These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 31484924)

  • 1. Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions.
    Akula MK; Ibrahim MX; Ivarsson EG; Khan OM; Kumar IT; Erlandsson M; Karlsson C; Xu X; Brisslert M; Brakebusch C; Wang D; Bokarewa M; Sayin VI; Bergo MO
    Nat Commun; 2019 Sep; 10(1):3975. PubMed ID: 31484924
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Geranylgeranyltransferase type I (GGTase-I) deficiency hyperactivates macrophages and induces erosive arthritis in mice.
    Khan OM; Ibrahim MX; Jonsson IM; Karlsson C; Liu M; Sjogren AK; Olofsson FJ; Brisslert M; Andersson S; Ohlsson C; Hultén LM; Bokarewa M; Bergo MO
    J Clin Invest; 2011 Feb; 121(2):628-39. PubMed ID: 21266780
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Geranylgeranyltransferase I promotes human glioma cell growth through Rac1 membrane association and activation.
    Zhou X; Qian J; Hua L; Shi Q; Liu Z; Xu Y; Sang B; Mo J; Yu R
    J Mol Neurosci; 2013 Jan; 49(1):130-9. PubMed ID: 23073905
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibiting PGGT1B Disrupts Function of RHOA, Resulting in T-cell Expression of Integrin α4β7 and Development of Colitis in Mice.
    López-Posadas R; Fastancz P; Martínez-Sánchez LDC; Panteleev-Ivlev J; Thonn V; Kisseleva T; Becker LS; Schulz-Kuhnt A; Zundler S; Wirtz S; Atreya R; Carlé B; Friedrich O; Schürmann S; Waldner MJ; Neufert C; Brakebusch CH; Bergö MO; Neurath MF; Atreya I
    Gastroenterology; 2019 Nov; 157(5):1293-1309. PubMed ID: 31302143
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice.
    Khan OM; Akula MK; Skålen K; Karlsson C; Ståhlman M; Young SG; Borén J; Bergo MO
    Circulation; 2013 Feb; 127(7):782-90. PubMed ID: 23334894
    [TBL] [Abstract][Full Text] [Related]  

  • 6. IQGAP1 Interaction with RHO Family Proteins Revisited: KINETIC AND EQUILIBRIUM EVIDENCE FOR MULTIPLE DISTINCT BINDING SITES.
    Nouri K; Fansa EK; Amin E; Dvorsky R; Gremer L; Willbold D; Schmitt L; Timson DJ; Ahmadian MR
    J Biol Chem; 2016 Dec; 291(51):26364-26376. PubMed ID: 27815503
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Impaired geranylgeranyltransferase-I regulation reduces membrane-associated Rho protein levels in aged mouse brain.
    Afshordel S; Wood WG; Igbavboa U; Muller WE; Eckert GP
    J Neurochem; 2014 May; 129(4):732-42. PubMed ID: 24428713
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Control of antiviral innate immune response by protein geranylgeranylation.
    Yang S; Harding AT; Sweeney C; Miao D; Swan G; Zhou C; Jiang Z; Fitzgerald KA; Hammer G; Bergo MO; Kroh HK; Lacy DB; Sun C; Glogauer M; Que LG; Heaton NS; Wang D
    Sci Adv; 2019 May; 5(5):eaav7999. PubMed ID: 31149635
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases.
    Zhu Y; Casey PJ; Kumar AP; Pervaiz S
    Cell Death Dis; 2013 Apr; 4(4):e568. PubMed ID: 23559002
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The IQGAP1-Rac1 and IQGAP1-Cdc42 interactions: interfaces differ between the complexes.
    Owen D; Campbell LJ; Littlefield K; Evetts KA; Li Z; Sacks DB; Lowe PN; Mott HR
    J Biol Chem; 2008 Jan; 283(3):1692-1704. PubMed ID: 17984089
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ubiquitination of the scaffold protein IQGAP1 diminishes its interaction with and activation of the Rho GTPase CDC42.
    Gorisse L; Li Z; Wagner CD; Worthylake DK; Zappacosta F; Hedman AC; Annan RS; Sacks DB
    J Biol Chem; 2020 Apr; 295(15):4822-4835. PubMed ID: 32094223
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The perplexing case of the geranylgeranyl transferase-deficient mouse.
    Philips MR
    J Clin Invest; 2011 Feb; 121(2):510-3. PubMed ID: 21266773
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RhoGDI facilitates geranylgeranyltransferase-I-mediated RhoA prenylation.
    Tnimov Z; Abankwa D; Alexandrov K
    Biochem Biophys Res Commun; 2014 Oct; 452(4):967-73. PubMed ID: 25223799
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rho isoform-specific interaction with IQGAP1 promotes breast cancer cell proliferation and migration.
    Casteel DE; Turner S; Schwappacher R; Rangaswami H; Su-Yuo J; Zhuang S; Boss GR; Pilz RB
    J Biol Chem; 2012 Nov; 287(45):38367-78. PubMed ID: 22992742
    [TBL] [Abstract][Full Text] [Related]  

  • 15. IQGAP1 activates Tcf signal independent of Rac1 and Cdc42 in injury and repair of bronchial epithelial cells.
    Wang Y; Wang A; Wang F; Wang M; Zhu M; Ma Y; Wu R
    Exp Mol Pathol; 2008 Oct; 85(2):122-8. PubMed ID: 18625219
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.
    Zhang J; Guo J; Dzhagalov I; He YW
    Nat Immunol; 2005 Sep; 6(9):911-9. PubMed ID: 16041389
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Different roles of the small GTPases Rac1, Cdc42, and RhoG in CALEB/NGC-induced dendritic tree complexity.
    Schulz J; Franke K; Frick M; Schumacher S
    J Neurochem; 2016 Oct; 139(1):26-39. PubMed ID: 27412363
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SmgGDS-607 Regulation of RhoA GTPase Prenylation Is Nucleotide-Dependent.
    Jennings BC; Lawton AJ; Rizk Z; Fierke CA
    Biochemistry; 2018 Jul; 57(29):4289-4298. PubMed ID: 29940100
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New model for the interaction of IQGAP1 with CDC42 and RAC1.
    Nouri K; Timson DJ; Ahmadian MR
    Small GTPases; 2020 Jan; 11(1):16-22. PubMed ID: 28622072
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rho-A prenylation and signaling link epithelial homeostasis to intestinal inflammation.
    López-Posadas R; Becker C; Günther C; Tenzer S; Amann K; Billmeier U; Atreya R; Fiorino G; Vetrano S; Danese S; Ekici AB; Wirtz S; Thonn V; Watson AJ; Brakebusch C; Bergö M; Neurath MF; Atreya I
    J Clin Invest; 2016 Feb; 126(2):611-26. PubMed ID: 26752649
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.