-2-ones against free trypomastigotes forms of Trypanosoma cruzi.
de Fátima A; Marquissolo C; de Albuquerque S; Carraro-Abrahão AA; Pilli RA
Eur J Med Chem; 2006 Oct; 41(10):1210-3. PubMed ID: 16815596
[TBL] [Abstract][Full Text] [Related]
18. In vitro and in vivo trypanosomicidal activity of pyrazole-containing macrocyclic and macrobicyclic polyamines: their action on acute and chronic phases of Chagas disease.
Sánchez-Moreno M; Marín C; Navarro P; Lamarque L; García-España E; Miranda C; Huertas O; Olmo F; Gómez-Contreras F; Pitarch J; Arrebola F
J Med Chem; 2012 May; 55(9):4231-43. PubMed ID: 22443115
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and biological evaluation of quinones derived from natural product komaroviquinone as anti-Trypanosoma cruzi agents.
Suto Y; Nakajima-Shimada J; Yamagiwa N; Onizuka Y; Iwasaki G
Bioorg Med Chem Lett; 2015 Aug; 25(15):2967-71. PubMed ID: 26037321
[TBL] [Abstract][Full Text] [Related]
20. Hit-to-lead optimization of novel 2-alkylaminomethylquinoline derivatives as anti-chagas agents.
Muscia GC; Roldán Pacheco FJ; Asís SE; Buldain GY; Frank FM
Eur J Med Chem; 2020 Jan; 186():111877. PubMed ID: 31771829
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
