BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

258 related articles for article (PubMed ID: 31450087)

  • 21. Molecular Mechanisms Regulating the DNA Repair Protein APE1: A Focus on Its Flexible N-Terminal Tail Domain.
    López DJ; Rodríguez JA; Bañuelos S
    Int J Mol Sci; 2021 Jun; 22(12):. PubMed ID: 34208390
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Genetic and biochemical characterization of human AP endonuclease 1 mutants deficient in nucleotide incision repair activity.
    Gelin A; Redrejo-Rodríguez M; Laval J; Fedorova OS; Saparbaev M; Ishchenko AA
    PLoS One; 2010 Aug; 5(8):e12241. PubMed ID: 20808930
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice.
    Unnikrishnan A; Raffoul JJ; Patel HV; Prychitko TM; Anyangwe N; Meira LB; Friedberg EC; Cabelof DC; Heydari AR
    Free Radic Biol Med; 2009 Jun; 46(11):1488-99. PubMed ID: 19268524
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Oxidative DNA damage is concurrently repaired by base excision repair (BER) and apyrimidinic endonuclease 1 (APE1)-initiated nonhomologous end joining (NHEJ) in cortical neurons.
    Yang JL; Chen WY; Mukda S; Yang YR; Sun SF; Chen SD
    Neuropathol Appl Neurobiol; 2020 Jun; 46(4):375-390. PubMed ID: 31628877
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Development and evaluation of human AP endonuclease inhibitors in melanoma and glioma cell lines.
    Mohammed MZ; Vyjayanti VN; Laughton CA; Dekker LV; Fischer PM; Wilson DM; Abbotts R; Shah S; Patel PM; Hickson ID; Madhusudan S
    Br J Cancer; 2011 Feb; 104(4):653-63. PubMed ID: 21266972
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Small-molecule inhibitors of APE1 DNA repair function: an overview.
    Al-Safi RI; Odde S; Shabaik Y; Neamati N
    Curr Mol Pharmacol; 2012 Jan; 5(1):14-35. PubMed ID: 22122462
    [TBL] [Abstract][Full Text] [Related]  

  • 27. SIRT1 deacetylates APE1 and regulates cellular base excision repair.
    Yamamori T; DeRicco J; Naqvi A; Hoffman TA; Mattagajasingh I; Kasuno K; Jung SB; Kim CS; Irani K
    Nucleic Acids Res; 2010 Jan; 38(3):832-45. PubMed ID: 19934257
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Conformational Rearrangements Regulating the DNA Repair Protein APE1.
    Komaniecka N; Porras M; Cairn L; Santas JA; Ferreiro N; Penedo JC; Bañuelos S
    Int J Mol Sci; 2022 Jul; 23(14):. PubMed ID: 35887361
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The role of the N-terminal domain of human apurinic/apyrimidinic endonuclease 1, APE1, in DNA glycosylase stimulation.
    Kladova OA; Bazlekowa-Karaban M; Baconnais S; Piétrement O; Ishchenko AA; Matkarimov BT; Iakovlev DA; Vasenko A; Fedorova OS; Le Cam E; Tudek B; Kuznetsov NA; Saparbaev M
    DNA Repair (Amst); 2018 Apr; 64():10-25. PubMed ID: 29475157
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Knock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and function.
    Vascotto C; Bisetto E; Li M; Zeef LA; D'Ambrosio C; Domenis R; Comelli M; Delneri D; Scaloni A; Altieri F; Mavelli I; Quadrifoglio F; Kelley MR; Tell G
    Mol Biol Cell; 2011 Oct; 22(20):3887-901. PubMed ID: 21865600
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Cytoplasmic Ape1 expression elevated by p53 aberration may predict survival and relapse in resected non-small cell lung cancer.
    Wu HH; Chu YC; Wang L; Tsai LH; Lee MC; Chen CY; Shieh SH; Cheng YW; Lee H
    Ann Surg Oncol; 2013 Dec; 20 Suppl 3():S336-47. PubMed ID: 22688662
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Nuclear depletion of apurinic/apyrimidinic endonuclease 1 (Ape1/Ref-1) is an indicator of energy disruption in neurons.
    Singh S; Englander EW
    Free Radic Biol Med; 2012 Nov; 53(9):1782-90. PubMed ID: 22841870
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Isolation of a small molecule inhibitor of DNA base excision repair.
    Madhusudan S; Smart F; Shrimpton P; Parsons JL; Gardiner L; Houlbrook S; Talbot DC; Hammonds T; Freemont PA; Sternberg MJ; Dianov GL; Hickson ID
    Nucleic Acids Res; 2005; 33(15):4711-24. PubMed ID: 16113242
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Ubiquitination of mammalian AP endonuclease (APE1) regulated by the p53-MDM2 signaling pathway.
    Busso CS; Iwakuma T; Izumi T
    Oncogene; 2009 Apr; 28(13):1616-25. PubMed ID: 19219073
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Design and synthesis of novel quinone inhibitors targeted to the redox function of apurinic/apyrimidinic endonuclease 1/redox enhancing factor-1 (Ape1/ref-1).
    Nyland RL; Luo M; Kelley MR; Borch RF
    J Med Chem; 2010 Feb; 53(3):1200-10. PubMed ID: 20067291
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Tumor-associated APE1 variant exhibits reduced complementation efficiency but does not promote cancer cell phenotypes.
    Illuzzi JL; McNeill DR; Bastian P; Brenerman B; Wersto R; Russell HR; Bunz F; McKinnon PJ; Becker KG; Wilson DM
    Environ Mol Mutagen; 2017 Mar; 58(2):84-98. PubMed ID: 28181292
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Functional analysis of tanshinone IIA that blocks the redox function of human apurinic/apyrimidinic endonuclease 1/redox factor-1.
    Sui J; Li M; Qian C; Wang S; Cheng Y; Chen BP; Wang D
    Drug Des Devel Ther; 2014; 8():2147-60. PubMed ID: 25395832
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Design and synthesis of 3-carbamoylbenzoic acid derivatives as inhibitors of human apurinic/apyrimidinic endonuclease 1 (APE1).
    Aiello F; Shabaik Y; Esqueda A; Sanchez TW; Grande F; Garofalo A; Neamati N
    ChemMedChem; 2012 Oct; 7(10):1825-39. PubMed ID: 22952012
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The redox function of apurinic/apyrimidinic endonuclease 1 as key modulator in photodynamic therapy.
    Franchi LP; de Freitas Lima JEB; Piva HL; Tedesco AC
    J Photochem Photobiol B; 2020 Oct; 211():111992. PubMed ID: 32805556
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synthesis, biological evaluation, and structure-activity relationships of a novel class of apurinic/apyrimidinic endonuclease 1 inhibitors.
    Rai G; Vyjayanti VN; Dorjsuren D; Simeonov A; Jadhav A; Wilson DM; Maloney DJ
    J Med Chem; 2012 Apr; 55(7):3101-12. PubMed ID: 22455312
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.