BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

339 related articles for article (PubMed ID: 31462709)

  • 1. TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment.
    Sirkisoon SR; Carpenter RL; Rimkus T; Doheny D; Zhu D; Aguayo NR; Xing F; Chan M; Ruiz J; Metheny-Barlow LJ; Strowd R; Lin J; Regua AT; Arrigo A; Anguelov M; Pasche B; Debinski W; Watabe K; Lo HW
    Oncogene; 2020 Jan; 39(1):64-78. PubMed ID: 31462709
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative breast cancers and HER2-enriched breast cancer.
    Sirkisoon SR; Carpenter RL; Rimkus T; Anderson A; Harrison A; Lange AM; Jin G; Watabe K; Lo HW
    Oncogene; 2018 May; 37(19):2502-2514. PubMed ID: 29449694
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Truncated Glioma-Associated Oncogene Homolog 1 (tGLI1) Mediates Mesenchymal Glioblastoma via Transcriptional Activation of CD44.
    Rimkus TK; Carpenter RL; Sirkisoon S; Zhu D; Pasche BC; Chan MD; Lesser GJ; Tatter SB; Watabe K; Debinski W; Lo HW
    Cancer Res; 2018 May; 78(10):2589-2600. PubMed ID: 29463580
    [TBL] [Abstract][Full Text] [Related]  

  • 4. An FDA-Approved Antifungal, Ketoconazole, and Its Novel Derivative Suppress tGLI1-Mediated Breast Cancer Brain Metastasis by Inhibiting the DNA-Binding Activity of Brain Metastasis-Promoting Transcription Factor tGLI1.
    Doheny D; Manore S; Sirkisoon SR; Zhu D; Aguayo NR; Harrison A; Najjar M; Anguelov M; Cox AO; Furdui CM; Watabe K; Hollis T; Thomas A; Strowd R; Lo HW
    Cancers (Basel); 2022 Aug; 14(17):. PubMed ID: 36077791
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells.
    Cao X; Geradts J; Dewhirst MW; Lo HW
    Oncogene; 2012 Jan; 31(1):104-15. PubMed ID: 21666711
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Estrogen promotes stemness and invasiveness of ER-positive breast cancer cells through Gli1 activation.
    Sun Y; Wang Y; Fan C; Gao P; Wang X; Wei G; Wei J
    Mol Cancer; 2014 Jun; 13():137. PubMed ID: 24889938
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Breast cancer extracellular vesicles-derived miR-1290 activates astrocytes in the brain metastatic microenvironment via the FOXA2→CNTF axis to promote progression of brain metastases.
    Sirkisoon SR; Wong GL; Aguayo NR; Doheny DL; Zhu D; Regua AT; Arrigo A; Manore SG; Wagner C; Thomas A; Singh R; Xing F; Jin G; Watabe K; Lo HW
    Cancer Lett; 2022 Aug; 540():215726. PubMed ID: 35589002
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The gain-of-function GLI1 transcription factor TGLI1 enhances expression of VEGF-C and TEM7 to promote glioblastoma angiogenesis.
    Carpenter RL; Paw I; Zhu H; Sirkisoon S; Xing F; Watabe K; Debinski W; Lo HW
    Oncotarget; 2015 Sep; 6(26):22653-65. PubMed ID: 26093087
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The embryonic type of SPP1 transcriptional regulation is re-activated in glioblastoma.
    Kijewska M; Kocyk M; Kloss M; Stepniak K; Korwek Z; Polakowska R; Dabrowski M; Gieryng A; Wojtas B; Ciechomska IA; Kaminska B
    Oncotarget; 2017 Mar; 8(10):16340-16355. PubMed ID: 28030801
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hyaluronan-CD44v3 interaction with Oct4-Sox2-Nanog promotes miR-302 expression leading to self-renewal, clonal formation, and cisplatin resistance in cancer stem cells from head and neck squamous cell carcinoma.
    Bourguignon LY; Wong G; Earle C; Chen L
    J Biol Chem; 2012 Sep; 287(39):32800-24. PubMed ID: 22847005
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis.
    Doheny D; Sirkisoon S; Carpenter RL; Aguayo NR; Regua AT; Anguelov M; Manore SG; Arrigo A; Jalboush SA; Wong GL; Yu Y; Wagner CJ; Chan M; Ruiz J; Thomas A; Strowd R; Lin J; Lo HW
    Oncogene; 2020 Oct; 39(42):6589-6605. PubMed ID: 32929154
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cell fate determination factor Dachshund reprograms breast cancer stem cell function.
    Wu K; Jiao X; Li Z; Katiyar S; Casimiro MC; Yang W; Zhang Q; Willmarth NE; Chepelev I; Crosariol M; Wei Z; Hu J; Zhao K; Pestell RG
    J Biol Chem; 2011 Jan; 286(3):2132-42. PubMed ID: 20937839
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cleaved CD44 intracellular domain supports activation of stemness factors and promotes tumorigenesis of breast cancer.
    Cho Y; Lee HW; Kang HG; Kim HY; Kim SJ; Chun KH
    Oncotarget; 2015 Apr; 6(11):8709-21. PubMed ID: 25909162
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparison of Cellular Transforming Activity of OCT4, NANOG, and SOX2 in Immortalized Astrocytes.
    Seo S; Jeon HY; Kim H
    DNA Cell Biol; 2017 Nov; 36(11):1000-1009. PubMed ID: 28933914
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gli1 expression in cancer stem-like cells predicts poor prognosis in patients with lung squamous cell carcinoma.
    Cui Y; Cui CA; Yang ZT; Ni WD; Jin Y; Xuan YH
    Exp Mol Pathol; 2017 Apr; 102(2):347-353. PubMed ID: 28286162
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A class of genes in the HER2 regulon that is poised for transcription in breast cancer cell lines and expressed in human breast tumors.
    Rahmatpanah FB; Jia Z; Chen X; Char JE; Men B; Franke AC; Jones FE; McClelland M; Mercola D
    Oncotarget; 2015 Jan; 6(2):1286-301. PubMed ID: 25428913
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [LincRNA-ROR functions as a ceRNA to regulate Oct4, Sox2, and Nanog expression by sponging miR-145 and its effect on biologic characteristics of colonic cancer stem cells].
    Yan ZY; Sun XC
    Zhonghua Bing Li Xue Za Zhi; 2018 Apr; 47(4):284-290. PubMed ID: 29690669
    [No Abstract]   [Full Text] [Related]  

  • 18. Intracellular Notch1 Signaling in Cancer-Associated Fibroblasts Dictates the Plasticity and Stemness of Melanoma Stem/Initiating Cells.
    Du Y; Shao H; Moller M; Prokupets R; Tse YT; Liu ZJ
    Stem Cells; 2019 Jul; 37(7):865-875. PubMed ID: 30941836
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting LA7 breast cancer stem cells of rat through repressing the genes of stemness-related transcription factors using three different biological fluids.
    Pourbagher R; Akhavan-Niaki H; Jorsaraei SGA; Fattahi S; Sabour D; Zabihi E; Abedian Z; Ghasemi M; Golpour M; Mostafazadeh A
    Gene; 2020 Apr; 734():144381. PubMed ID: 31978510
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of pancreatic cancer stem cell characteristics by α-Mangostin: Molecular mechanisms involving Sonic hedgehog and Nanog.
    Ma Y; Yu W; Shrivastava A; Srivastava RK; Shankar S
    J Cell Mol Med; 2019 Apr; 23(4):2719-2730. PubMed ID: 30712329
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.