BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

248 related articles for article (PubMed ID: 31450087)

  • 1. Inhibition of APE1-endonuclease activity affects cell metabolism in colon cancer cells via a p53-dependent pathway.
    Codrich M; Comelli M; Malfatti MC; Mio C; Ayyildiz D; Zhang C; Kelley MR; Terrosu G; Pucillo CEM; Tell G
    DNA Repair (Amst); 2019 Oct; 82():102675. PubMed ID: 31450087
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of the human AP-endonuclease (APE1/Ref-1) expression by the tumor suppressor p53 in response to DNA damage.
    Zaky A; Busso C; Izumi T; Chattopadhyay R; Bassiouny A; Mitra S; Bhakat KK
    Nucleic Acids Res; 2008 Mar; 36(5):1555-66. PubMed ID: 18208837
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Diverse small molecule inhibitors of human apurinic/apyrimidinic endonuclease APE1 identified from a screen of a large public collection.
    Dorjsuren D; Kim D; Vyjayanti VN; Maloney DJ; Jadhav A; Wilson DM; Simeonov A
    PLoS One; 2012; 7(10):e47974. PubMed ID: 23110144
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel chemopreventive mechanism of selenomethionine: enhancement of APE1 enzyme activity via a Gadd45a, PCNA and APE1 protein complex that regulates p53-mediated base excision repair.
    Jung HJ; Kim HL; Kim YJ; Weon JI; Seo YR
    Oncol Rep; 2013 Oct; 30(4):1581-6. PubMed ID: 23846616
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibitors of the apurinic/apyrimidinic endonuclease 1 (APE1)/nucleophosmin (NPM1) interaction that display anti-tumor properties.
    Poletto M; Malfatti MC; Dorjsuren D; Scognamiglio PL; Marasco D; Vascotto C; Jadhav A; Maloney DJ; Wilson DM; Simeonov A; Tell G
    Mol Carcinog; 2016 May; 55(5):688-704. PubMed ID: 25865359
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of the human apurinic/apyrimidinic endonuclease (APE1) repair activity and sensitization of breast cancer cells to DNA alkylating agents with lucanthone.
    Luo M; Kelley MR
    Anticancer Res; 2004; 24(4):2127-34. PubMed ID: 15330152
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibitors of nuclease and redox activity of apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1).
    Laev SS; Salakhutdinov NF; Lavrik OI
    Bioorg Med Chem; 2017 May; 25(9):2531-2544. PubMed ID: 28161249
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nucleophosmin modulates stability, activity, and nucleolar accumulation of base excision repair proteins.
    Poletto M; Lirussi L; Wilson DM; Tell G
    Mol Biol Cell; 2014 May; 25(10):1641-52. PubMed ID: 24648491
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology.
    Vascotto C; Lirussi L; Poletto M; Tiribelli M; Damiani D; Fabbro D; Damante G; Demple B; Colombo E; Tell G
    Oncogene; 2014 May; 33(22):2876-87. PubMed ID: 23831574
    [TBL] [Abstract][Full Text] [Related]  

  • 10. APE1 and NPM1 protect cancer cells from platinum compounds cytotoxicity and their expression pattern has a prognostic value in TNBC.
    Malfatti MC; Gerratana L; Dalla E; Isola M; Damante G; Di Loreto C; Puglisi F; Tell G
    J Exp Clin Cancer Res; 2019 Jul; 38(1):309. PubMed ID: 31307523
    [TBL] [Abstract][Full Text] [Related]  

  • 11. APE1/Ref-1 enhances DNA binding activity of mutant p53 in a redox-dependent manner.
    Cun Y; Dai N; Li M; Xiong C; Zhang Q; Sui J; Qian C; Wang D
    Oncol Rep; 2014 Feb; 31(2):901-9. PubMed ID: 24297337
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nucleophosmin interaction with APE1: Insights into DNA repair regulation.
    López DJ; de Blas A; Hurtado M; García-Alija M; Mentxaka J; de la Arada I; Urbaneja MA; Alonso-Mariño M; Bañuelos S
    DNA Repair (Amst); 2020 Apr; 88():102809. PubMed ID: 32092641
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthetic lethal targeting of DNA double-strand break repair deficient cells by human apurinic/apyrimidinic endonuclease inhibitors.
    Sultana R; McNeill DR; Abbotts R; Mohammed MZ; Zdzienicka MZ; Qutob H; Seedhouse C; Laughton CA; Fischer PM; Patel PM; Wilson DM; Madhusudan S
    Int J Cancer; 2012 Nov; 131(10):2433-44. PubMed ID: 22377908
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel small-molecule inhibitor of apurinic/apyrimidinic endonuclease 1 blocks proliferation and reduces viability of glioblastoma cells.
    Bapat A; Glass LS; Luo M; Fishel ML; Long EC; Georgiadis MM; Kelley MR
    J Pharmacol Exp Ther; 2010 Sep; 334(3):988-98. PubMed ID: 20504914
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dual regulatory roles of human AP-endonuclease (APE1/Ref-1) in CDKN1A/p21 expression.
    Sengupta S; Mitra S; Bhakat KK
    PLoS One; 2013; 8(7):e68467. PubMed ID: 23874636
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Distinct roles of Ape1 protein in the repair of DNA damage induced by ionizing radiation or bleomycin.
    Fung H; Demple B
    J Biol Chem; 2011 Feb; 286(7):4968-77. PubMed ID: 21081487
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.
    Antoniali G; Serra F; Lirussi L; Tanaka M; D'Ambrosio C; Zhang S; Radovic S; Dalla E; Ciani Y; Scaloni A; Li M; Piazza S; Tell G
    Nat Commun; 2017 Oct; 8(1):797. PubMed ID: 28986522
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacophore guided discovery of small-molecule human apurinic/apyrimidinic endonuclease 1 inhibitors.
    Zawahir Z; Dayam R; Deng J; Pereira C; Neamati N
    J Med Chem; 2009 Jan; 52(1):20-32. PubMed ID: 19072053
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Functional analysis of the involvement of apurinic/apyrimidinic endonuclease 1 in the resistance to melphalan in multiple myeloma.
    Xie J; Zhang L; Li M; Du J; Zhou L; Yang S; Zeng L; Li Z; Wang G; Wang D
    BMC Cancer; 2014 Jan; 14():11. PubMed ID: 24400589
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Endonuclease and redox activities of human apurinic/apyrimidinic endonuclease 1 have distinctive and essential functions in IgA class switch recombination.
    Frossi B; Antoniali G; Yu K; Akhtar N; Kaplan MH; Kelley MR; Tell G; Pucillo CEM
    J Biol Chem; 2019 Mar; 294(13):5198-5207. PubMed ID: 30705092
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.