BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

211 related articles for article (PubMed ID: 31481236)

  • 1. The C-terminal HCN4 variant P883R alters channel properties and acts as genetic modifier of atrial fibrillation and structural heart disease.
    Weigl I; Geschwill P; Reiss M; Bruehl C; Draguhn A; Koenen M; Sedaghat-Hamedani F; Meder B; Thomas D; Katus HA; Schweizer PA
    Biochem Biophys Res Commun; 2019 Oct; 519(1):141-147. PubMed ID: 31481236
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Altered HCN4 channel C-linker interaction is associated with familial tachycardia-bradycardia syndrome and atrial fibrillation.
    Duhme N; Schweizer PA; Thomas D; Becker R; Schröter J; Barends TR; Schlichting I; Draguhn A; Bruehl C; Katus HA; Koenen M
    Eur Heart J; 2013 Sep; 34(35):2768-75. PubMed ID: 23178648
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The symptom complex of familial sinus node dysfunction and myocardial noncompaction is associated with mutations in the HCN4 channel.
    Schweizer PA; Schröter J; Greiner S; Haas J; Yampolsky P; Mereles D; Buss SJ; Seyler C; Bruehl C; Draguhn A; Koenen M; Meder B; Katus HA; Thomas D
    J Am Coll Cardiol; 2014 Aug; 64(8):757-67. PubMed ID: 25145518
    [TBL] [Abstract][Full Text] [Related]  

  • 4.
    Nakano Y; Ochi H; Sairaku A; Onohara Y; Tokuyama T; Motoda C; Matsumura H; Tomomori S; Amioka M; Hironobe N; Ohkubo Y; Okamura S; Makita N; Yoshida Y; Chayama K; Kihara Y
    Circ Genom Precis Med; 2018 Jul; 11(7):e001980. PubMed ID: 29987112
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel trafficking-defective HCN4 mutation is associated with early-onset atrial fibrillation.
    Macri V; Mahida SN; Zhang ML; Sinner MF; Dolmatova EV; Tucker NR; McLellan M; Shea MA; Milan DJ; Lunetta KL; Benjamin EJ; Ellinor PT
    Heart Rhythm; 2014 Jun; 11(6):1055-1062. PubMed ID: 24607718
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In Vitro Analyses of Novel HCN4 Gene Mutations.
    Möller M; Silbernagel N; Wrobel E; Stallmayer B; Amedonu E; Rinné S; Peischard S; Meuth SG; Wünsch B; Strutz-Seebohm N; Decher N; Schulze-Bahr E; Seebohm G
    Cell Physiol Biochem; 2018; 49(3):1197-1207. PubMed ID: 30196304
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Correlation between
    Li XH; Hu YM; Yin GL; Wu P
    Artif Cells Nanomed Biotechnol; 2019 Dec; 47(1):2989-2993. PubMed ID: 31315459
    [No Abstract]   [Full Text] [Related]  

  • 8. The HCN4 channel mutation D553N associated with bradycardia has a C-linker mediated gating defect.
    Netter MF; Zuzarte M; Schlichthörl G; Klöcker N; Decher N
    Cell Physiol Biochem; 2012; 30(5):1227-40. PubMed ID: 23075627
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Disease-associated HCN4 V759I variant is not sufficient to impair cardiac pacemaking.
    Erlenhardt N; Kletke O; Wohlfarth F; Komadowski MA; Clasen L; Makimoto H; Rinné S; Kelm M; Jungen C; Decher N; Meyer C; Klöcker N
    Pflugers Arch; 2020 Dec; 472(12):1733-1742. PubMed ID: 33095298
    [TBL] [Abstract][Full Text] [Related]  

