These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

399 related articles for article (PubMed ID: 31473473)

  • 1. Dual VEGFR-2/PIM-1 kinase inhibition towards surmounting the resistance to antiangiogenic agents via hybrid pyridine and thienopyridine-based scaffolds: Design, synthesis and biological evaluation.
    Rizk OH; Teleb M; Abu-Serie MM; Shaaban OG
    Bioorg Chem; 2019 Nov; 92():103189. PubMed ID: 31473473
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Eco-friendly synthesis of novel cyanopyridine derivatives and their anticancer and PIM-1 kinase inhibitory activities.
    Abouzid KAM; Al-Ansary GH; El-Naggar AM
    Eur J Med Chem; 2017 Jul; 134():357-365. PubMed ID: 28431341
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis and docking study of pyridine and thieno[2,3-b] pyridine derivatives as anticancer PIM-1 kinase inhibitors.
    Abdelaziz ME; El-Miligy MMM; Fahmy SM; Mahran MA; Hazzaa AA
    Bioorg Chem; 2018 Oct; 80():674-692. PubMed ID: 30064079
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, anticancer effect and molecular modeling of new thiazolylpyrazolyl coumarin derivatives targeting VEGFR-2 kinase and inducing cell cycle arrest and apoptosis.
    Mohamed TK; Batran RZ; Elseginy SA; Ali MM; Mahmoud AE
    Bioorg Chem; 2019 Apr; 85():253-273. PubMed ID: 30641320
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of new thieno[2,3-b]pyridine derivatives as pim-1 inhibitors.
    Naguib BH; El-Nassan HB
    J Enzyme Inhib Med Chem; 2016 Dec; 31(6):1718-25. PubMed ID: 27541740
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of novel pyrazolo[3,4-b]pyridine scaffold-based derivatives as potential PIM-1 kinase inhibitors in breast cancer MCF-7 cells.
    Nafie MS; Amer AM; Mohamed AK; Tantawy ES
    Bioorg Med Chem; 2020 Dec; 28(24):115828. PubMed ID: 33166925
    [TBL] [Abstract][Full Text] [Related]  

  • 7. New cyanopyridine-based scaffold as PIM-1 inhibitors and apoptotic inducers: Synthesis and SARs study.
    Farrag AM; Ibrahim MH; Mehany ABM; Ismail MMF
    Bioorg Chem; 2020 Dec; 105():104378. PubMed ID: 33099167
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, Synthesis, In Vitro Anti-cancer Activity, ADMET Profile and Molecular Docking of Novel Triazolo[3,4-a]phthalazine Derivatives Targeting VEGFR-2 Enzyme.
    El-Helby AA; Sakr H; Ayyad RRA; El-Adl K; Ali MM; Khedr F
    Anticancer Agents Med Chem; 2018; 18(8):1184-1196. PubMed ID: 29651967
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New Approaches for the Uses of Cyclohexan-1,4-dione for the Synthesis of 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-b]pyridine Derivatives used as Potential Anti-prostate Cancer Agents and Pim-1 Kinase Inhibitors.
    Mohareb RM; Abdo NYM; El-Sharkawy KA
    Anticancer Agents Med Chem; 2018; 18(12):1736-1749. PubMed ID: 29866019
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and cytotoxic evaluation of new thieno[2,3-d]pyrimidine analogues as VEGFR-2/AKT dual inhibitors, apoptosis and autophagy inducers.
    Abd El-Mawgoud HK; AboulMagd AM; Nemr MTM; Hemdan MM; Hassaballah AI; Farag PS
    Bioorg Chem; 2024 Sep; 150():107622. PubMed ID: 38996545
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective VEGFR-2 inhibitors: Synthesis of pyridine derivatives, cytotoxicity and apoptosis induction profiling.
    AbdelHaleem A; Mansour AO; AbdelKader M; Arafa RK
    Bioorg Chem; 2020 Oct; 103():104222. PubMed ID: 32889383
    [TBL] [Abstract][Full Text] [Related]  

  • 12. New bis([1,2,4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers: Design, synthesis, in silico studies, and anticancer evaluation.
    Alanazi MM; Mahdy HA; Alsaif NA; Obaidullah AJ; Alkahtani HM; Al-Mehizia AA; Alsubaie SM; Dahab MA; Eissa IH
    Bioorg Chem; 2021 Jul; 112():104949. PubMed ID: 34023640
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Utilization of cyanopyridine in design and synthesis of first-in-class anticancer dual acting PIM-1 kinase/HDAC inhibitors.
    Bass AKA; Nageeb EM; El-Zoghbi MS; Mohamed MFA; Badr M; Abuo-Rahma GEA
    Bioorg Chem; 2022 Feb; 119():105564. PubMed ID: 34959179
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of new quinoxaline-2(1H)-one-based anticancer agents targeting VEGFR-2 as inhibitors: Design, synthesis, and anti-proliferative evaluation.
    El-Adl K; Sakr HM; Yousef RG; Mehany ABM; Metwaly AM; Elhendawy MA; Radwan MM; ElSohly MA; Abulkhair HS; Eissa IH
    Bioorg Chem; 2021 Sep; 114():105105. PubMed ID: 34175720
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hypoxia-Inducible PIM Kinase Expression Promotes Resistance to Antiangiogenic Agents.
    Casillas AL; Toth RK; Sainz AG; Singh N; Desai AA; Kraft AS; Warfel NA
    Clin Cancer Res; 2018 Jan; 24(1):169-180. PubMed ID: 29084916
    [No Abstract]   [Full Text] [Related]  

  • 16. Synthesis and Biological Evaluation of Novel 4,5,6,7-Tetrahydrobenzo[D]-Thiazol-2- Yl Derivatives Derived from Dimedone with Anti-Tumor, C-Met, Tyrosine Kinase and Pim-1 Inhibitions.
    Mohareb RM; Abouzied AS; Abbas NS
    Anticancer Agents Med Chem; 2019; 19(12):1438-1453. PubMed ID: 31038076
    [TBL] [Abstract][Full Text] [Related]  

  • 17. EGFR/VEGFR-2 dual inhibitor and apoptotic inducer: Design, synthesis, anticancer activity and docking study of new 2-thioxoimidazolidin-4one derivatives.
    Mourad AAE; Farouk NA; El-Sayed EH; Mahdy ARE
    Life Sci; 2021 Jul; 277():119531. PubMed ID: 33887348
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, green synthesis, molecular docking and anticancer evaluations of diazepam bearing sulfonamide moieties as VEGFR-2 inhibitors.
    Saleh NM; El-Gaby MSA; El-Adl K; Abd El-Sattar NEA
    Bioorg Chem; 2020 Nov; 104():104350. PubMed ID: 33142416
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design and synthesis of novel Thiazolo[5,4-b]pyridine derivatives as potent and selective EGFR-TK inhibitors targeting resistance Mutations in non-small cell lung cancer.
    Borude AS; Deshmukh SR; Tiwari SV; Kumar SH; Thopate SR
    Eur J Med Chem; 2024 Oct; 276():116727. PubMed ID: 39094428
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New potent and selective inhibitor of Pim-1/3 protein kinases sensitizes human colon carcinoma cells to doxorubicin.
    Moreau P; Dezhenkova LG; Anizon F; Nauton L; Thery V; Liang S; Kaluzhny DN; Shtil AA
    Anticancer Agents Med Chem; 2014; 14(9):1228-36. PubMed ID: 25175798
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.