These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

311 related articles for article (PubMed ID: 31509404)

  • 1. Photoinduced Electron Transfer in a Radical SAM Enzyme Generates an
    Yang H; Impano S; Shepard EM; James CD; Broderick WE; Broderick JB; Hoffman BM
    J Am Chem Soc; 2019 Oct; 141(40):16117-16124. PubMed ID: 31509404
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Active-Site Controlled, Jahn-Teller Enabled Regioselectivity in Reductive S-C Bond Cleavage of
    Impano S; Yang H; Jodts RJ; Pagnier A; Swimley R; McDaniel EC; Shepard EM; Broderick WE; Broderick JB; Hoffman BM
    J Am Chem Soc; 2021 Jan; 143(1):335-348. PubMed ID: 33372786
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ENDOR Spectroscopy Reveals the "Free" 5'-Deoxyadenosyl Radical in a Radical SAM Enzyme Active Site Actually is Chaperoned by Close Interaction with the Methionine-Bound [4Fe-4S]
    Yang H; Ho MB; Lundahl MN; Mosquera MA; Broderick WE; Broderick JB; Hoffman BM
    J Am Chem Soc; 2024 Feb; 146(6):3710-3720. PubMed ID: 38308759
    [No Abstract]   [Full Text] [Related]  

  • 4. Radical SAM Enzyme Spore Photoproduct Lyase: Properties of the Ω Organometallic Intermediate and Identification of Stable Protein Radicals Formed during Substrate-Free Turnover.
    Pagnier A; Yang H; Jodts RJ; James CD; Shepard EM; Impano S; Broderick WE; Hoffman BM; Broderick JB
    J Am Chem Soc; 2020 Oct; 142(43):18652-18660. PubMed ID: 32966073
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanism of Radical Initiation in the Radical S-Adenosyl-l-methionine Superfamily.
    Broderick WE; Hoffman BM; Broderick JB
    Acc Chem Res; 2018 Nov; 51(11):2611-2619. PubMed ID: 30346729
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pyruvate formate-lyase activating enzyme: The catalytically active 5'-deoxyadenosyl radical caught in the act of H-atom abstraction.
    Lundahl MN; Yang H; Broderick WE; Hoffman BM; Broderick JB
    Proc Natl Acad Sci U S A; 2023 Nov; 120(47):e2314696120. PubMed ID: 37956301
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Radical SAM enzymes: Nature's choice for radical reactions.
    Broderick JB; Broderick WE; Hoffman BM
    FEBS Lett; 2023 Jan; 597(1):92-101. PubMed ID: 36251330
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Radical SAM catalysis via an organometallic intermediate with an Fe-[5'-C]-deoxyadenosyl bond.
    Horitani M; Shisler K; Broderick WE; Hutcheson RU; Duschene KS; Marts AR; Hoffman BM; Broderick JB
    Science; 2016 May; 352(6287):822-5. PubMed ID: 27174986
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization by ENDOR Spectroscopy of the Iron-Alkyl Bond in a Synthetic Counterpart of Organometallic Intermediates in Radical SAM Enzymes.
    Ho MB; Jodts RJ; Kim Y; McSkimming A; Suess DLM; Hoffman BM
    J Am Chem Soc; 2022 Sep; 144(38):17642-17650. PubMed ID: 36108299
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanism of Radical Initiation in the Radical SAM Enzyme Superfamily.
    Hoffman BM; Broderick WE; Broderick JB
    Annu Rev Biochem; 2023 Jun; 92():333-349. PubMed ID: 37018846
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Electron-nuclear double resonance spectroscopic evidence that S-adenosylmethionine binds in contact with the catalytically active [4Fe-4S](+) cluster of pyruvate formate-lyase activating enzyme.
    Walsby CJ; Hong W; Broderick WE; Cheek J; Ortillo D; Broderick JB; Hoffman BM
    J Am Chem Soc; 2002 Mar; 124(12):3143-51. PubMed ID: 11902903
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Paradigm Shift for Radical S-Adenosyl-l-methionine Reactions: The Organometallic Intermediate Ω Is Central to Catalysis.
    Byer AS; Yang H; McDaniel EC; Kathiresan V; Impano S; Pagnier A; Watts H; Denler C; Vagstad AL; Piel J; Duschene KS; Shepard EM; Shields TP; Scott LG; Lilla EA; Yokoyama K; Broderick WE; Hoffman BM; Broderick JB
    J Am Chem Soc; 2018 Jul; 140(28):8634-8638. PubMed ID: 29954180
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Trapping and Electron Paramagnetic Resonance Characterization of the 5'dAdo
    Sayler RI; Stich TA; Joshi S; Cooper N; Shaw JT; Begley TP; Tantillo DJ; Britt RD
    ACS Cent Sci; 2019 Nov; 5(11):1777-1785. PubMed ID: 31807679
    [No Abstract]   [Full Text] [Related]  

  • 14. Coordination and mechanism of reversible cleavage of S-adenosylmethionine by the [4Fe-4S] center in lysine 2,3-aminomutase.
    Chen D; Walsby C; Hoffman BM; Frey PA
    J Am Chem Soc; 2003 Oct; 125(39):11788-9. PubMed ID: 14505379
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Substrate-Dependent Cleavage Site Selection by Unconventional Radical S-Adenosylmethionine Enzymes in Diphthamide Biosynthesis.
    Dong M; Horitani M; Dzikovski B; Freed JH; Ealick SE; Hoffman BM; Lin H
    J Am Chem Soc; 2017 Apr; 139(16):5680-5683. PubMed ID: 28383907
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural studies of the interaction of S-adenosylmethionine with the [4Fe-4S] clusters in biotin synthase and pyruvate formate-lyase activating enzyme.
    Cosper MM; Cosper NJ; Hong W; Shokes JE; Broderick WE; Broderick JB; Johnson MK; Scott RA
    Protein Sci; 2003 Jul; 12(7):1573-7. PubMed ID: 12824504
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Making and breaking carbon-carbon bonds in class C radical SAM methyltransferases.
    Brimberry MA; Mathew L; Lanzilotta W
    J Inorg Biochem; 2022 Jan; 226():111636. PubMed ID: 34717253
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An anchoring role for FeS clusters: chelation of the amino acid moiety of S-adenosylmethionine to the unique iron site of the [4Fe-4S] cluster of pyruvate formate-lyase activating enzyme.
    Walsby CJ; Ortillo D; Broderick WE; Broderick JB; Hoffman BM
    J Am Chem Soc; 2002 Sep; 124(38):11270-1. PubMed ID: 12236732
    [TBL] [Abstract][Full Text] [Related]  

  • 19.
    Lundahl MN; Sarksian R; Yang H; Jodts RJ; Pagnier A; Smith DF; Mosquera MA; van der Donk WA; Hoffman BM; Broderick WE; Broderick JB
    J Am Chem Soc; 2022 Mar; 144(11):5087-5098. PubMed ID: 35258967
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biochemical and kinetic characterization of radical S-adenosyl-L-methionine enzyme HydG.
    Driesener RC; Duffus BR; Shepard EM; Bruzas IR; Duschene KS; Coleman NJ; Marrison AP; Salvadori E; Kay CW; Peters JW; Broderick JB; Roach PL
    Biochemistry; 2013 Dec; 52(48):8696-707. PubMed ID: 24206022
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.