BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

234 related articles for article (PubMed ID: 31439947)

  • 1. Crystal structure and substrate-induced activation of ADAMTS13.
    Petri A; Kim HJ; Xu Y; de Groot R; Li C; Vandenbulcke A; Vanhoorelbeke K; Emsley J; Crawley JTB
    Nat Commun; 2019 Aug; 10(1):3781. PubMed ID: 31439947
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phylogenetic and functional analysis of ADAMTS13 identifies highly conserved domains essential for allosteric regulation.
    Muia J; Zhu J; Greco SC; Vanhoorelbeke K; Gupta G; Westfield LA; Sadler JE
    Blood; 2019 Apr; 133(17):1899-1908. PubMed ID: 30700419
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanism of von Willebrand factor scissile bond cleavage by a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13).
    Xiang Y; de Groot R; Crawley JT; Lane DA
    Proc Natl Acad Sci U S A; 2011 Jul; 108(28):11602-7. PubMed ID: 21705658
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Exosite interactions contribute to tension-induced cleavage of von Willebrand factor by the antithrombotic ADAMTS13 metalloprotease.
    Gao W; Anderson PJ; Majerus EM; Tuley EA; Sadler JE
    Proc Natl Acad Sci U S A; 2006 Dec; 103(50):19099-104. PubMed ID: 17146059
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Exploring the "minimal" structure of a functional ADAMTS13 by mutagenesis and small-angle X-ray scattering.
    Zhu J; Muia J; Gupta G; Westfield LA; Vanhoorelbeke K; Tolia NH; Sadler JE
    Blood; 2019 Apr; 133(17):1909-1918. PubMed ID: 30692120
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antibodies that conformationally activate ADAMTS13 allosterically enhance metalloprotease domain function.
    Schelpe AS; Petri A; Roose E; Pareyn I; Deckmyn H; De Meyer SF; Crawley JTB; Vanhoorelbeke K
    Blood Adv; 2020 Mar; 4(6):1072-1080. PubMed ID: 32196558
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Simultaneous exposure of sites in von Willebrand factor for glycoprotein Ib binding and ADAMTS13 cleavage: studies with ristocetin.
    Chen J; Ling M; Fu X; López JA; Chung DW
    Arterioscler Thromb Vasc Biol; 2012 Nov; 32(11):2625-30. PubMed ID: 22922961
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor.
    Akiyama M; Takeda S; Kokame K; Takagi J; Miyata T
    Proc Natl Acad Sci U S A; 2009 Nov; 106(46):19274-9. PubMed ID: 19880749
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A model for the conformational activation of the structurally quiescent metalloprotease ADAMTS13 by von Willebrand factor.
    South K; Freitas MO; Lane DA
    J Biol Chem; 2017 Apr; 292(14):5760-5769. PubMed ID: 28209710
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor.
    Crawley JT; de Groot R; Xiang Y; Luken BM; Lane DA
    Blood; 2011 Sep; 118(12):3212-21. PubMed ID: 21715306
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Extensive contacts between ADAMTS13 exosites and von Willebrand factor domain A2 contribute to substrate specificity.
    Gao W; Anderson PJ; Sadler JE
    Blood; 2008 Sep; 112(5):1713-9. PubMed ID: 18492952
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Binding of platelet glycoprotein Ibalpha to von Willebrand factor domain A1 stimulates the cleavage of the adjacent domain A2 by ADAMTS13.
    Nishio K; Anderson PJ; Zheng XL; Sadler JE
    Proc Natl Acad Sci U S A; 2004 Jul; 101(29):10578-83. PubMed ID: 15249683
    [TBL] [Abstract][Full Text] [Related]  

  • 13. N-linked glycan stabilization of the VWF A2 domain.
    Lynch CJ; Lane DA
    Blood; 2016 Mar; 127(13):1711-8. PubMed ID: 26773038
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Allosteric activation of ADAMTS13 by von Willebrand factor.
    Muia J; Zhu J; Gupta G; Haberichter SL; Friedman KD; Feys HB; Deforche L; Vanhoorelbeke K; Westfield LA; Roth R; Tolia NH; Heuser JE; Sadler JE
    Proc Natl Acad Sci U S A; 2014 Dec; 111(52):18584-9. PubMed ID: 25512528
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of the ADAMTS13 cysteine-rich domain in VWF binding and proteolysis.
    de Groot R; Lane DA; Crawley JT
    Blood; 2015 Mar; 125(12):1968-75. PubMed ID: 25564400
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rearranging exosites in noncatalytic domains can redirect the substrate specificity of ADAMTS proteases.
    Gao W; Zhu J; Westfield LA; Tuley EA; Anderson PJ; Sadler JE
    J Biol Chem; 2012 Aug; 287(32):26944-52. PubMed ID: 22707719
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel binding site for ADAMTS13 constitutively exposed on the surface of globular VWF.
    Zanardelli S; Chion AC; Groot E; Lenting PJ; McKinnon TA; Laffan MA; Tseng M; Lane DA
    Blood; 2009 Sep; 114(13):2819-28. PubMed ID: 19587373
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Essential role of the disintegrin-like domain in ADAMTS13 function.
    de Groot R; Bardhan A; Ramroop N; Lane DA; Crawley JT
    Blood; 2009 May; 113(22):5609-16. PubMed ID: 19234142
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A conformation-sensitive monoclonal antibody against the A2 domain of von Willebrand factor reduces its proteolysis by ADAMTS13.
    Zhang J; Ma Z; Dong N; Liu F; Su J; Zhao Y; Shen F; Wang A; Ruan C
    PLoS One; 2011; 6(7):e22157. PubMed ID: 21779388
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of cysteine thiol-based linkages in ADAMTS13 in support of a non-proteolytic regulation of von Willebrand factor.
    Rottensteiner H; Seyfried BK; Kaufmann S; Fiedler C; Dong JF; Zheng XL; Plaimauer B; Scheiflinger F
    J Thromb Haemost; 2019 Dec; 17(12):2099-2109. PubMed ID: 31393047
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.