These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 31434318)

  • 21. TGF-β Signal Transduction in Pancreatic Carcinoma Cells is Sensitive to Inhibition by the Src Tyrosine Kinase Inhibitor AZM475271.
    Bartscht T; Rosien B; Rades D; Kaufmann R; Biersack H; Lehnert H; Ungefroren H
    Anticancer Agents Med Chem; 2017; 17(7):966-972. PubMed ID: 27671303
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Autocrine TGFβ1 Opposes Exogenous TGFβ1-Induced Cell Migration and Growth Arrest through Sustainment of a Feed-Forward Loop Involving MEK-ERK Signaling.
    Ungefroren H; Christl J; Eiden C; Wellner UF; Lehnert H; Marquardt JU
    Cancers (Basel); 2021 Mar; 13(6):. PubMed ID: 33802809
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Signaling Crosstalk of TGF-β/ALK5 and PAR2/PAR1: A Complex Regulatory Network Controlling Fibrosis and Cancer.
    Ungefroren H; Gieseler F; Kaufmann R; Settmacher U; Lehnert H; Rauch BH
    Int J Mol Sci; 2018 May; 19(6):. PubMed ID: 29795022
    [TBL] [Abstract][Full Text] [Related]  

  • 24. TGF-β1/ALK5-induced monocyte migration involves PI3K and p38 pathways and is not negatively affected by diabetes mellitus.
    Olieslagers S; Pardali E; Tchaikovski V; ten Dijke P; Waltenberger J
    Cardiovasc Res; 2011 Aug; 91(3):510-8. PubMed ID: 21478266
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542.
    Laping NJ; Grygielko E; Mathur A; Butter S; Bomberger J; Tweed C; Martin W; Fornwald J; Lehr R; Harling J; Gaster L; Callahan JF; Olson BA
    Mol Pharmacol; 2002 Jul; 62(1):58-64. PubMed ID: 12065755
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Dasatinib blocks transcriptional and promigratory responses to transforming growth factor-beta in pancreatic adenocarcinoma cells through inhibition of Smad signalling: implications for in vivo mode of action.
    Bartscht T; Rosien B; Rades D; Kaufmann R; Biersack H; Lehnert H; Gieseler F; Ungefroren H
    Mol Cancer; 2015 Nov; 14():199. PubMed ID: 26588899
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGF-beta-mediated activation of the ALK5-Smad 3 pathway.
    Yoo YA; Kang MH; Kim JS; Oh SC
    Carcinogenesis; 2008 Mar; 29(3):480-90. PubMed ID: 18174246
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Proteinase-activated receptor 2 (PAR2) in hepatic stellate cells - evidence for a role in hepatocellular carcinoma growth in vivo.
    Mußbach F; Ungefroren H; Günther B; Katenkamp K; Henklein P; Westermann M; Settmacher U; Lenk L; Sebens S; Müller JP; Böhmer FD; Kaufmann R
    Mol Cancer; 2016 Jul; 15(1):54. PubMed ID: 27473374
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The Src family kinase inhibitors PP2 and PP1 effectively block TGF-beta1-induced cell migration and invasion in both established and primary carcinoma cells.
    Bartscht T; Lehnert H; Gieseler F; Ungefroren H
    Cancer Chemother Pharmacol; 2012 Aug; 70(2):221-30. PubMed ID: 22699812
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Negative control of TRAIL-R1 signaling by transforming growth factor β1 in pancreatic tumor cells involves Smad-dependent down regulation of TRAIL-R1.
    Radke DI; Ungefroren H; Helm O; Voigt S; Alp G; Braun H; Hübner S; Dilchert J; Sebens S; Adam D; Kalthoff H; Trauzold A
    Cell Signal; 2016 Nov; 28(11):1652-62. PubMed ID: 27492861
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Proteinase-Activated Receptor 2 May Drive Cancer Progression by Facilitating TGF-β Signaling.
    Ungefroren H; Witte D; Rauch BH; Settmacher U; Lehnert H; Gieseler F; Kaufmann R
    Int J Mol Sci; 2017 Nov; 18(11):. PubMed ID: 29165389
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Role of ALK5/Smad2/3 and MEK1/ERK Signaling in Transforming Growth Factor Beta 1-modulated Growth, Collagen Turnover, and Differentiation of Stem Cells from Apical Papilla of Human Tooth.
    Chang HH; Chang MC; Wu IH; Huang GF; Huang WL; Wang YL; Lee SY; Yeh CY; Guo MK; Chan CP; Hsien HC; Jeng JH
    J Endod; 2015 Aug; 41(8):1272-80. PubMed ID: 26001858
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Gene expression profiling demonstrates that TGF-beta1 signals exclusively through receptor complexes involving Alk5 and identifies targets of TGF-beta signaling.
    Karlsson G; Liu Y; Larsson J; Goumans MJ; Lee JS; Thorgeirsson SS; Ringnér M; Karlsson S
    Physiol Genomics; 2005 May; 21(3):396-403. PubMed ID: 15769904
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Transforming growth factor-β1 up-regulates connexin43 expression in human granulosa cells.
    Chen YC; Chang HM; Cheng JC; Tsai HD; Wu CH; Leung PC
    Hum Reprod; 2015 Sep; 30(9):2190-201. PubMed ID: 26202915
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The Src family kinase inhibitors PP2 and PP1 block TGF-beta1-mediated cellular responses by direct and differential inhibition of type I and type II TGF-beta receptors.
    Ungefroren H; Sebens S; Groth S; Gieseler F; Fändrich F
    Curr Cancer Drug Targets; 2011 May; 11(4):524-35. PubMed ID: 21395548
    [TBL] [Abstract][Full Text] [Related]  

  • 36. ALK5 promotes tumor angiogenesis by upregulating matrix metalloproteinase-9 in tumor cells.
    Safina A; Vandette E; Bakin AV
    Oncogene; 2007 Apr; 26(17):2407-22. PubMed ID: 17072348
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Attenuated ALK5 receptor expression in human pancreatic cancer: correlation with resistance to growth inhibition.
    Baldwin RL; Friess H; Yokoyama M; Lopez ME; Kobrin MS; Büchler MW; Korc M
    Int J Cancer; 1996 Jul; 67(2):283-8. PubMed ID: 8760600
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Differential roles of Src in transforming growth factor-ß regulation of growth arrest, epithelial-to-mesenchymal transition and cell migration in pancreatic ductal adenocarcinoma cells.
    Ungefroren H; Sebens S; Groth S; Gieseler F; Fändrich F
    Int J Oncol; 2011 Mar; 38(3):797-805. PubMed ID: 21225226
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Metformin inhibits TGF-beta 1-induced MCP-1 expression through BAMBI-mediated suppression of MEK/ERK1/2 signalling.
    Liang D; Song Z; Liang W; Li Y; Liu S
    Nephrology (Carlton); 2019 Apr; 24(4):481-488. PubMed ID: 29934960
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Effects of TGF-β1 on plasminogen activation in human dental pulp cells: Role of ALK5/Smad2, TAK1 and MEK/ERK signalling.
    Chang MC; Chang HH; Lin PS; Huang YA; Chan CP; Tsai YL; Lee SY; Jeng PY; Kuo HY; Yeung SY; Jeng JH
    J Tissue Eng Regen Med; 2018 Apr; 12(4):854-863. PubMed ID: 27723266
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.