BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

396 related articles for article (PubMed ID: 31499260)

  • 1. Synthesis, biological evaluation and in silico modelling studies of 1,3,5-trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors.
    Yamali C; Gul HI; Ece A; Bua S; Angeli A; Sakagami H; Sahin E; Supuran CT
    Bioorg Chem; 2019 Nov; 92():103222. PubMed ID: 31499260
    [TBL] [Abstract][Full Text] [Related]  

  • 2. New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors.
    Gul HI; Yamali C; Sakagami H; Angeli A; Leitans J; Kazaks A; Tars K; Ozgun DO; Supuran CT
    Bioorg Chem; 2018 Apr; 77():411-419. PubMed ID: 29427856
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel 2-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)-1-(1,3,5-triazin-2-ylamino)guanidine derivatives: Inhibition of human carbonic anhydrase cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII, anticancer activity, and molecular modeling studies.
    Żołnowska B; Sławiński J; Szafrański K; Angeli A; Supuran CT; Kawiak A; Wieczór M; Zielińska J; Bączek T; Bartoszewska S
    Eur J Med Chem; 2018 Jan; 143():1931-1941. PubMed ID: 29146134
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dual-tail arylsulfone-based benzenesulfonamides differently match the hydrophobic and hydrophilic halves of human carbonic anhydrases active sites: Selective inhibitors for the tumor-associated hCA IX isoform.
    Ibrahim HS; Allam HA; Mahmoud WR; Bonardi A; Nocentini A; Gratteri P; Ibrahim ES; Abdel-Aziz HA; Supuran CT
    Eur J Med Chem; 2018 May; 152():1-9. PubMed ID: 29684705
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comprehensive study on potent and selective carbonic anhydrase inhibitors: Synthesis, bioactivities and molecular modelling studies of 4-(3-(2-arylidenehydrazine-1-carbonyl)-5-(thiophen-2-yl)-1H-pyrazole-1-yl) benzenesulfonamides.
    Yamali C; Sakagami H; Uesawa Y; Kurosaki K; Satoh K; Masuda Y; Yokose S; Ece A; Bua S; Angeli A; Supuran CT; Gul HI
    Eur J Med Chem; 2021 May; 217():113351. PubMed ID: 33744685
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Investigation of carbonic anhydrase inhibitory effects and cytotoxicities of pyrazole-based hybrids carrying hydrazone and zinc-binding benzenesulfonamide pharmacophores.
    Yamali C; Sakagami H; Satoh K; Bandow K; Uesawa Y; Bua S; Angeli A; Supuran CT; Gul HI
    Bioorg Chem; 2022 Oct; 127():105969. PubMed ID: 35926240
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Insertion of metal carbenes into the anilinic N-H bond of unprotected aminobenzenesulfonamides delivers low nanomolar inhibitors of human carbonic anhydrase IX and XII isoforms.
    Sharonova T; Paramonova P; Kalinin S; Bunev A; Gasanov RЕ; Nocentini A; Sharoyko V; Tennikova TB; Dar'in D; Supuran CT; Krasavin M
    Eur J Med Chem; 2021 Jun; 218():113352. PubMed ID: 33774343
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Application of hydrazino and hydrazido linkers to connect benzenesulfonamides with hydrophilic/phobic tails for targeting the middle region of human carbonic anhydrases active site: Selective inhibitors of hCA IX.
    Allam HA; Fahim SH; F Abo-Ashour M; Nocentini A; Elbakry ME; Abdelrahman MA; Eldehna WM; Ibrahim HS; Supuran CT
    Eur J Med Chem; 2019 Oct; 179():547-556. PubMed ID: 31276899
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, biological activity and multiscale molecular modeling studies of bis-coumarins as selective carbonic anhydrase IX and XII inhibitors with effective cytotoxicity against hepatocellular carcinoma.
    Kurt BZ; Dag A; Doğan B; Durdagi S; Angeli A; Nocentini A; Supuran CT; Sonmez F
    Bioorg Chem; 2019 Jun; 87():838-850. PubMed ID: 31003041
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Anticancer effects of new dibenzenesulfonamides by inducing apoptosis and autophagy pathways and their carbonic anhydrase inhibitory effects on hCA I, hCA II, hCA IX, hCA XII isoenzymes.
    Gul HI; Yamali C; Bulbuller M; Kirmizibayrak PB; Gul M; Angeli A; Bua S; Supuran CT
    Bioorg Chem; 2018 Aug; 78():290-297. PubMed ID: 29621641
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Exploring of tumor-associated carbonic anhydrase isoenzyme IX and XII inhibitory effects and cytotoxicities of the novel N-aryl-1-(4-sulfamoylphenyl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxamides.
    Yamali C; Inci Gul H; Ozli G; Angeli A; Ballar Kirmizibayrak P; Erbaykent Tepedelen B; Sakagami H; Bua S; Supuran CT
    Bioorg Chem; 2021 Oct; 115():105194. PubMed ID: 34365059
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Iodoquinazolinones bearing benzenesulfonamide as human carbonic anhydrase I, II, IX and XII inhibitors: Synthesis, biological evaluation and radiosensitizing activity.
    Soliman AM; Ghorab MM; Bua S; Supuran CT
    Eur J Med Chem; 2020 Aug; 200():112449. PubMed ID: 32485534
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis of novel isoindoline-1,3-dione-based oximes and benzenesulfonamide hydrazones as selective inhibitors of the tumor-associated carbonic anhydrase IX.
    Abdel-Aziz AA; El-Azab AS; Abu El-Enin MA; Almehizia AA; Supuran CT; Nocentini A
    Bioorg Chem; 2018 Oct; 80():706-713. PubMed ID: 30064081
    [TBL] [Abstract][Full Text] [Related]  

