These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

74 related articles for article (PubMed ID: 31455538)

  • 1. A pyrophosphatase-coupled assay to monitor the NTase activity of cGAS.
    Hooy R; Sohn J
    Methods Enzymol; 2019; 625():77-86. PubMed ID: 31455538
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
    Hall J; Ralph EC; Shanker S; Wang H; Byrnes LJ; Horst R; Wong J; Brault A; Dumlao D; Smith JF; Dakin LA; Schmitt DC; Trujillo J; Vincent F; Griffor M; Aulabaugh AE
    Protein Sci; 2017 Dec; 26(12):2367-2380. PubMed ID: 28940468
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Catalytic Promiscuity of cGAS: A Facile Enzymatic Synthesis of 2'-3'-Linked Cyclic Dinucleotides.
    Rosenthal K; Becker M; Rolf J; Siedentop R; Hillen M; Nett M; Lütz S
    Chembiochem; 2020 Nov; 21(22):3225-3228. PubMed ID: 32633874
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay.
    Hall J; Brault A; Vincent F; Weng S; Wang H; Dumlao D; Aulabaugh A; Aivazian D; Castro D; Chen M; Culp J; Dower K; Gardner J; Hawrylik S; Golenbock D; Hepworth D; Horn M; Jones L; Jones P; Latz E; Li J; Lin LL; Lin W; Lin D; Lovering F; Niljanskul N; Nistler R; Pierce B; Plotnikova O; Schmitt D; Shanker S; Smith J; Snyder W; Subashi T; Trujillo J; Tyminski E; Wang G; Wong J; Lefker B; Dakin L; Leach K
    PLoS One; 2017; 12(9):e0184843. PubMed ID: 28934246
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cyclic GMP-AMP synthase is activated by double-stranded DNA-induced oligomerization.
    Li X; Shu C; Yi G; Chaton CT; Shelton CL; Diao J; Zuo X; Kao CC; Herr AB; Li P
    Immunity; 2013 Dec; 39(6):1019-31. PubMed ID: 24332030
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Screening and Identification of Novel cGAS Homologues Using a Combination of in Vitro and In Vivo Protein Synthesis.
    Rolf J; Siedentop R; Lütz S; Rosenthal K
    Int J Mol Sci; 2019 Dec; 21(1):. PubMed ID: 31877895
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The cGAS-cGAMP-STING pathway connects DNA damage to inflammation, senescence, and cancer.
    Li T; Chen ZJ
    J Exp Med; 2018 May; 215(5):1287-1299. PubMed ID: 29622565
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression.
    Lama L; Adura C; Xie W; Tomita D; Kamei T; Kuryavyi V; Gogakos T; Steinberg JI; Miller M; Ramos-Espiritu L; Asano Y; Hashizume S; Aida J; Imaeda T; Okamoto R; Jennings AJ; Michino M; Kuroita T; Stamford A; Gao P; Meinke P; Glickman JF; Patel DJ; Tuschl T
    Nat Commun; 2019 May; 10(1):2261. PubMed ID: 31113940
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development of novel highly sensitive methods to detect endogenous cGAMP in cells and tissue.
    Miyakawa S; Okui T; Shiraishi T; Yoshihara T; Hirayama M; Satomi Y; Hamada T; Nishida M; Akimoto C; Sato S
    J Immunol Methods; 2020 May; 480():112751. PubMed ID: 31982420
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ku proteins promote DNA binding and condensation of cyclic GMP-AMP synthase.
    Tao X; Song J; Song Y; Zhang Y; Yang J; Zhang P; Zhang D; Chen D; Sun Q
    Cell Rep; 2022 Sep; 40(10):111310. PubMed ID: 36070696
    [TBL] [Abstract][Full Text] [Related]  

  • 11. cGAS and CD-NTase enzymes: structure, mechanism, and evolution.
    Kranzusch PJ
    Curr Opin Struct Biol; 2019 Dec; 59():178-187. PubMed ID: 31593902
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mn
    Zhao Z; Ma Z; Wang B; Guan Y; Su XD; Jiang Z
    Cell Rep; 2020 Aug; 32(7):108053. PubMed ID: 32814054
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An E1-E2 fusion protein primes antiviral immune signalling in bacteria.
    Ledvina HE; Ye Q; Gu Y; Sullivan AE; Quan Y; Lau RK; Zhou H; Corbett KD; Whiteley AT
    Nature; 2023 Apr; 616(7956):319-325. PubMed ID: 36755092
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1.
    Kato K; Nishimasu H; Oikawa D; Hirano S; Hirano H; Kasuya G; Ishitani R; Tokunaga F; Nureki O
    Nat Commun; 2018 Oct; 9(1):4424. PubMed ID: 30356045
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery and characterization of a novel cGAS covalent inhibitor for the treatment of inflammatory bowel disease.
    Song J; Yang RR; Chang J; Liu YD; Lu CH; Chen LF; Guo H; Zhang YH; Fan ZS; Zhou JY; Zhou GZ; Zhang KK; Luo XM; Chen KX; Jiang HL; Zhang SL; Zheng MY
    Acta Pharmacol Sin; 2023 Apr; 44(4):791-800. PubMed ID: 36229599
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.
    Gao P; Ascano M; Wu Y; Barchet W; Gaffney BL; Zillinger T; Serganov AA; Liu Y; Jones RA; Hartmann G; Tuschl T; Patel DJ
    Cell; 2013 May; 153(5):1094-107. PubMed ID: 23647843
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression of Cyclic GMP-AMP Synthase in Patients With Systemic Lupus Erythematosus.
    An J; Durcan L; Karr RM; Briggs TA; Rice GI; Teal TH; Woodward JJ; Elkon KB
    Arthritis Rheumatol; 2017 Apr; 69(4):800-807. PubMed ID: 27863149
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An RNA-Based Fluorescent Biosensor for High-Throughput Analysis of the cGAS-cGAMP-STING Pathway.
    Bose D; Su Y; Marcus A; Raulet DH; Hammond MC
    Cell Chem Biol; 2016 Dec; 23(12):1539-1549. PubMed ID: 27889408
    [TBL] [Abstract][Full Text] [Related]  

  • 19. cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders.
    Andreeva L; Hiller B; Kostrewa D; Lässig C; de Oliveira Mann CC; Jan Drexler D; Maiser A; Gaidt M; Leonhardt H; Hornung V; Hopfner KP
    Nature; 2017 Sep; 549(7672):394-398. PubMed ID: 28902841
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Development of cGAMP-Luc, a sensitive and precise coupled enzyme assay to measure cGAMP in complex biological samples.
    Mardjuki RE; Carozza JA; Li L
    J Biol Chem; 2020 Apr; 295(15):4881-4892. PubMed ID: 32127400
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.