367 related articles for article (PubMed ID: 31502692)
1. Incorporating Ontogeny in Physiologically Based Pharmacokinetic Modeling to Improve Pediatric Drug Development: What We Know About Developmental Changes in Membrane Transporters.
Cheung KWK; van Groen BD; Burckart GJ; Zhang L; de Wildt SN; Huang SM
J Clin Pharmacol; 2019 Sep; 59 Suppl 1(Suppl 1):S56-S69. PubMed ID: 31502692
[TBL] [Abstract][Full Text] [Related]
2. The Application of Physiologically Based Pharmacokinetic Modeling to Predict the Role of Drug Transporters: Scientific and Regulatory Perspectives.
Pan Y; Hsu V; Grimstein M; Zhang L; Arya V; Sinha V; Grillo JA; Zhao P
J Clin Pharmacol; 2016 Jul; 56 Suppl 7():S122-31. PubMed ID: 27385170
[TBL] [Abstract][Full Text] [Related]
3. Potential implications of DMET ontogeny on the disposition of commonly prescribed drugs in neonatal and pediatric intensive care units.
Naji-Talakar S; Sharma S; Martin LA; Barnhart D; Prasad B
Expert Opin Drug Metab Toxicol; 2021 Mar; 17(3):273-289. PubMed ID: 33256492
[No Abstract] [Full Text] [Related]
4. Physiologically-based pharmacokinetic models for children: Starting to reach maturation?
Verscheijden LFM; Koenderink JB; Johnson TN; de Wildt SN; Russel FGM
Pharmacol Ther; 2020 Jul; 211():107541. PubMed ID: 32246949
[TBL] [Abstract][Full Text] [Related]
5. Predictive Pediatric Modeling and Simulation Using Ontogeny Information.
Ince I; Solodenko J; Frechen S; Dallmann A; Niederalt C; Schlender J; Burghaus R; Lippert J; Willmann S
J Clin Pharmacol; 2019 Sep; 59 Suppl 1():S95-S103. PubMed ID: 31502689
[TBL] [Abstract][Full Text] [Related]
6. Ontogeny of Hepatic Drug Transporters and Relevance to Drugs Used in Pediatrics.
Elmorsi Y; Barber J; Rostami-Hodjegan A
Drug Metab Dispos; 2016 Jul; 44(7):992-8. PubMed ID: 26712821
[TBL] [Abstract][Full Text] [Related]
7. Human Ontogeny of Drug Transporters: Review and Recommendations of the Pediatric Transporter Working Group.
Brouwer KL; Aleksunes LM; Brandys B; Giacoia GP; Knipp G; Lukacova V; Meibohm B; Nigam SK; Rieder M; de Wildt SN;
Clin Pharmacol Ther; 2015 Sep; 98(3):266-87. PubMed ID: 26088472
[TBL] [Abstract][Full Text] [Related]
8. Resurgence in the use of physiologically based pharmacokinetic models in pediatric clinical pharmacology: parallel shift in incorporating the knowledge of biological elements and increased applicability to drug development and clinical practice.
Johnson TN; Rostami-Hodjegan A
Paediatr Anaesth; 2011 Mar; 21(3):291-301. PubMed ID: 20497354
[TBL] [Abstract][Full Text] [Related]
9. Summary of the National Institute of Child Health and Human Development-best pharmaceuticals for Children Act Pediatric Formulation Initiatives Workshop-Pediatric Biopharmaceutics Classification System Working Group.
Abdel-Rahman SM; Amidon GL; Kaul A; Lukacova V; Vinks AA; Knipp GT;
Clin Ther; 2012 Nov; 34(11):S11-24. PubMed ID: 23149009
[TBL] [Abstract][Full Text] [Related]
10. Optimized Renal Transporter Quantification by Using Aquaporin 1 and Aquaporin 2 as Anatomical Markers: Application in Characterizing the Ontogeny of Renal Transporters and Its Correlation with Hepatic Transporters in Paired Human Samples.
