BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 31445192)

  • 1. Novel conjugates with dual suppression of glutathione S-transferases and tryptophan-2,3-dioxygenase activities for improving hepatocellular carcinoma therapy.
    Hua S; Wang X; Chen F; Gou S
    Bioorg Chem; 2019 Nov; 92():103191. PubMed ID: 31445192
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pt(IV) hybrids containing a TDO inhibitor serve as potential anticancer immunomodulators.
    Hua S; Chen F; Wang X; Wang Y; Gou S
    J Inorg Biochem; 2019 Jun; 195():130-140. PubMed ID: 30952082
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The introduction of immunosuppressor (TDO inhibitor) significantly improved the efficacy of irinotecan in treating hepatocellular carcinoma.
    Liu Q; Hua S; Wang X; Chen F; Gou S
    Cancer Immunol Immunother; 2021 Feb; 70(2):497-508. PubMed ID: 32840656
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Microtubule inhibitors containing immunostimulatory agents promote cancer immunochemotherapy by inhibiting tubulin polymerization and tryptophan-2,3-dioxygenase.
    Hua S; Chen F; Gou S
    Eur J Med Chem; 2020 Feb; 187():111949. PubMed ID: 31830637
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Multifunctional platinum(IV) complexes as immunostimulatory agents to promote cancer immunochemotherapy by inhibiting tryptophan-2,3-dioxygenase.
    Hua S; Chen F; Xu G; Gou S
    Eur J Med Chem; 2019 May; 169():29-41. PubMed ID: 30852385
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of Tryptophan-Dioxygenase Activity Increases the Antitumor Efficacy of Immune Checkpoint Inhibitors.
    Schramme F; Crosignani S; Frederix K; Hoffmann D; Pilotte L; Stroobant V; Preillon J; Driessens G; Van den Eynde BJ
    Cancer Immunol Res; 2020 Jan; 8(1):32-45. PubMed ID: 31806638
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and biological evaluation of indole-2-carboxylic acid derivatives as IDO1/TDO dual inhibitors.
    Cui G; Lai F; Wang X; Chen X; Xu B
    Eur J Med Chem; 2020 Feb; 188():111985. PubMed ID: 31881488
    [TBL] [Abstract][Full Text] [Related]  

  • 8. IDO1/TDO dual inhibitor RY103 targets Kyn-AhR pathway and exhibits preclinical efficacy on pancreatic cancer.
    Liang H; Li T; Fang X; Xing Z; Zhang S; Shi L; Li W; Guo L; Kuang C; Liu H; Yang Q
    Cancer Lett; 2021 Dec; 522():32-43. PubMed ID: 34520819
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Exploring a repurposed candidate with dual hIDO1/hTDO2 inhibitory potential for anticancer efficacy identified through pharmacophore-based virtual screening and in vitro evaluation.
    Aboomar NM; Essam O; Hassan A; Bassiouny AR; Arafa RK
    Sci Rep; 2024 Apr; 14(1):9386. PubMed ID: 38653790
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A cisplatin-based platinum(IV) prodrug containing a glutathione s-transferase inhibitor to reverse cisplatin-resistance in non-small cell lung cancer.
    Chen H; Wang X; Gou S
    J Inorg Biochem; 2019 Apr; 193():133-142. PubMed ID: 30731264
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and molecular modeling of new benzimidazoles as glutathione S-transferase inhibitors and anticancer agents.
    Abd El-Karim SS; Anwar MM; Zaki ER; Elseginy SA; Nofal ZM
    Future Med Chem; 2018 Jan; 10(2):157-181. PubMed ID: 29235906
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evading immunity: new enzyme implicated in cancer.
    Garber K
    J Natl Cancer Inst; 2012 Mar; 104(5):349-52. PubMed ID: 22349199
    [No Abstract]   [Full Text] [Related]  

  • 13. An Aryl Hydrocarbon Receptor-Mediated Amplification Loop That Enforces Cell Migration in ER-/PR-/Her2- Human Breast Cancer Cells.
    Novikov O; Wang Z; Stanford EA; Parks AJ; Ramirez-Cardenas A; Landesman E; Laklouk I; Sarita-Reyes C; Gusenleitner D; Li A; Monti S; Manteiga S; Lee K; Sherr DH
    Mol Pharmacol; 2016 Nov; 90(5):674-688. PubMed ID: 27573671
    [TBL] [Abstract][Full Text] [Related]  

  • 14.
    Yang D; Zhang S; Fang X; Guo L; Hu N; Guo Z; Li X; Yang S; He JC; Kuang C; Yang Q
    J Med Chem; 2019 Oct; 62(20):9161-9174. PubMed ID: 31580660
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol Derivatives as Glutathione Transferase Inhibitors with Favorable Selectivity and Tolerated Toxicity.
    Liu Q; Liu Z; Hua W; Gou S
    J Med Chem; 2021 Feb; 64(3):1701-1712. PubMed ID: 33529017
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.
    Dolusić E; Larrieu P; Moineaux L; Stroobant V; Pilotte L; Colau D; Pochet L; Van den Eynde B; Masereel B; Wouters J; Frédérick R
    J Med Chem; 2011 Aug; 54(15):5320-34. PubMed ID: 21726069
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An inhibitor of glutathione S-transferase omega 1 that selectively targets apoptotic cells.
    Pace NJ; Pimental DR; Weerapana E
    Angew Chem Int Ed Engl; 2012 Aug; 51(33):8365-8. PubMed ID: 22777685
    [No Abstract]   [Full Text] [Related]  

  • 18. Antitumour agents as inhibitors of tryptophan 2,3-dioxygenase.
    Pantouris G; Mowat CG
    Biochem Biophys Res Commun; 2014 Jan; 443(1):28-31. PubMed ID: 24269239
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A strong glutathione S-transferase inhibitor overcomes the P-glycoprotein-mediated resistance in tumor cells. 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) triggers a caspase-dependent apoptosis in MDR1-expressing leukemia cells.
    Turella P; Filomeni G; Dupuis ML; Ciriolo MR; Molinari A; De Maria F; Tombesi M; Cianfriglia M; Federici G; Ricci G; Caccuri AM
    J Biol Chem; 2006 Aug; 281(33):23725-32. PubMed ID: 16769721
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting the IDO1/TDO2-KYN-AhR Pathway for Cancer Immunotherapy - Challenges and Opportunities.
    Cheong JE; Sun L
    Trends Pharmacol Sci; 2018 Mar; 39(3):307-325. PubMed ID: 29254698
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.