These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

211 related articles for article (PubMed ID: 31452509)

  • 1. Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice.
    Tao Y; Mis M; Blazer L; Ustav M; Steinhart Z; Chidiac R; Kubarakos E; O'Brien S; Wang X; Jarvik N; Patel N; Adams J; Moffat J; Angers S; Sidhu SS
    Elife; 2019 Aug; 8():. PubMed ID: 31452509
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling.
    Janda CY; Dang LT; You C; Chang J; de Lau W; Zhong ZA; Yan KS; Marecic O; Siepe D; Li X; Moody JD; Williams BO; Clevers H; Piehler J; Baker D; Kuo CJ; Garcia KC
    Nature; 2017 May; 545(7653):234-237. PubMed ID: 28467818
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development of Potent, Selective Surrogate WNT Molecules and Their Application in Defining Frizzled Requirements.
    Chen H; Lu C; Ouyang B; Zhang H; Huang Z; Bhatia D; Lee SJ; Shah D; Sura A; Yeh WC; Li Y
    Cell Chem Biol; 2020 May; 27(5):598-609.e4. PubMed ID: 32220333
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo.
    Miao Y; Ha A; de Lau W; Yuki K; Santos AJM; You C; Geurts MH; Puschhof J; Pleguezuelos-Manzano C; Peng WC; Senlice R; Piani C; Buikema JW; Gbenedio OM; Vallon M; Yuan J; de Haan S; Hemrika W; Rösch K; Dang LT; Baker D; Ott M; Depeille P; Wu SM; Drost J; Nusse R; Roose JP; Piehler J; Boj SF; Janda CY; Clevers H; Kuo CJ; Garcia KC
    Cell Stem Cell; 2020 Nov; 27(5):840-851.e6. PubMed ID: 32818433
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Oligomerization of Frizzled and LRP5/6 protein initiates intracellular signaling for the canonical WNT/β-catenin pathway.
    Hua Y; Yang Y; Li Q; He X; Zhu W; Wang J; Gan X
    J Biol Chem; 2018 Dec; 293(51):19710-19724. PubMed ID: 30361437
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Infection-induced signals generated at the plasma membrane epigenetically regulate Wnt signaling
    Ahmed I; Roy BC; Rao Jakkula LUM; Subramaniam D; Dandawate P; Anant S; Sampath V; Umar S
    J Biol Chem; 2020 Jan; 295(4):1021-1035. PubMed ID: 31836665
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling.
    Holmen SL; Salic A; Zylstra CR; Kirschner MW; Williams BO
    J Biol Chem; 2002 Sep; 277(38):34727-35. PubMed ID: 12121999
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Distinct roles of LRP5 and LRP6 in Wnt signaling regulation in the retina.
    Singh HD; Ma JX; Takahashi Y
    Biochem Biophys Res Commun; 2021 Mar; 545():8-13. PubMed ID: 33545636
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins.
    Brennan K; Gonzalez-Sancho JM; Castelo-Soccio LA; Howe LR; Brown AM
    Oncogene; 2004 Jun; 23(28):4873-84. PubMed ID: 15064719
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Both LRP5 and LRP6 receptors are required to respond to physiological Wnt ligands in mammary epithelial cells and fibroblasts.
    Goel S; Chin EN; Fakhraldeen SA; Berry SM; Beebe DJ; Alexander CM
    J Biol Chem; 2012 May; 287(20):16454-66. PubMed ID: 22433869
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel Frizzled-specific antibody-based Wnt mimetics and Wnt superagonists selectively activate WNT/β-catenin signaling in target tissues.
    Post Y; Dilip A; Xie L; Sura A; Suen N; Ye J; Mutha D; Liu AT; Nguyen H; Whisler E; Shah D; Deshmukh S; Dhaliwal N; Bauer B; Nigatu E; Diep A; Lopez T; Fowler TW; Lee SJ; Lu C; Yeh WC; Chen H; Li Y
    Cell Chem Biol; 2023 Aug; 30(8):976-986.e5. PubMed ID: 37413985
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for coreceptor discrimination.
    Tsutsumi N; Hwang S; Waghray D; Hansen S; Jude KM; Wang N; Miao Y; Glassman CR; Caveney NA; Janda CY; Hannoush RN; Garcia KC
    Proc Natl Acad Sci U S A; 2023 Mar; 120(11):e2218238120. PubMed ID: 36893265
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of Wnt Signaling Increases Numbers of Enteric Neurons Derived From Neonatal Mouse and Human Progenitor Cells.
    Zhang Y; Seid K; Obermayr F; Just L; Neckel PH
    Gastroenterology; 2017 Jul; 153(1):154-165.e9. PubMed ID: 28359679
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Frizzled and LRP5/6 receptors for Wnt/β-catenin signaling.
    MacDonald BT; He X
    Cold Spring Harb Perspect Biol; 2012 Dec; 4(12):. PubMed ID: 23209147
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells.
    Gumber D; Do M; Suresh Kumar N; Sonavane PR; Wu CCN; Cruz LS; Grainger S; Carson D; Gaasterland T; Willert K
    Elife; 2020 Dec; 9():. PubMed ID: 33331818
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5.
    Wang Z; Shu W; Lu MM; Morrisey EE
    Mol Cell Biol; 2005 Jun; 25(12):5022-30. PubMed ID: 15923619
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of Wnt/β-catenin signaling by a soluble collagen-derived frizzled domain interacting with Wnt3a and the receptors frizzled 1 and 8.
    Hendaoui I; Lavergne E; Lee HS; Hong SH; Kim HZ; Parent C; Heuzé-Vourc'h N; Clément B; Musso O
    PLoS One; 2012; 7(1):e30601. PubMed ID: 22303445
    [TBL] [Abstract][Full Text] [Related]  

  • 18. LRPs in WNT Signalling.
    Davidson G
    Handb Exp Pharmacol; 2021; 269():45-73. PubMed ID: 34490514
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A role for Wnt/beta-catenin signaling in lens epithelial differentiation.
    Stump RJ; Ang S; Chen Y; von Bahr T; Lovicu FJ; Pinson K; de Iongh RU; Yamaguchi TP; Sassoon DA; McAvoy JW
    Dev Biol; 2003 Jul; 259(1):48-61. PubMed ID: 12812787
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells.
    Fenderico N; van Scherpenzeel RC; Goldflam M; Proverbio D; Jordens I; Kralj T; Stryeck S; Bass TZ; Hermans G; Ullman C; Aastrup T; Gros P; Maurice MM
    Nat Commun; 2019 Jan; 10(1):365. PubMed ID: 30664649
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.