BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

358 related articles for article (PubMed ID: 31461190)

  • 1. Adenomatous Polyposis Coli as a Major Regulator of Human Embryonic Stem Cells Self-Renewal.
    Preisler L; Ben-Yosef D; Mayshar Y
    Stem Cells; 2019 Dec; 37(12):1505-1515. PubMed ID: 31461190
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The effect of a germline mutation in the APC gene on β-catenin in human embryonic stem cells.
    Yedid N; Kalma Y; Malcov M; Amit A; Kariv R; Caspi M; Rosin-Arbesfeld R; Ben-Yosef D
    BMC Cancer; 2016 Dec; 16(1):952. PubMed ID: 28010732
    [TBL] [Abstract][Full Text] [Related]  

  • 3. miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4.
    Prossomariti A; Piazzi G; D'Angelo L; Miccoli S; Turchetti D; Alquati C; Montagna C; Bazzoli F; Ricciardiello L
    Mol Cancer Res; 2018 Dec; 16(12):1965-1976. PubMed ID: 30072583
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inactivation of the APC gene is constant in adrenocortical tumors from patients with familial adenomatous polyposis but not frequent in sporadic adrenocortical cancers.
    Gaujoux S; Pinson S; Gimenez-Roqueplo AP; Amar L; Ragazzon B; Launay P; Meatchi T; Libé R; Bertagna X; Audebourg A; Zucman-Rossi J; Tissier F; Bertherat J
    Clin Cancer Res; 2010 Nov; 16(21):5133-41. PubMed ID: 20978149
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Familial adenomatous polyposis syndrome (FAP): pathogenesis and molecular mechanisms].
    Friedrich A; Kullmann F
    Med Klin (Munich); 2003 Dec; 98(12):776-82. PubMed ID: 14685680
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ovarian steroid cell tumor with biallelic adenomatous polyposis coli inactivation in a patient with familial adenomatous polyposis.
    Hu PJ; Knoepp SM; Wu R; Cho KR
    Genes Chromosomes Cancer; 2012 Mar; 51(3):283-9. PubMed ID: 22120905
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Testing models of the APC tumor suppressor/β-catenin interaction reshapes our view of the destruction complex in Wnt signaling.
    Yamulla RJ; Kane EG; Moody AE; Politi KA; Lock NE; Foley AV; Roberts DM
    Genetics; 2014 Aug; 197(4):1285-302. PubMed ID: 24931405
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis.
    Gaspar C; Franken P; Molenaar L; Breukel C; van der Valk M; Smits R; Fodde R
    PLoS Genet; 2009 Jul; 5(7):e1000547. PubMed ID: 19578404
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel read through agent: ZKN-0013 demonstrates efficacy in APC
    Graf MR; Apte S; Terzo E; Padhye S; Shi S; Cox MK; Clark RB; Modur V; Badarinarayana V
    J Mol Med (Berl); 2023 Apr; 101(4):375-385. PubMed ID: 36808265
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Heterozygous APC germline mutations impart predisposition to colorectal cancer.
    Preisler L; Habib A; Shapira G; Kuznitsov-Yanovsky L; Mayshar Y; Carmel-Gross I; Malcov M; Azem F; Shomron N; Kariv R; Hershkovitz D; Ben-Yosef D
    Sci Rep; 2021 Mar; 11(1):5113. PubMed ID: 33664379
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade.
    Albuquerque C; Breukel C; van der Luijt R; Fidalgo P; Lage P; Slors FJ; Leitão CN; Fodde R; Smits R
    Hum Mol Genet; 2002 Jun; 11(13):1549-60. PubMed ID: 12045208
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Contribution of the 15 amino acid repeats of truncated APC to beta-catenin degradation and selection of APC mutations in colorectal tumours from FAP patients.
    Kohler EM; Brauburger K; Behrens J; Schneikert J
    Oncogene; 2010 Mar; 29(11):1663-71. PubMed ID: 19966865
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel tissue-based ß-catenin gene and immunohistochemical analysis to exclude familial adenomatous polyposis among children with hepatoblastoma tumors.
    Dubbink HJ; Hollink IHIM; Avenca Valente C; Wang W; Liu P; Doukas M; van Noesel MM; Dinjens WNM; Wagner A; Smits R
    Pediatr Blood Cancer; 2018 Jun; 65(6):e26991. PubMed ID: 29446530
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing.
    Crespo M; Vilar E; Tsai SY; Chang K; Amin S; Srinivasan T; Zhang T; Pipalia NH; Chen HJ; Witherspoon M; Gordillo M; Xiang JZ; Maxfield FR; Lipkin S; Evans T; Chen S
    Nat Med; 2017 Jul; 23(7):878-884. PubMed ID: 28628110
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ubiquitylation and degradation of adenomatous polyposis coli by MKRN1 enhances Wnt/β-catenin signaling.
    Lee HK; Lee EW; Seo J; Jeong M; Lee SH; Kim SY; Jho EH; Choi CH; Chung JY; Song J
    Oncogene; 2018 Aug; 37(31):4273-4286. PubMed ID: 29713058
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation.
    Schneikert J; Vijaya Chandra SH; Ruppert JG; Ray S; Wenzel EM; Behrens J
    PLoS One; 2013; 8(7):e68072. PubMed ID: 23840886
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Beta-catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumours.
    Kohler EM; Chandra SH; Behrens J; Schneikert J
    Hum Mol Genet; 2009 Jan; 18(2):213-26. PubMed ID: 18854359
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Analysis of K-ras, APC, and beta-catenin in aberrant crypt foci in sporadic adenoma, cancer, and familial adenomatous polyposis.
    Takayama T; Ohi M; Hayashi T; Miyanishi K; Nobuoka A; Nakajima T; Satoh T; Takimoto R; Kato J; Sakamaki S; Niitsu Y
    Gastroenterology; 2001 Sep; 121(3):599-611. PubMed ID: 11522744
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oncogenic KRAS is not necessary for Wnt signalling activation in APC-associated FAP adenomas.
    Obrador-Hevia A; Chin SF; González S; Rees J; Vilardell F; Greenson JK; Cordero D; Moreno V; Caldas C; Capellá G
    J Pathol; 2010 May; 221(1):57-67. PubMed ID: 20196079
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Barrett's esophagus in the patients with familial adenomatous polyposis.
    Gatalica Z; Chen M; Snyder C; Mittal S; Lynch HT
    Fam Cancer; 2014 Jun; 13(2):213-7. PubMed ID: 23771323
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.