206 related articles for article (PubMed ID: 31451509)
1. Targeting plasma membrane phosphatidylserine content to inhibit oncogenic KRAS function.
Kattan WE; Chen W; Ma X; Lan TH; van der Hoeven D; van der Hoeven R; Hancock JF
Life Sci Alliance; 2019 Oct; 2(5):. PubMed ID: 31451509
[TBL] [Abstract][Full Text] [Related]
2. Components of the phosphatidylserine endoplasmic reticulum to plasma membrane transport mechanism as targets for KRAS inhibition in pancreatic cancer.
Kattan WE; Liu J; Montufar-Solis D; Liang H; Brahmendra Barathi B; van der Hoeven R; Zhou Y; Hancock JF
Proc Natl Acad Sci U S A; 2021 Dec; 118(51):. PubMed ID: 34903667
[TBL] [Abstract][Full Text] [Related]
3. ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P
Ghai R; Du X; Wang H; Dong J; Ferguson C; Brown AJ; Parton RG; Wu JW; Yang H
Nat Commun; 2017 Oct; 8(1):757. PubMed ID: 28970484
[TBL] [Abstract][Full Text] [Related]
4. INTRACELLULAR TRANSPORT. PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts.
Chung J; Torta F; Masai K; Lucast L; Czapla H; Tanner LB; Narayanaswamy P; Wenk MR; Nakatsu F; De Camilli P
Science; 2015 Jul; 349(6246):428-32. PubMed ID: 26206935
[TBL] [Abstract][Full Text] [Related]
5. PtdSer as a signaling lipid determined by privileged localization of ORP5 and ORP8 at ER/PM junctional foci to determine PM and ER PtdSer/PI(4)P ratio and cell function.
Chung WY; Ahuja M; McNally BA; Leibow SR; Ohman HKE; Movahed Abtahi A; Muallem S
Proc Natl Acad Sci U S A; 2023 Aug; 120(35):e2301410120. PubMed ID: 37607230
[TBL] [Abstract][Full Text] [Related]
6. PI(4,5)P
Sohn M; Korzeniowski M; Zewe JP; Wills RC; Hammond GRV; Humpolickova J; Vrzal L; Chalupska D; Veverka V; Fairn GD; Boura E; Balla T
J Cell Biol; 2018 May; 217(5):1797-1813. PubMed ID: 29472386
[TBL] [Abstract][Full Text] [Related]
7. ORP5/ORP8 localize to endoplasmic reticulum-mitochondria contacts and are involved in mitochondrial function.
Galmes R; Houcine A; van Vliet AR; Agostinis P; Jackson CL; Giordano F
EMBO Rep; 2016 Jun; 17(6):800-10. PubMed ID: 27113756
[TBL] [Abstract][Full Text] [Related]
8. Myotubularin-related proteins regulate KRAS function by controlling plasma membrane levels of polyphosphoinositides and phosphatidylserine.
Henkels KM; Miller TE; Naji A; van der Hoeven R; Liang H; Zhou Y; Hammond GRV; Hancock JF; Cho KJ
bioRxiv; 2024 Jan; ():. PubMed ID: 38328115
[TBL] [Abstract][Full Text] [Related]
9. Oncogenic KRAS is dependent upon an EFR3A-PI4KA signaling axis for potent tumorigenic activity.
Adhikari H; Kattan WE; Kumar S; Zhou P; Hancock JF; Counter CM
Nat Commun; 2021 Sep; 12(1):5248. PubMed ID: 34504076
[TBL] [Abstract][Full Text] [Related]
10. Acylpeptide hydrolase is a novel regulator of KRAS plasma membrane localization and function.
Tan L; Cho KJ; Kattan WE; Garrido CM; Zhou Y; Neupane P; Capon RJ; Hancock JF
J Cell Sci; 2019 Jul; 132(15):. PubMed ID: 31266814
[TBL] [Abstract][Full Text] [Related]
11. An oxanthroquinone derivative that disrupts RAS plasma membrane localization inhibits cancer cell growth.
Tan L; Cho KJ; Neupane P; Capon RJ; Hancock JF
J Biol Chem; 2018 Aug; 293(35):13696-13706. PubMed ID: 29970615
[TBL] [Abstract][Full Text] [Related]
12. Depletion of phosphatidylinositol 4-phosphate at the Golgi translocates K-Ras to mitochondria.
Miller TE; Henkels KM; Huddleston M; Salisbury R; Hussain SM; Sasaki AT; Cho KJ
J Cell Sci; 2019 Aug; 132(16):. PubMed ID: 31331963
[TBL] [Abstract][Full Text] [Related]
13. Oxysterol-binding protein-related protein 5 (ORP5) promotes cell proliferation by activation of mTORC1 signaling.
Du X; Zadoorian A; Lukmantara IE; Qi Y; Brown AJ; Yang H
J Biol Chem; 2018 Mar; 293(10):3806-3818. PubMed ID: 29358326
[TBL] [Abstract][Full Text] [Related]
14. ORP5 and ORP8: Sterol Sensors and Phospholipid Transfer Proteins at Membrane Contact Sites?
Santos NC; Girik V; Nunes-Hasler P
Biomolecules; 2020 Jun; 10(6):. PubMed ID: 32570981
[TBL] [Abstract][Full Text] [Related]
15. The KRAS and other prenylated polybasic domain membrane anchors recognize phosphatidylserine acyl chain structure.
Zhou Y; Prakash PS; Liang H; Gorfe AA; Hancock JF
Proc Natl Acad Sci U S A; 2021 Feb; 118(6):. PubMed ID: 33526670
[TBL] [Abstract][Full Text] [Related]
16. Quantitative biophysical analysis defines key components modulating recruitment of the GTPase KRAS to the plasma membrane.
Lakshman B; Messing S; Schmid EM; Clogston JD; Gillette WK; Esposito D; Kessing B; Fletcher DA; Nissley DV; McCormick F; Stephen AG; Jean-Francois FL
J Biol Chem; 2019 Feb; 294(6):2193-2207. PubMed ID: 30559287
[TBL] [Abstract][Full Text] [Related]
17. Oncogenic KRAS drives radioresistance through upregulation of NRF2-53BP1-mediated non-homologous end-joining repair.
Yang L; Shen C; Estrada-Bernal A; Robb R; Chatterjee M; Sebastian N; Webb A; Mo X; Chen W; Krishnan S; Williams TM
Nucleic Acids Res; 2021 Nov; 49(19):11067-11082. PubMed ID: 34606602
[TBL] [Abstract][Full Text] [Related]
18. Oxysterol-binding protein related-proteins (ORPs) 5 and 8 regulate calcium signaling at specific cell compartments.
Pulli I; Lassila T; Pan G; Yan D; Olkkonen VM; Törnquist K
Cell Calcium; 2018 Jun; 72():62-69. PubMed ID: 29748134
[TBL] [Abstract][Full Text] [Related]
19. The G protein-coupled receptor GPR31 promotes membrane association of KRAS.
Fehrenbacher N; Tojal da Silva I; Ramirez C; Zhou Y; Cho KJ; Kuchay S; Shi J; Thomas S; Pagano M; Hancock JF; Bar-Sagi D; Philips MR
J Cell Biol; 2017 Aug; 216(8):2329-2338. PubMed ID: 28619714
[TBL] [Abstract][Full Text] [Related]
20. A novel prenyl-polybasic domain code determines lipid-binding specificity of the K-Ras membrane anchor.
Zhou Y; Hancock JF
Small GTPases; 2020 May; 11(3):220-224. PubMed ID: 29239694
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]