These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 31452440)

  • 1. New heat shock protein (Hsp90) inhibitors, designed by pharmacophore modeling and virtual screening: synthesis, biological evaluation and molecular dynamics studies.
    Abbasi M; Amanlou M; Aghaei M; Bakherad M; Doosti R; Sadeghi-Aliabadi H
    J Biomol Struct Dyn; 2020 Aug; 38(12):3462-3473. PubMed ID: 31452440
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of New Hsp90 Inhibitors: Structure Based Virtual Screening, Molecular Dynamic Simulation, Synthesis and Biological Evaluation.
    Abbasi M; Amanlou M; Aghaei M; Hassanzadeh F; Sadeghi-Aliabadi H
    Anticancer Agents Med Chem; 2021; 21(18):2583-2591. PubMed ID: 33563187
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Quinazoline Based HSP90 Inhibitors: Synthesis, Modeling Study and ADME Calculations Towards Breast Cancer Targeting.
    El-Shafey HW; Gomaa RM; El-Messery SM; Goda FE
    Bioorg Med Chem Lett; 2020 Aug; 30(15):127281. PubMed ID: 32527460
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-based virtual screening and optimization of modulators targeting Hsp90-Cdc37 interaction.
    Wang L; Li L; Zhou ZH; Jiang ZY; You QD; Xu XL
    Eur J Med Chem; 2017 Aug; 136():63-73. PubMed ID: 28482218
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, and molecular docking studies of novel pyrazolyl 2-aminopyrimidine derivatives as HSP90 inhibitors.
    Mettu A; Talla V; Bajaj DM; Subhashini NJP
    Arch Pharm (Weinheim); 2019 Oct; 352(10):e1900063. PubMed ID: 31411362
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and biological evaluation of 7-(aryl)-2,3-dihydro-[1,4]dioxino[2,3-g]quinoline derivatives as potential Hsp90 inhibitors and anticancer agents.
    Malayeri SO; Abnous K; Arab A; Akaberi M; Mehri S; Zarghi A; Ghodsi R
    Bioorg Med Chem; 2017 Feb; 25(3):1294-1302. PubMed ID: 28073608
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of potent heat shock protein 90 (Hsp90) inhibitors: structure-based virtual screening, molecular dynamics simulation, and biological evaluation.
    Xu Y; Zou Y; Zhou S; Niu MM; Zhang Y; Li J; Xu Z; Yang L
    J Enzyme Inhib Med Chem; 2023 Dec; 38(1):2220558. PubMed ID: 37357755
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification, design and bio-evaluation of novel Hsp90 inhibitors by ligand-based virtual screening.
    Jia J; Xu X; Liu F; Guo X; Zhang M; Lu M; Xu L; Wei J; Zhu J; Zhang S; Zhang S; Sun H; You Q
    PLoS One; 2013; 8(4):e59315. PubMed ID: 23565147
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prediction of new Hsp90 inhibitors based on 3,4-isoxazolediamide scaffold using QSAR study, molecular docking and molecular dynamic simulation.
    Abbasi M; Sadeghi-Aliabadi H; Amanlou M
    Daru; 2017 Jun; 25(1):17. PubMed ID: 28666484
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of Novel Hsp90 C-Terminal Inhibitors Using 3D-Pharmacophores Derived from Molecular Dynamics Simulations.
    Tomašič T; Durcik M; Keegan BM; Skledar DG; Zajec Ž; Blagg BSJ; Bryant SD
    Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32962253
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of 2,4-diaminoquinazoline derivatives as novel heat shock protein 90 inhibitors.
    Thorat DA; Doddareddy MR; Seo SH; Hong TJ; Cho YS; Hahn JS; Pae AN
    Bioorg Med Chem Lett; 2011 Mar; 21(6):1593-7. PubMed ID: 21353544
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Fe
    Maddela S; Makula A; Galigniana MD; Parambi DGT; Federicci F; Mazaira G; Hendawy OM; Dev S; Mathew GE; Mathew B
    Arch Pharm (Weinheim); 2019 Jan; 352(1):e1800174. PubMed ID: 30485473
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, Synthesis, and Evaluation of Heat Shock Protein 90 Inhibitors in Human Breast Cancer and Its Metastasis.
    Gümus M; Ozgur A; Tutar L; Disli A; Koca I; Tutar Y
    Curr Pharm Biotechnol; 2016; 17(14):1231-1245. PubMed ID: 27804852
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological activities of a new class of heat shock protein 90 inhibitors, designed by energy-based pharmacophore virtual screening.
    Lauria A; Abbate I; Gentile C; Angileri F; Martorana A; Almerico AM
    J Med Chem; 2013 Apr; 56(8):3424-8. PubMed ID: 23520985
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of 5-aryl-3-thiophen-2-yl-1H-pyrazoles as a new class of Hsp90 inhibitors in hepatocellular carcinoma.
    Mohamady S; Ismail MI; Mogheith SM; Attia YM; Taylor SD
    Bioorg Chem; 2020 Jan; 94():103433. PubMed ID: 31785857
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of Hsp90.
    Shin SC; El-Damasy AK; Lee JH; Seo SH; Kim JH; Seo YH; Lee Y; Yu JH; Bang EK; Kim EE; Keum G
    Int J Mol Sci; 2020 Dec; 21(24):. PubMed ID: 33317068
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Virtual screening based identification of miltefosine and octenidine as inhibitors of heat shock protein 90.
    Li L; Yang M; Li C; Liu Y
    Naunyn Schmiedebergs Arch Pharmacol; 2021 Nov; 394(11):2223-2232. PubMed ID: 34406420
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis and pharmacological evaluation of N-(5-chloro-2,4-dihydroxybenzoyl)-(R)-N-arylmethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxamides as potent Hsp90 inhibitors.
    Liang C; Wu X; Li Z; Zhu J; Lu C; Shen Y
    Eur J Med Chem; 2018 Jan; 143():85-96. PubMed ID: 29172085
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis, and biological evaluation of a series of resorcinol-based N-benzyl benzamide derivatives as potent Hsp90 inhibitors.
    Park SY; Oh YJ; Lho Y; Jeong JH; Liu KH; Song J; Kim SH; Ha E; Seo YH
    Eur J Med Chem; 2018 Jan; 143():390-401. PubMed ID: 29202402
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis, and biological evaluation of truncated deguelin derivatives as Hsp90 inhibitors.
    Yao H; Xu F; Wang G; Xie S; Li W; Yao H; Ma C; Zhu Z; Xu J; Xu S
    Eur J Med Chem; 2019 Apr; 167():485-498. PubMed ID: 30784881
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.