BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 31434318)

  • 1. RAC1B Suppresses TGF-β-Dependent Chemokinesis and Growth Inhibition through an Autoregulatory Feed-Forward Loop Involving PAR2 and ALK5.
    Otterbein H; Mihara K; Hollenberg MD; Lehnert H; Witte D; Ungefroren H
    Cancers (Basel); 2019 Aug; 11(8):. PubMed ID: 31434318
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RAC1B Suppresses TGF-β1-Dependent Cell Migration in Pancreatic Carcinoma Cells through Inhibition of the TGF-β Type I Receptor ALK5.
    Ungefroren H; Otterbein H; Fiedler C; Mihara K; Hollenberg MD; Gieseler F; Lehnert H; Witte D
    Cancers (Basel); 2019 May; 11(5):. PubMed ID: 31108998
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RAC1B Induces SMAD7 via USP26 to Suppress TGFβ1-Dependent Cell Migration in Mesenchymal-Subtype Carcinoma Cells.
    Ungefroren H; Kumarasinghe A; Musfeldt M; Fiedler C; Lehnert H; Marquardt JU
    Cancers (Basel); 2020 Jun; 12(6):. PubMed ID: 32545415
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Role of PAR2 in TGF-β1-Induced ERK Activation and Cell Motility.
    Ungefroren H; Witte D; Fiedler C; Gädeken T; Kaufmann R; Lehnert H; Gieseler F; Rauch BH
    Int J Mol Sci; 2017 Dec; 18(12):. PubMed ID: 29261154
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RAC1B: A Guardian of the Epithelial Phenotype and Protector Against Epithelial-Mesenchymal Transition.
    Zinn R; Otterbein H; Lehnert H; Ungefroren H
    Cells; 2019 Dec; 8(12):. PubMed ID: 31817229
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proteinase-activated receptor 2 promotes TGF-β-dependent cell motility in pancreatic cancer cells by sustaining expression of the TGF-β type I receptor ALK5.
    Zeeh F; Witte D; Gädeken T; Rauch BH; Grage-Griebenow E; Leinung N; Fromm SJ; Stölting S; Mihara K; Kaufmann R; Settmacher U; Lehnert H; Hollenberg MD; Ungefroren H
    Oncotarget; 2016 Jul; 7(27):41095-41109. PubMed ID: 27248167
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Negative regulation of TGF-β1-induced MKK6-p38 and MEK-ERK signalling and epithelial-mesenchymal transition by Rac1b.
    Witte D; Otterbein H; Förster M; Giehl K; Zeiser R; Lehnert H; Ungefroren H
    Sci Rep; 2017 Dec; 7(1):17313. PubMed ID: 29229918
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Negative Control of Cell Migration by Rac1b in Highly Metastatic Pancreatic Cancer Cells Is Mediated by Sequential Induction of Nonactivated Smad3 and Biglycan.
    Otterbein H; Lehnert H; Ungefroren H
    Cancers (Basel); 2019 Dec; 11(12):. PubMed ID: 31817656
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transforming Growth Factor-
    Ungefroren H; Witte D; Mihara K; Rauch BH; Henklein P; Jöhren O; Bonni S; Settmacher U; Lehnert H; Hollenberg MD; Kaufmann R; Gieseler F
    Mol Pharmacol; 2017 Nov; 92(5):519-532. PubMed ID: 28842394
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rac1b negatively regulates TGF-β1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling.
    Ungefroren H; Sebens S; Giehl K; Helm O; Groth S; Fändrich F; Röcken C; Sipos B; Lehnert H; Gieseler F
    Oncotarget; 2014 Jan; 5(1):277-90. PubMed ID: 24378395
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RAC1b Collaborates with TAp73α-SMAD4 Signaling to Induce Biglycan Expression and Inhibit Basal and TGF-β-Driven Cell Motility in Human Pancreatic Cancer.
    Ungefroren H; Reimann J; Konukiewitz B; Braun R; Wellner UF; Lehnert H; Marquardt JU
    Biomedicines; 2024 Jan; 12(1):. PubMed ID: 38255305
    [TBL] [Abstract][Full Text] [Related]  

  • 12. RAC1B Regulation of
    Ungefroren H; Otterbein H; Wellner UF; Keck T; Lehnert H; Marquardt JU
    Cancers (Basel); 2020 Nov; 12(12):. PubMed ID: 33260366
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Suppressive Role of ACVR1/ALK2 in Basal and TGFβ1-Induced Cell Migration in Pancreatic Ductal Adenocarcinoma Cells and Identification of a Self-Perpetuating Autoregulatory Loop Involving the Small GTPase RAC1b.
    Ungefroren H; Braun R; Lapshyna O; Konukiewitz B; Wellner UF; Lehnert H; Marquardt JU
    Biomedicines; 2022 Oct; 10(10):. PubMed ID: 36289908
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TGF-β1 induces proteinase-activated receptor 2 (PAR2) expression in endometriotic stromal cells and stimulates PAR2 activation-induced secretion of IL-6.
    Saito A; Osuga Y; Yoshino O; Takamura M; Hirata T; Hirota Y; Koga K; Harada M; Takemura Y; Yano T; Taketani Y
    Hum Reprod; 2011 Jul; 26(7):1892-8. PubMed ID: 21546388
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dissecting the role of TGF-beta type I receptor/ALK5 in pancreatic ductal adenocarcinoma: Smad activation is crucial for both the tumor suppressive and prometastatic function.
    Schniewind B; Groth S; Sebens Müerköster S; Sipos B; Schäfer H; Kalthoff H; Fändrich F; Ungefroren H
    Oncogene; 2007 Jul; 26(33):4850-62. PubMed ID: 17297450
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TGF-β1-induced cell migration in pancreatic carcinoma cells is RAC1 and NOX4-dependent and requires RAC1 and NOX4-dependent activation of p38 MAPK.
    Witte D; Bartscht T; Kaufmann R; Pries R; Settmacher U; Lehnert H; Ungefroren H
    Oncol Rep; 2017 Dec; 38(6):3693-3701. PubMed ID: 29039574
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TGF-β-Dependent Growth Arrest and Cell Migration in Benign and Malignant Breast Epithelial Cells Are Antagonistically Controlled by Rac1 and Rac1b.
    Melzer C; von der Ohe J; Hass R; Ungefroren H
    Int J Mol Sci; 2017 Jul; 18(7):. PubMed ID: 28726720
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Proteinase-Activated Receptor 2 Is a Novel Regulator of TGF-β Signaling in Pancreatic Cancer.
    Witte D; Zeeh F; Gädeken T; Gieseler F; Rauch BH; Settmacher U; Kaufmann R; Lehnert H; Ungefroren H
    J Clin Med; 2016 Nov; 5(12):. PubMed ID: 27916875
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Overexpression of ALK5 Induces Human Tenon's Capsule Fibroblasts Transdifferentiation and Fibrosis In Vitro.
    Fu SH; Wang HY; Zhang JY; Shi HM; Zhang N; Ye W; Xiao YQ
    Curr Eye Res; 2017 Jul; 42(7):1018-1028. PubMed ID: 28632033
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DA-Raf-Mediated Suppression of the Ras--ERK Pathway Is Essential for TGF-β1-Induced Epithelial-Mesenchymal Transition in Alveolar Epithelial Type 2 Cells.
    Watanabe-Takano H; Takano K; Hatano M; Tokuhisa T; Endo T
    PLoS One; 2015; 10(5):e0127888. PubMed ID: 25996975
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.