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9. Maintenance of AP-2-Dependent Functional Activities of Nef Restricts Pathways of Immune Escape from CD8 T Lymphocyte Responses. Schouest B; Weiler AM; Janaka SK; Myers TA; Das A; Wilder SC; Furlott J; Baddoo M; Flemington EK; Rakasz EG; Evans DT; Friedrich TC; Maness NJ J Virol; 2018 Mar; 92(5):. PubMed ID: 29237831 [TBL] [Abstract][Full Text] [Related]
10. A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor. Bresnahan PA; Yonemoto W; Ferrell S; Williams-Herman D; Geleziunas R; Greene WC Curr Biol; 1998 Nov; 8(22):1235-8. PubMed ID: 9811606 [TBL] [Abstract][Full Text] [Related]
11. Tetherin/BST-2 antagonism by Nef depends on a direct physical interaction between Nef and tetherin, and on clathrin-mediated endocytosis. Serra-Moreno R; Zimmermann K; Stern LJ; Evans DT PLoS Pathog; 2013; 9(7):e1003487. PubMed ID: 23853598 [TBL] [Abstract][Full Text] [Related]
12. HIV-1 Nef Antagonizes SERINC5 Restriction by Downregulation of SERINC5 via the Endosome/Lysosome System. Shi J; Xiong R; Zhou T; Su P; Zhang X; Qiu X; Li H; Li S; Yu C; Wang B; Ding C; Smithgall TE; Zheng YH J Virol; 2018 Jun; 92(11):. PubMed ID: 29514909 [TBL] [Abstract][Full Text] [Related]
13. Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis. Lock M; Greenberg ME; Iafrate AJ; Swigut T; Muench J; Kirchhoff F; Shohdy N; Skowronski J EMBO J; 1999 May; 18(10):2722-33. PubMed ID: 10329619 [TBL] [Abstract][Full Text] [Related]
14. HIV and SIV Nef modulate signal transduction and protein sorting in T cells. Skowronski J; Greenberg ME; Lock M; Mariani R; Salghetti S; Swigut T; Iafrate AJ Cold Spring Harb Symp Quant Biol; 1999; 64():453-63. PubMed ID: 11232322 [No Abstract] [Full Text] [Related]
15. Importance of the N-distal AP-2 binding element in Nef for simian immunodeficiency virus replication and pathogenicity in rhesus macaques. Brenner M; Münch J; Schindler M; Wildum S; Stolte N; Stahl-Hennig C; Fuchs D; Mätz-Rensing K; Franz M; Heeney J; Ten Haaft P; Swigut T; Hrecka K; Skowronski J; Kirchhoff F J Virol; 2006 May; 80(9):4469-81. PubMed ID: 16611907 [TBL] [Abstract][Full Text] [Related]
16. SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue. Kmiec D; Akbil B; Ananth S; Hotter D; Sparrer KMJ; Stürzel CM; Trautz B; Ayouba A; Peeters M; Yao Z; Stagljar I; Passos V; Zillinger T; Goffinet C; Sauter D; Fackler OT; Kirchhoff F PLoS Pathog; 2018 Aug; 14(8):e1007269. PubMed ID: 30125328 [TBL] [Abstract][Full Text] [Related]
17. The downregulation of CD4 and MHC-I by primate lentiviruses: a paradigm for the modulation of cell surface receptors. Piguet V; Schwartz O; Le Gall S; Trono D Immunol Rev; 1999 Apr; 168():51-63. PubMed ID: 10399064 [TBL] [Abstract][Full Text] [Related]
18. The presence of a vpu gene and the lack of Nef-mediated downmodulation of T cell receptor-CD3 are not always linked in primate lentiviruses. Schmökel J; Sauter D; Schindler M; Leendertz FH; Bailes E; Dazza MC; Saragosti S; Bibollet-Ruche F; Peeters M; Hahn BH; Kirchhoff F J Virol; 2011 Jan; 85(2):742-52. PubMed ID: 21068258 [TBL] [Abstract][Full Text] [Related]
19. Tetherin downmodulation by SIVmac Nef lost with the H196Q escape variant is restored by an upstream variant. Schouest B; Leslie GJ; Hoxie JA; Maness NJ PLoS One; 2020; 15(8):e0225420. PubMed ID: 32764749 [TBL] [Abstract][Full Text] [Related]
20. Loss of Nef-mediated CD3 down-regulation in the HIV-1 lineage increases viral infectivity and spread. Mesner D; Hotter D; Kirchhoff F; Jolly C Proc Natl Acad Sci U S A; 2020 Mar; 117(13):7382-7391. PubMed ID: 32179688 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]