BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

248 related articles for article (PubMed ID: 31502857)

  • 1. Assays to Interrogate the Ability of Compounds to Inhibit the AF-2 or AF-1 Transactivation Domains of the Androgen Receptor.
    Fancher AT; Hua Y; Strock CJ; Johnston PA
    Assay Drug Dev Technol; 2019; 17(8):364-386. PubMed ID: 31502857
    [TBL] [Abstract][Full Text] [Related]  

  • 2. High-Content Screening Campaign to Identify Compounds That Inhibit or Disrupt Androgen Receptor-Transcriptional Intermediary Factor 2 Protein-Protein Interactions for the Treatment of Prostate Cancer.
    Fancher AT; Hua Y; Camarco DP; Close DA; Strock CJ; Johnston PA
    Assay Drug Dev Technol; 2018; 16(6):297-319. PubMed ID: 30109944
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of allosteric modulators that disrupt androgen receptor co-activator protein-protein interactions to alter transactivation-Drug leads for metastatic castration resistant prostate cancer.
    Fancher AT; Hua Y; Close DA; Xu W; McDermott LA; Strock CJ; Santiago U; Camacho CJ; Johnston PA
    SLAS Discov; 2023 Oct; 28(7):325-343. PubMed ID: 37549772
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sintokamide A Is a Novel Antagonist of Androgen Receptor That Uniquely Binds Activation Function-1 in Its Amino-terminal Domain.
    Banuelos CA; Tavakoli I; Tien AH; Caley DP; Mawji NR; Li Z; Wang J; Yang YC; Imamura Y; Yan L; Wen JG; Andersen RJ; Sadar MD
    J Biol Chem; 2016 Oct; 291(42):22231-22243. PubMed ID: 27576691
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting Androgen Receptor Activation Function-1 with EPI to Overcome Resistance Mechanisms in Castration-Resistant Prostate Cancer.
    Yang YC; Banuelos CA; Mawji NR; Wang J; Kato M; Haile S; McEwan IJ; Plymate S; Sadar MD
    Clin Cancer Res; 2016 Sep; 22(17):4466-77. PubMed ID: 27140928
    [TBL] [Abstract][Full Text] [Related]  

  • 6. High-content positional biosensor screening assay for compounds to prevent or disrupt androgen receptor and transcriptional intermediary factor 2 protein-protein interactions.
    Hua Y; Shun TY; Strock CJ; Johnston PA
    Assay Drug Dev Technol; 2014 Sep; 12(7):395-418. PubMed ID: 25181412
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reconfiguring the AR-TIF2 Protein-Protein Interaction HCS Assay in Prostate Cancer Cells and Characterizing the Hits from a LOPAC Screen.
    Fancher AT; Hua Y; Camarco DP; Close DA; Strock CJ; Johnston PA
    Assay Drug Dev Technol; 2016 Oct; 14(8):453-477. PubMed ID: 27606620
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeted disruption of the p160 coactivator interface of androgen receptor (AR) selectively inhibits AR activity in both androgen-dependent and castration-resistant AR-expressing prostate cancer cells.
    Nakka M; Agoulnik IU; Weigel NL
    Int J Biochem Cell Biol; 2013 Apr; 45(4):763-72. PubMed ID: 23270728
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of niphatenones that inhibit androgen receptor N-terminal domain.
    Banuelos CA; Lal A; Tien AH; Shah N; Yang YC; Mawji NR; Meimetis LG; Park J; Kunzhong J; Andersen RJ; Sadar MD
    PLoS One; 2014; 9(9):e107991. PubMed ID: 25268119
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development and Implementation of a High-Throughput High-Content Screening Assay to Identify Inhibitors of Androgen Receptor Nuclear Localization in Castration-Resistant Prostate Cancer Cells.
    Johnston PA; Nguyen MM; Dar JA; Ai J; Wang Y; Masoodi KZ; Shun T; Shinde S; Camarco DP; Hua Y; Huryn DM; Wilson GM; Lazo JS; Nelson JB; Wipf P; Wang Z
    Assay Drug Dev Technol; 2016 May; 14(4):226-39. PubMed ID: 27187604
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Androgen receptors in hormone-dependent and castration-resistant prostate cancer.
    Shafi AA; Yen AE; Weigel NL
    Pharmacol Ther; 2013 Dec; 140(3):223-38. PubMed ID: 23859952
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting the Hsp40/Hsp70 Chaperone Axis as a Novel Strategy to Treat Castration-Resistant Prostate Cancer.
    Moses MA; Kim YS; Rivera-Marquez GM; Oshima N; Watson MJ; Beebe KE; Wells C; Lee S; Zuehlke AD; Shao H; Bingman WE; Kumar V; Malhotra SV; Weigel NL; Gestwicki JE; Trepel JB; Neckers LM
    Cancer Res; 2018 Jul; 78(14):4022-4035. PubMed ID: 29764864
    [TBL] [Abstract][Full Text] [Related]  

  • 13. High Content Positional Biosensor Assay to Screen for Compounds that Prevent or Disrupt Androgen Receptor and Transcription Intermediary Factor 2 Protein-Protein Interactions.
    Hua Y; Camarco DP; Strock CJ; Johnston PA
    Methods Mol Biol; 2018; 1683():211-227. PubMed ID: 29082495
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Androgen receptor: what we know and what we expect in castration-resistant prostate cancer.
    Cai Z; Chen W; Zhang J; Li H
    Int Urol Nephrol; 2018 Oct; 50(10):1753-1764. PubMed ID: 30128923
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolically stable diphenylamine derivatives suppress androgen receptor and BET protein in prostate cancer.
    Yu J; Zhou P; Du W; Xu R; Yan G; Deng Y; Li X; Chen Y
    Biochem Pharmacol; 2020 Jul; 177():113946. PubMed ID: 32247852
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor.
    Andersen RJ; Mawji NR; Wang J; Wang G; Haile S; Myung JK; Watt K; Tam T; Yang YC; BaƱuelos CA; Williams DE; McEwan IJ; Wang Y; Sadar MD
    Cancer Cell; 2010 Jun; 17(6):535-46. PubMed ID: 20541699
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibiting androgen receptor splice variants with cysteine-selective irreversible covalent inhibitors to treat prostate cancer.
    Thiyagarajan T; Ponnusamy S; Hwang DJ; He Y; Asemota S; Young KL; Johnson DL; Bocharova V; Zhou W; Jain AK; Petricoin EF; Yin Z; Pfeffer LM; Miller DD; Narayanan R
    Proc Natl Acad Sci U S A; 2023 Jan; 120(1):e2211832120. PubMed ID: 36577061
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.
    Dalal K; Roshan-Moniri M; Sharma A; Li H; Ban F; Hessein M; Hsing M; Singh K; LeBlanc E; Dehm S; Tomlinson Guns ES; Cherkasov A; Rennie PS
    J Biol Chem; 2014 Sep; 289(38):26417-26429. PubMed ID: 25086042
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Androgen receptor splice variants are resistant to inhibitors of Hsp90 and FKBP52, which alter androgen receptor activity and expression.
    Shafi AA; Cox MB; Weigel NL
    Steroids; 2013 Jun; 78(6):548-54. PubMed ID: 23380368
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of novel androgen receptor degrading agents to treat advanced prostate cancer.
    Wu H; Ren J; Zhao L; Li Z; Ye W; Yang Y; Wang J; Bian J
    Eur J Med Chem; 2021 May; 217():113376. PubMed ID: 33756125
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.