BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 31480625)

  • 1. Structure-Based Pharmacophore Design and Virtual Screening for Novel Tubulin Inhibitors with Potential Anticancer Activity.
    Zhou Y; Di B; Niu MM
    Molecules; 2019 Sep; 24(17):. PubMed ID: 31480625
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tubulin inhibitors: pharmacophore modeling, virtual screening and molecular docking.
    Niu MM; Qin JY; Tian CP; Yan XF; Dong FG; Cheng ZQ; Fida G; Yang M; Chen HY; Gu YQ
    Acta Pharmacol Sin; 2014 Jul; 35(7):967-79. PubMed ID: 24909516
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH; Dahab MA; Ibrahim MK; Alsaif NA; Alanazi AZ; Eissa SI; Mehany ABM; Beauchemin AM
    Bioorg Chem; 2021 Jul; 112():104965. PubMed ID: 34020238
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of Essential 2D and 3D Chemical Features for Discovery of the Novel Tubulin Polymerization Inhibitors.
    Azimi F; Ghasemi JB; Saghaei L; Hassanzadeh F; Mahdavi M; Sadeghi-Aliabadi H; Scotti MT; Scotti L
    Curr Top Med Chem; 2019; 19(13):1092-1120. PubMed ID: 31109275
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Combined Molecular Docking, 3D-QSAR, and Pharmacophore Model: Design of Novel Tubulin Polymerization Inhibitors by Binding to Colchicine-binding Site.
    Li DD; Qin YJ; Zhang X; Yin Y; Zhu HL; Zhao LG
    Chem Biol Drug Des; 2015 Oct; 86(4):731-45. PubMed ID: 25711282
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and evaluation of novel bis-substituted aromatic amide dithiocarbamate derivatives as colchicine site tubulin polymerization inhibitors with potent anticancer activities.
    Sun YX; Song J; Kong LJ; Sha BB; Tian XY; Liu XJ; Hu T; Chen P; Zhang SY
    Eur J Med Chem; 2022 Feb; 229():114069. PubMed ID: 34971875
    [TBL] [Abstract][Full Text] [Related]  

  • 7.
    Hadizadeh F; Ghodsi R; Mirzaei S; Sahebkar A
    Comput Math Methods Med; 2022; 2022():4004068. PubMed ID: 35075369
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, Synthesis and Evaluation of 2,4-Diaminoquinazoline Derivatives as Potential Tubulin Polymerization Inhibitors.
    Herrera-Vázquez FS; Matadamas-Martínez F; Aguayo-Ortiz R; Dominguez L; Ramírez-Apan T; Yépez-Mulia L; Hernández-Luis F
    ChemMedChem; 2020 Oct; 15(19):1802-1812. PubMed ID: 32686342
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site.
    Liu YN; Wang JJ; Ji YT; Zhao GD; Tang LQ; Zhang CM; Guo XL; Liu ZP
    J Med Chem; 2016 Jun; 59(11):5341-55. PubMed ID: 27172319
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Design, Synthesis, and Biological Activities of Pyrrole-Based Carboxamides: The Novel Tubulin Inhibitors Targeting the Colchicine-Binding Site.
    Boichuk S; Galembikova A; Syuzov K; Dunaev P; Bikinieva F; Aukhadieva A; Zykova S; Igidov N; Gankova K; Novikova M; Kopnin P
    Molecules; 2021 Sep; 26(19):. PubMed ID: 34641324
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity.
    Chiang YK; Kuo CC; Wu YS; Chen CT; Coumar MS; Wu JS; Hsieh HP; Chang CY; Jseng HY; Wu MH; Leou JS; Song JS; Chang JY; Lyu PC; Chao YS; Wu SY
    J Med Chem; 2009 Jul; 52(14):4221-33. PubMed ID: 19507860
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of Novel β-Tubulin Inhibitors Using a Combined
    Horgan MJ; Zell L; Siewert B; Stuppner H; Schuster D; Temml V
    J Chem Inf Model; 2023 Oct; 63(20):6396-6411. PubMed ID: 37774242
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of novel tubulin inhibitors targeting the colchicine binding site via virtual screening, structural optimization and antitumor evaluation.
    Liu W; Jia H; Guan M; Cui M; Lan Z; He Y; Guo Z; Jiang R; Dong G; Wang S
    Bioorg Chem; 2022 Jan; 118():105486. PubMed ID: 34801948
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
    Lai Q; Wang Y; Wang R; Lai W; Tang L; Tao Y; Liu Y; Zhang R; Huang L; Xiang H; Zeng S; Gou L; Chen H; Yao Y; Yang J
    Eur J Med Chem; 2018 Aug; 156():162-179. PubMed ID: 30006162
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of novel tubulin inhibitors targeting taxanes site by virtual screening, molecular dynamic simulation, and biological evaluation.
    Zhang H; Mao J; Yang YL; Liu CT; Shen C; Zhang HR; Xie HZ; Ding L
    J Cell Biochem; 2021 Nov; 122(11):1609-1624. PubMed ID: 34237164
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and biological evaluation of novel imidazole-chalcone derivatives as potential anticancer agents and tubulin polymerization inhibitors.
    Rahimzadeh Oskuei S; Mirzaei S; Reza Jafari-Nik M; Hadizadeh F; Eisvand F; Mosaffa F; Ghodsi R
    Bioorg Chem; 2021 Jul; 112():104904. PubMed ID: 33933802
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ligand- and structural-based discovery of potential small molecules that target the colchicine site of tubulin for cancer treatment.
    Guo Q; Zhang H; Deng Y; Zhai S; Jiang Z; Zhu D; Wang L
    Eur J Med Chem; 2020 Jun; 196():112328. PubMed ID: 32320841
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hybrid Pharmacophore Design, Molecular Docking, Synthesis, and Biological Evaluation of Novel Aldimine-Type Schiff Base Derivatives as Tubulin Polymerization Inhibitor.
    Ameri A; Khodarahmi G; Forootanfar H; Hassanzadeh F; Hakimelahi GH
    Chem Biodivers; 2018 Mar; 15(3):e1700518. PubMed ID: 29292595
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of novel αβ-tubulin modulators with antiproliferative activity directed to cancer therapy using ligand and structure-based virtual screening.
    Federico LB; Silva GM; de Fraga Dias A; Figueiró F; Battastini AMO; Dos Santos CBR; Costa LT; Rosa JMC; de Paula da Silva CHT
    Int J Biol Macromol; 2020 Dec; 165(Pt B):3040-3050. PubMed ID: 33736292
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design and synthesis of (2-(phenylamino)thieno[3,2-d]pyrimidin-4-yl)(3,4,5-trimethoxyphenyl)methanone analogues as potent anti-tubulin polymerization agents.
    Tian C; Chen X; Zhang Z; Wang X; Liu J
    Eur J Med Chem; 2019 Dec; 183():111679. PubMed ID: 31541870
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.