460 related articles for article (PubMed ID: 31477924)
1. Deep learning enables rapid identification of potent DDR1 kinase inhibitors.
Zhavoronkov A; Ivanenkov YA; Aliper A; Veselov MS; Aladinskiy VA; Aladinskaya AV; Terentiev VA; Polykovskiy DA; Kuznetsov MD; Asadulaev A; Volkov Y; Zholus A; Shayakhmetov RR; Zhebrak A; Minaeva LI; Zagribelnyy BA; Lee LH; Soll R; Madge D; Xing L; Guo T; Aspuru-Guzik A
Nat Biotechnol; 2019 Sep; 37(9):1038-1040. PubMed ID: 31477924
[TBL] [Abstract][Full Text] [Related]
2. Design and Synthesis of DDR1 Inhibitors with a Desired Pharmacophore Using Deep Generative Models.
Yoshimori A; Asawa Y; Kawasaki E; Tasaka T; Matsuda S; Sekikawa T; Tanabe S; Neya M; Natsugari H; Kanai C
ChemMedChem; 2021 Mar; 16(6):955-958. PubMed ID: 33289306
[TBL] [Abstract][Full Text] [Related]
3. Discovery of Pyrazolo[3,4-
Tan X; Li C; Yang R; Zhao S; Li F; Li X; Chen L; Wan X; Liu X; Yang T; Tong X; Xu T; Cui R; Jiang H; Zhang S; Liu H; Zheng M
J Med Chem; 2022 Jan; 65(1):103-119. PubMed ID: 34821145
[TBL] [Abstract][Full Text] [Related]
4. Structure-Based Design of Tetrahydroisoquinoline-7-carboxamides as Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors.
Wang Z; Bian H; Bartual SG; Du W; Luo J; Zhao H; Zhang S; Mo C; Zhou Y; Xu Y; Tu Z; Ren X; Lu X; Brekken RA; Yao L; Bullock AN; Su J; Ding K
J Med Chem; 2016 Jun; 59(12):5911-6. PubMed ID: 27219676
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and biological evaluation of novel dasatinib analogues as potent DDR1 and DDR2 kinase inhibitors.
Liu L; Hussain M; Luo J; Duan A; Chen C; Tu Z; Zhang J
Chem Biol Drug Des; 2017 Mar; 89(3):420-427. PubMed ID: 27589335
[TBL] [Abstract][Full Text] [Related]
6. Discovery of 4-amino-1H-pyrazolo[3,4-d]pyrimidin derivatives as novel discoidin domain receptor 1 (DDR1) inhibitors.
Dong R; Zhou X; Wang M; Li W; Zhang JY; Zheng X; Tang KX; Sun LP
Bioorg Med Chem; 2021 Jan; 29():115876. PubMed ID: 33246255
[TBL] [Abstract][Full Text] [Related]
7. A patent review of discoidin domain receptor 1 (DDR1) modulators (2014-present).
Guo J; Zhang Z; Ding K
Expert Opin Ther Pat; 2020 May; 30(5):341-350. PubMed ID: 32077340
[No Abstract] [Full Text] [Related]
8. Identification of novel inhibitors of DDR1 against idiopathic pulmonary fibrosis by integrative transcriptome meta-analysis, computational and experimental screening.
Chen C; Deng J; Yu X; Wu F; Men K; Yang Q; Zhu Y; Liu X; Jiang Q
Mol Biosyst; 2016 Apr; 12(5):1540-51. PubMed ID: 26956955
[TBL] [Abstract][Full Text] [Related]
9. The Journey of DDR1 and DDR2 Kinase Inhibitors as Rising Stars in the Fight Against Cancer.
Elkamhawy A; Lu Q; Nada H; Woo J; Quan G; Lee K
Int J Mol Sci; 2021 Jun; 22(12):. PubMed ID: 34207360
[TBL] [Abstract][Full Text] [Related]
10. DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome.
Richter H; Satz AL; Bedoucha M; Buettelmann B; Petersen AC; Harmeier A; Hermosilla R; Hochstrasser R; Burger D; Gsell B; Gasser R; Huber S; Hug MN; Kocer B; Kuhn B; Ritter M; Rudolph MG; Weibel F; Molina-David J; Kim JJ; Santos JV; Stihle M; Georges GJ; Bonfil RD; Fridman R; Uhles S; Moll S; Faul C; Fornoni A; Prunotto M
ACS Chem Biol; 2019 Jan; 14(1):37-49. PubMed ID: 30452219
[TBL] [Abstract][Full Text] [Related]
11. Two-step release of kinase autoinhibition in discoidin domain receptor 1.
Sammon D; Hohenester E; Leitinger B
Proc Natl Acad Sci U S A; 2020 Sep; 117(36):22051-22060. PubMed ID: 32839343
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of EP300 and DDR1 synergistically alleviates pulmonary fibrosis in vitro and in vivo.