Li CY; Hosey-Cojocari C; Basit A; Unadkat JD; Leeder JS; Prasad B
AAPS J; 2019 Jul; 21(5):88. PubMed ID: 31297641
[TBL] [Abstract][Full Text] [Related]
11. Physiologically Based Pharmacokinetic Modeling and Allometric Scaling in Pediatric Drug Development: Where Do We Draw the Line?
Johnson TN; Ke AB
J Clin Pharmacol; 2021 Jun; 61 Suppl 1():S83-S93. PubMed ID: 34185901
[TBL] [Abstract][Full Text] [Related]
12. Physiologically-based Pharmacokinetic (PBPK) Modelling of Transporter Mediated Drug Absorption, Clearance and Drug-drug Interactions.
Taskar KS; Harada I; Alluri RV
Curr Drug Metab; 2021; 22(7):523-531. PubMed ID: 33397250
[TBL] [Abstract][Full Text] [Related]
13. Ontogeny of Hepatic Transporters and Drug-Metabolizing Enzymes in Humans and in Nonclinical Species.
van Groen BD; Nicolaï J; Kuik AC; Van Cruchten S; van Peer E; Smits A; Schmidt S; de Wildt SN; Allegaert K; De Schaepdrijver L; Annaert P; Badée J
Pharmacol Rev; 2021 Apr; 73(2):597-678. PubMed ID: 33608409
[TBL] [Abstract][Full Text] [Related]
14. The Influence of Drug Properties and Ontogeny of Transporters on Pediatric Renal Clearance through Glomerular Filtration and Active Secretion: a Simulation-Based Study.
Cristea S; Krekels EHJ; Rostami-Hodjegan A; Allegaert K; Knibbe CAJ
AAPS J; 2020 Jun; 22(4):87. PubMed ID: 32566984
[TBL] [Abstract][Full Text] [Related]
15. Predictive Performance of Physiologically Based Pharmacokinetic and Population Pharmacokinetic Modeling of Renally Cleared Drugs in Children.
Zhou W; Johnson TN; Xu H; Cheung S; Bui KH; Li J; Al-Huniti N; Zhou D
CPT Pharmacometrics Syst Pharmacol; 2016 Sep; 5(9):475-83. PubMed ID: 27566992
[TBL] [Abstract][Full Text] [Related]
16. The use of PBPK modeling across the pediatric age range using propofol as a case.
Michelet R; Van Bocxlaer J; Allegaert K; Vermeulen A
J Pharmacokinet Pharmacodyn; 2018 Dec; 45(6):765-785. PubMed ID: 30298439
[TBL] [Abstract][Full Text] [Related]
17. PBPK modeling of intestinal and liver enzymes and transporters in drug absorption and sequential metabolism.
Fan J; Chen S; Chow EC; Pang KS
Curr Drug Metab; 2010 Nov; 11(9):743-61. PubMed ID: 21189137
[TBL] [Abstract][Full Text] [Related]
18. Model qualification of the PK-Sim® pediatric module for pediatric exposure assessment of CYP450 metabolized compounds.
Yun YE; Edginton AN
J Toxicol Environ Health A; 2019; 82(14):789-814. PubMed ID: 31405354
[TBL] [Abstract][Full Text] [Related]
19. Estimation of Ontogeny Functions for Renal Transporters Using a Combined Population Pharmacokinetic and Physiology-Based Pharmacokinetic Approach: Application to OAT1,3.
Cristea S; Krekels EHJ; Allegaert K; De Paepe P; de Jaeger A; De Cock P; Knibbe CAJ
AAPS J; 2021 May; 23(3):65. PubMed ID: 33948771
[TBL] [Abstract][Full Text] [Related]
20. Prediction of Clearance in Neonates and Infants (≤ 3 Months of Age) for Drugs That Are Glucuronidated: A Comparative Study Between Allometric Scaling and Physiologically Based Pharmacokinetic Modeling.
Mahmood I; Ahmad T; Mansoor N; Sharib SM
J Clin Pharmacol; 2017 Apr; 57(4):476-483. PubMed ID: 27704554
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]