180 related articles for article (PubMed ID: 31455522)
1. Measuring TREX1 and TREX2 exonuclease activities.
Hemphill WO; Perrino FW
Methods Enzymol; 2019; 625():109-133. PubMed ID: 31455522
[TBL] [Abstract][Full Text] [Related]
2. The TREX1 double-stranded DNA degradation activity is defective in dominant mutations associated with autoimmune disease.
Lehtinen DA; Harvey S; Mulcahy MJ; Hollis T; Perrino FW
J Biol Chem; 2008 Nov; 283(46):31649-56. PubMed ID: 18805785
[TBL] [Abstract][Full Text] [Related]
3. Dominant mutation of the TREX1 exonuclease gene in lupus and Aicardi-Goutieres syndrome.
Fye JM; Orebaugh CD; Coffin SR; Hollis T; Perrino FW
J Biol Chem; 2011 Sep; 286(37):32373-82. PubMed ID: 21808053
[TBL] [Abstract][Full Text] [Related]
4. The TREX1 exonuclease R114H mutation in Aicardi-Goutières syndrome and lupus reveals dimeric structure requirements for DNA degradation activity.
Orebaugh CD; Fye JM; Harvey S; Hollis T; Perrino FW
J Biol Chem; 2011 Nov; 286(46):40246-54. PubMed ID: 21937424
[TBL] [Abstract][Full Text] [Related]
5. The Arg-62 residues of the TREX1 exonuclease act across the dimer interface contributing to catalysis in the opposing protomers.
Fye JM; Coffin SR; Orebaugh CD; Hollis T; Perrino FW
J Biol Chem; 2014 Apr; 289(16):11556-11565. PubMed ID: 24616097
[TBL] [Abstract][Full Text] [Related]
6. Biochemical properties of mammalian TREX1 and its association with DNA replication and inherited inflammatory disease.
Lindahl T; Barnes DE; Yang YG; Robins P
Biochem Soc Trans; 2009 Jun; 37(Pt 3):535-8. PubMed ID: 19442247
[TBL] [Abstract][Full Text] [Related]
7. Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease.
Grieves JL; Fye JM; Harvey S; Grayson JM; Hollis T; Perrino FW
Proc Natl Acad Sci U S A; 2015 Apr; 112(16):5117-22. PubMed ID: 25848017
[TBL] [Abstract][Full Text] [Related]
8. DNase-active TREX1 frame-shift mutants induce serologic autoimmunity in mice.
Sakai T; Miyazaki T; Shin DM; Kim YS; Qi CF; Fariss R; Munasinghe J; Wang H; Kovalchuk AL; Kothari PH; Fermaintt CS; Atkinson JP; Perrino FW; Yan N; Morse HC
J Autoimmun; 2017 Jul; 81():13-23. PubMed ID: 28325644
[TBL] [Abstract][Full Text] [Related]
9. Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.
Lee-Kirsch MA; Gong M; Chowdhury D; Senenko L; Engel K; Lee YA; de Silva U; Bailey SL; Witte T; Vyse TJ; Kere J; Pfeiffer C; Harvey S; Wong A; Koskenmies S; Hummel O; Rohde K; Schmidt RE; Dominiczak AF; Gahr M; Hollis T; Perrino FW; Lieberman J; Hübner N
Nat Genet; 2007 Sep; 39(9):1065-7. PubMed ID: 17660818
[TBL] [Abstract][Full Text] [Related]
10. Aicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion.
Li P; Du J; Goodier JL; Hou J; Kang J; Kazazian HH; Zhao K; Yu XF
Nucleic Acids Res; 2017 May; 45(8):4619-4631. PubMed ID: 28334850
[TBL] [Abstract][Full Text] [Related]
11. Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome.