Tao J; Zhang M; Wen Z; Wang B; Zhang L; Ou Y; Tang X; Yu X; Jiang Q
Biomed Pharmacother; 2018 Oct; 106():1727-1733. PubMed ID: 30119248
[TBL] [Abstract][Full Text] [Related]
13. Discoidin domain receptor 1-deletion ameliorates fibrosis and promotes adipose tissue beiging, brown fat activity, and increased metabolic rate in a mouse model of cardiometabolic disease.
Lino M; Ngai D; Liu A; Mohabeer A; Harper C; Caruso LL; Schroer SA; Fu F; McKee T; Giacca A; Woo M; Bendeck MP
Mol Metab; 2020 Sep; 39():101006. PubMed ID: 32360427
[TBL] [Abstract][Full Text] [Related]
14. 2-Amino-2,3-dihydro-1
Zhu D; Huang H; Pinkas DM; Luo J; Ganguly D; Fox AE; Arner E; Xiang Q; Tu ZC; Bullock AN; Brekken RA; Ding K; Lu X
J Med Chem; 2019 Aug; 62(16):7431-7444. PubMed ID: 31310125
[TBL] [Abstract][Full Text] [Related]
15. Development of a Selective Dual Discoidin Domain Receptor (DDR)/p38 Kinase Chemical Probe.
Röhm S; Berger BT; Schröder M; Chatterjee D; Mathea S; Joerger AC; Pinkas DM; Bufton JC; Tjaden A; Kovooru L; Kudolo M; Pohl C; Bullock AN; Müller S; Laufer S; Knapp S
J Med Chem; 2021 Sep; 64(18):13451-13474. PubMed ID: 34506142
[TBL] [Abstract][Full Text] [Related]
16. What Makes a Kinase Promiscuous for Inhibitors?
Hanson SM; Georghiou G; Thakur MK; Miller WT; Rest JS; Chodera JD; Seeliger MA
Cell Chem Biol; 2019 Mar; 26(3):390-399.e5. PubMed ID: 30612951
[TBL] [Abstract][Full Text] [Related]
17. Has Drug Design Augmented by Artificial Intelligence Become a Reality?
Chen H; Engkvist O
Trends Pharmacol Sci; 2019 Nov; 40(11):806-809. PubMed ID: 31629547
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of DDR1 enhances in vivo chemosensitivity in KRAS-mutant lung adenocarcinoma.
Nokin MJ; Darbo E; Travert C; Drogat B; Lacouture A; San José S; Cabrera N; Turcq B; Prouzet-Mauleon V; Falcone M; Villanueva A; Wang H; Herfs M; Mosteiro M; Jänne PA; Pujol JL; Maraver A; Barbacid M; Nadal E; Santamaría D; Ambrogio C
JCI Insight; 2020 Aug; 5(15):. PubMed ID: 32759499
[TBL] [Abstract][Full Text] [Related]
19. Selective pharmacological inhibition of DDR1 prevents experimentally-induced glomerulonephritis in prevention and therapeutic regime.
Moll S; Yasui Y; Abed A; Murata T; Shimada H; Maeda A; Fukushima N; Kanamori M; Uhles S; Badi L; Cagarelli T; Formentini I; Drawnel F; Georges G; Bergauer T; Gasser R; Bonfil RD; Fridman R; Richter H; Funk J; Moeller MJ; Chatziantoniou C; Prunotto M
J Transl Med; 2018 Jun; 16(1):148. PubMed ID: 29859097
[TBL] [Abstract][Full Text] [Related]
20. Targeting of DDR1 with antibody-drug conjugates has antitumor effects in a mouse model of colon carcinoma.
Tao Y; Wang R; Lai Q; Wu M; Wang Y; Jiang X; Zeng L; Zhou S; Li Z; Yang T; Yao Y; Wu Y; Yu L; Fu Y; Lai W; Peng Y; Lu Y; Zhang Z; Guo C; Zhang G; Gou L; Yang J
Mol Oncol; 2019 Sep; 13(9):1855-1873. PubMed ID: 31116512
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
