124 related articles for article (PubMed ID: 31463908)
1. Analysis of Aggrecanase Activity Using Neoepitope Antibodies.
Santamaria S; Yamamoto K
Methods Mol Biol; 2020; 2043():125-136. PubMed ID: 31463908
[TBL] [Abstract][Full Text] [Related]
2. Neoepitope antibodies against MMP-cleaved and aggrecanase-cleaved aggrecan.
Fosang AJ; Last K; Stanton H; Golub SB; Little CB; Brown L; Jackson DC
Methods Mol Biol; 2010; 622():312-47. PubMed ID: 20135291
[TBL] [Abstract][Full Text] [Related]
3. Monoclonal antibodies that specifically recognize neoepitope sequences generated by 'aggrecanase' and matrix metalloproteinase cleavage of aggrecan: application to catabolism in situ and in vitro.
Hughes CE; Caterson B; Fosang AJ; Roughley PJ; Mort JS
Biochem J; 1995 Feb; 305 ( Pt 3)(Pt 3):799-804. PubMed ID: 7531436
[TBL] [Abstract][Full Text] [Related]
4. ADAMTS-5 deficiency does not block aggrecanolysis at preferred cleavage sites in the chondroitin sulfate-rich region of aggrecan.
East CJ; Stanton H; Golub SB; Rogerson FM; Fosang AJ
J Biol Chem; 2007 Mar; 282(12):8632-40. PubMed ID: 17255106
[TBL] [Abstract][Full Text] [Related]
5. Development and characterization of a novel ELISA based assay for the quantitation of sub-nanomolar levels of neoepitope exposed NITEGE-containing aggrecan fragments.
Carter QL; Dotzlaf J; Swearingen C; Brittain I; Chambers M; Duffin K; Mitchell P; Thirunavukkarasu K
J Immunol Methods; 2007 Dec; 328(1-2):162-8. PubMed ID: 17942111
[TBL] [Abstract][Full Text] [Related]
6. Release of hyaluronan and hyaladherins (aggrecan G1 domain and link proteins) from articular cartilage exposed to ADAMTS-4 (aggrecanase 1) or ADAMTS-5 (aggrecanase 2).
Chockalingam PS; Zeng W; Morris EA; Flannery CR
Arthritis Rheum; 2004 Sep; 50(9):2839-48. PubMed ID: 15457452
[TBL] [Abstract][Full Text] [Related]
7. Characterization of an ADAMTS-5-mediated cleavage site in aggrecan in OSM-stimulated bovine cartilage.
Durigova M; Soucy P; Fushimi K; Nagase H; Mort JS; Roughley PJ
Osteoarthritis Cartilage; 2008 Oct; 16(10):1245-52. PubMed ID: 18372197
[TBL] [Abstract][Full Text] [Related]
8. ADAMTS-1-knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo.
Little CB; Mittaz L; Belluoccio D; Rogerson FM; Campbell IK; Meeker CT; Bateman JF; Pritchard MA; Fosang AJ
Arthritis Rheum; 2005 May; 52(5):1461-72. PubMed ID: 15880348
[TBL] [Abstract][Full Text] [Related]
9. Aggrecanases and aggrecanase-generated fragments in the human intervertebral disc at early and advanced stages of disc degeneration.
Patel KP; Sandy JD; Akeda K; Miyamoto K; Chujo T; An HS; Masuda K
Spine (Phila Pa 1976); 2007 Nov; 32(23):2596-603. PubMed ID: 17978660
[TBL] [Abstract][Full Text] [Related]
10. Fibroblast growth factor 2 inhibits induction of aggrecanase activity in human articular cartilage.
Sawaji Y; Hynes J; Vincent T; Saklatvala J
Arthritis Rheum; 2008 Nov; 58(11):3498-509. PubMed ID: 18975307
[TBL] [Abstract][Full Text] [Related]
11. ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage.
Collins-Racie LA; Flannery CR; Zeng W; Corcoran C; Annis-Freeman B; Agostino MJ; Arai M; DiBlasio-Smith E; Dorner AJ; Georgiadis KE; Jin M; Tan XY; Morris EA; LaVallie ER
Matrix Biol; 2004 Jul; 23(4):219-30. PubMed ID: 15296936
[TBL] [Abstract][Full Text] [Related]
12. Aggrecanolysis and in vitro matrix degradation in the immature bovine meniscus: mechanisms and functional implications.
Wilson CG; Vanderploeg EJ; Zuo F; Sandy JD; Levenston ME
Arthritis Res Ther; 2009; 11(6):R173. PubMed ID: 19919704
[TBL] [Abstract][Full Text] [Related]
13. Evidence of a novel aggrecan-degrading activity in cartilage: Studies of mice deficient in both ADAMTS-4 and ADAMTS-5.
Rogerson FM; Stanton H; East CJ; Golub SB; Tutolo L; Farmer PJ; Fosang AJ
Arthritis Rheum; 2008 Jun; 58(6):1664-73. PubMed ID: 18512787
[TBL] [Abstract][Full Text] [Related]
14. Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints.
Lark MW; Bayne EK; Flanagan J; Harper CF; Hoerrner LA; Hutchinson NI; Singer II; Donatelli SA; Weidner JR; Williams HR; Mumford RA; Lohmander LS
J Clin Invest; 1997 Jul; 100(1):93-106. PubMed ID: 9202061
[TBL] [Abstract][Full Text] [Related]
15. Interleukin-1 Acts via the JNK-2 Signaling Pathway to Induce Aggrecan Degradation by Human Chondrocytes.
Ismail HM; Yamamoto K; Vincent TL; Nagase H; Troeberg L; Saklatvala J
Arthritis Rheumatol; 2015 Jul; 67(7):1826-36. PubMed ID: 25776267
[TBL] [Abstract][Full Text] [Related]
16. Aggrecan is degraded by matrix metalloproteinases in human arthritis. Evidence that matrix metalloproteinase and aggrecanase activities can be independent.
Fosang AJ; Last K; Maciewicz RA
J Clin Invest; 1996 Nov; 98(10):2292-9. PubMed ID: 8941646
[TBL] [Abstract][Full Text] [Related]
17. Regulation of aggrecanases from the ADAMTS family and aggrecan neoepitope formation during in vitro chondrogenesis of human mesenchymal stem cells.
Boeuf S; Graf F; Fischer J; Moradi B; Little CB; Richter W
Eur Cell Mater; 2012 May; 23():320-32. PubMed ID: 22562232
[TBL] [Abstract][Full Text] [Related]
18. Analysis of aggrecan in human knee cartilage and synovial fluid indicates that aggrecanase (ADAMTS) activity is responsible for the catabolic turnover and loss of whole aggrecan whereas other protease activity is required for C-terminal processing in vivo.
Sandy JD; Verscharen C
Biochem J; 2001 Sep; 358(Pt 3):615-26. PubMed ID: 11535123
[TBL] [Abstract][Full Text] [Related]
19. Intra-articular injection of tumor necrosis factor-alpha in the rat: an acute and reversible in vivo model of cartilage proteoglycan degradation.
Malfait AM; Tortorella M; Thompson J; Hills R; Meyer DM; Jaffee BD; Chinn K; Ghoreishi-Haack N; Markosyan S; Arner EC
Osteoarthritis Cartilage; 2009 May; 17(5):627-35. PubMed ID: 19026578
[TBL] [Abstract][Full Text] [Related]
20. Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments.
Struglics A; Larsson S; Pratta MA; Kumar S; Lark MW; Lohmander LS
Osteoarthritis Cartilage; 2006 Feb; 14(2):101-13. PubMed ID: 16188468
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