  • 14. S-substituted 2-mercaptoquinazolin-4(3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors.
    El-Azab AS; Abdel-Aziz AA; Bua S; Nocentini A; AlSaif NA; Alanazi MM; El-Gendy MA; Ahmed HEA; Supuran CT
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):733-743. PubMed ID: 32189526
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and carbonic anhydrase inhibition activity of benzenesulfonamide-linked novel pyrazoline derivatives.
    Abdel-Aziz AA; El-Azab AS; Bua S; Nocentini A; Abu El-Enin MA; Alanazi MM; AlSaif NA; Hefnawy MM; Supuran CT
    Bioorg Chem; 2019 Jun; 87():425-431. PubMed ID: 30921744
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tailored Tetrasubstituted Imidazole Carrying the Benzenesulfonamide Fragments as Selective Human Carbonic Anhydrase IX/XII Inhibitors.
    Taher ES; Marzouk AA; Abd-Allah WH; Giovannuzzi S; Ibrahim TS; Supuran CT; El Hamd MA; El-Behairy MF
    ChemMedChem; 2024 May; 19(10):e202400004. PubMed ID: 38356418
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Carbonic anhydrase inhibitors. Synthesis of heterocyclic 4-substituted pyridine-3-sulfonamide derivatives and their inhibition of the human cytosolic isozymes I and II and transmembrane tumor-associated isozymes IX and XII.
    Sławiński J; Szafrański K; Vullo D; Supuran CT
    Eur J Med Chem; 2013 Nov; 69():701-10. PubMed ID: 24095761
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Investigation of 3-sulfamoyl coumarins against cancer-related IX and XII isoforms of human carbonic anhydrase as well as cancer cells leads to the discovery of 2-oxo-2H-benzo[h]chromene-3-sulfonamide - A new caspase-activating proapoptotic agent.
    Dar'in D; Kantin G; Kalinin S; Sharonova T; Bunev A; Ostapenko GI; Nocentini A; Sharoyko V; Supuran CT; Krasavin M
    Eur J Med Chem; 2021 Oct; 222():113589. PubMed ID: 34147910
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biological evaluation, radiosensitizing activity and structural insights of novel halogenated quinazoline-sulfonamide conjugates as selective human carbonic anhydrases IX/XII inhibitors.
    Ghorab MM; Soliman AM; Bua S; Supuran CT
    Bioorg Chem; 2021 Feb; 107():104618. PubMed ID: 33485104
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and inhibition potency of novel ureido benzenesulfonamides incorporating GABA as tumor-associated carbonic anhydrase IX and XII inhibitors.
    Ceruso M; Antel S; Scozzafava A; Supuran CT
    J Enzyme Inhib Med Chem; 2016; 31(2):205-11. PubMed ID: 25792500
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.