Rice G; Newman WG; Dean J; Patrick T; Parmar R; Flintoff K; Robins P; Harvey S; Hollis T; O'Hara A; Herrick AL; Bowden AP; Perrino FW; Lindahl T; Barnes DE; Crow YJ
Am J Hum Genet; 2007 Apr; 80(4):811-5. PubMed ID: 17357087
[TBL] [Abstract][Full Text] [Related]
12. The TREX1 C-terminal region controls cellular localization through ubiquitination.
Orebaugh CD; Fye JM; Harvey S; Hollis T; Wilkinson JC; Perrino FW
J Biol Chem; 2013 Oct; 288(40):28881-92. PubMed ID: 23979357
[TBL] [Abstract][Full Text] [Related]
13. A homozygote TREX1 mutation in two siblings with different phenotypes: Chilblains and cerebral vasculitis.
Kisla Ekinci RM; Balci S; Bisgin A; Altintas DU; Yilmaz M
Eur J Med Genet; 2017 Dec; 60(12):690-694. PubMed ID: 28919362
[TBL] [Abstract][Full Text] [Related]
14. TREX1 - Apex predator of cytosolic DNA metabolism.
Simpson SR; Hemphill WO; Hudson T; Perrino FW
DNA Repair (Amst); 2020 Oct; 94():102894. PubMed ID: 32615442
[TBL] [Abstract][Full Text] [Related]
15. Defects in DNA degradation revealed in crystal structures of TREX1 exonuclease mutations linked to autoimmune disease.
Bailey SL; Harvey S; Perrino FW; Hollis T
DNA Repair (Amst); 2012 Jan; 11(1):65-73. PubMed ID: 22071149
[TBL] [Abstract][Full Text] [Related]
16. Human Three Prime Repair Exonuclease 1 Promotes HIV-1 Integration by Preferentially Degrading Unprocessed Viral DNA.
Davids BO; Balasubramaniam M; Sapp N; Prakash P; Ingram S; Li M; Craigie R; Hollis T; Pandhare J; Dash C
J Virol; 2021 Aug; 95(17):e0055521. PubMed ID: 34105995
[TBL] [Abstract][Full Text] [Related]
17. Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi-Goutières Syndrome.
Gray EE; Treuting PM; Woodward JJ; Stetson DB
J Immunol; 2015 Sep; 195(5):1939-43. PubMed ID: 26223655
[TBL] [Abstract][Full Text] [Related]
18. Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease.
Yang YG; Lindahl T; Barnes DE
Cell; 2007 Nov; 131(5):873-86. PubMed ID: 18045533
[TBL] [Abstract][Full Text] [Related]
19. Genotype-Phenotype Correlation and Functional Insights for Two Monoallelic
Amico G; Hemphill WO; Severino M; Moratti C; Pascarella R; Bertamino M; Napoli F; Volpi S; Rosamilia F; Signa S; Perrino F; Zedde M; Ceccherini I; On Behalf Of The Gaslini Stroke Study Group
Genes (Basel); 2022 Jun; 13(7):. PubMed ID: 35885962
[TBL] [Abstract][Full Text] [Related]
20. C-terminal truncations in human 3'-5' DNA exonuclease TREX1 cause autosomal dominant retinal vasculopathy with cerebral leukodystrophy.
Richards A; van den Maagdenberg AM; Jen JC; Kavanagh D; Bertram P; Spitzer D; Liszewski MK; Barilla-Labarca ML; Terwindt GM; Kasai Y; McLellan M; Grand MG; Vanmolkot KR; de Vries B; Wan J; Kane MJ; Mamsa H; Schäfer R; Stam AH; Haan J; de Jong PT; Storimans CW; van Schooneveld MJ; Oosterhuis JA; Gschwendter A; Dichgans M; Kotschet KE; Hodgkinson S; Hardy TA; Delatycki MB; Hajj-Ali RA; Kothari PH; Nelson SF; Frants RR; Baloh RW; Ferrari MD; Atkinson JP
Nat Genet; 2007 Sep; 39(9):1068-70. PubMed ID: 17660820
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