  • 10. HCN4 mutations in multiple families with bradycardia and left ventricular noncompaction cardiomyopathy.
    Milano A; Vermeer AM; Lodder EM; Barc J; Verkerk AO; Postma AV; van der Bilt IA; Baars MJ; van Haelst PL; Caliskan K; Hoedemaekers YM; Le Scouarnec S; Redon R; Pinto YM; Christiaans I; Wilde AA; Bezzina CR
    J Am Coll Cardiol; 2014 Aug; 64(8):745-56. PubMed ID: 25145517
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Point mutation in the HCN4 cardiac ion channel pore affecting synthesis, trafficking, and functional expression is associated with familial asymptomatic sinus bradycardia.
    Nof E; Luria D; Brass D; Marek D; Lahat H; Reznik-Wolf H; Pras E; Dascal N; Eldar M; Glikson M
    Circulation; 2007 Jul; 116(5):463-70. PubMed ID: 17646576
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pacemaker channel dysfunction in a patient with sinus node disease.
    Schulze-Bahr E; Neu A; Friederich P; Kaupp UB; Breithardt G; Pongs O; Isbrandt D
    J Clin Invest; 2003 May; 111(10):1537-45. PubMed ID: 12750403
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutation in S6 domain of HCN4 channel in patient with suspected Brugada syndrome modifies channel function.
    Biel S; Aquila M; Hertel B; Berthold A; Neumann T; DiFrancesco D; Moroni A; Thiel G; Kauferstein S
    Pflugers Arch; 2016 Oct; 468(10):1663-71. PubMed ID: 27553229
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functional reclassification of variants of uncertain significance in the HCN4 gene identified in sudden unexpected death.
    Dong J; Subbotina E; Williams N; Sampson BA; Tang Y; Coetzee WA
    Pacing Clin Electrophysiol; 2019 Feb; 42(2):275-282. PubMed ID: 30578647
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sick sinus syndrome with HCN4 mutations shows early onset and frequent association with atrial fibrillation and left ventricular noncompaction.
    Ishikawa T; Ohno S; Murakami T; Yoshida K; Mishima H; Fukuoka T; Kimoto H; Sakamoto R; Ohkusa T; Aiba T; Nogami A; Sumitomo N; Shimizu W; Yoshiura KI; Horigome H; Horie M; Makita N
    Heart Rhythm; 2017 May; 14(5):717-724. PubMed ID: 28104484
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of Functional Variant Enhancers Associated With Atrial Fibrillation.
    van Ouwerkerk AF; Bosada FM; Liu J; Zhang J; van Duijvenboden K; Chaffin M; Tucker NR; Pijnappels D; Ellinor PT; Barnett P; de Vries AAF; Christoffels VM
    Circ Res; 2020 Jul; 127(2):229-243. PubMed ID: 32248749
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A mutant HCN4 channel in a family with bradycardia, left bundle branch block, and left ventricular noncompaction.
    Yokoyama R; Kinoshita K; Hata Y; Abe M; Matsuoka K; Hirono K; Kano M; Nakazawa M; Ichida F; Nishida N; Tabata T
    Heart Vessels; 2018 Jul; 33(7):802-819. PubMed ID: 29349559
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A gain-of-function HCN4 mutant in the HCN domain is responsible for inappropriate sinus tachycardia in a Spanish family.
    Cámara-Checa A; Perin F; Rubio-Alarcón M; Dago M; Crespo-García T; Rapún J; Marín M; Cebrián J; Gómez R; Bermúdez-Jiménez F; Monserrat L; Tamargo J; Caballero R; Jiménez-Jáimez J; Delpón E
    Proc Natl Acad Sci U S A; 2023 Dec; 120(49):e2305135120. PubMed ID: 38032931
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Relationship between two arrhythmias: sinus node dysfunction and atrial fibrillation.
    Zhao J; Liu T; Li G
    Arch Med Res; 2014 May; 45(4):351-5. PubMed ID: 24825742
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Altered expression of hyperpolarization-activated cyclic nucleotide-gated channels and microRNA-1 and -133 in patients with age-associated atrial fibrillation.
    Li YD; Hong YF; Yusufuaji Y; Tang BP; Zhou XH; Xu GJ; Li JX; Sun L; Zhang JH; Xin Q; Xiong J; Ji YT; Zhang Y
    Mol Med Rep; 2015 Sep; 12(3):3243-3248. PubMed ID: 26005035
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.