179 related articles for article (PubMed ID: 31509771)
1. Effect of mutations in porcine CYB5A and CYP17A1 on the metabolism of pregnenolone.
Squires EJ; Gray MA; Lou Y
J Steroid Biochem Mol Biol; 2019 Dec; 195():105469. PubMed ID: 31509771
[TBL] [Abstract][Full Text] [Related]
2. Kinetic processivity of the two-step oxidations of progesterone and pregnenolone to androgens by human cytochrome P450 17A1.
Gonzalez E; Guengerich FP
J Biol Chem; 2017 Aug; 292(32):13168-13185. PubMed ID: 28684414
[TBL] [Abstract][Full Text] [Related]
3. The role of porcine cytochrome b5A and cytochrome b5B in the regulation of cytochrome P45017A1 activities.
Billen MJ; Squires EJ
J Steroid Biochem Mol Biol; 2009 Jan; 113(1-2):98-104. PubMed ID: 19101629
[TBL] [Abstract][Full Text] [Related]
4. SPR-Based study of affinity of cytochrome P450s / redox partners interactions modulated by steroidal substrates.
Ershov PV; Yablokov ЕO; Florinskaya AV; Mezentsev YV; Kaluzhskiy LА; Tumilovich AM; Gilep АА; Usanov SA; Ivanov АS
J Steroid Biochem Mol Biol; 2019 Mar; 187():124-129. PubMed ID: 30468857
[TBL] [Abstract][Full Text] [Related]
5. Substrate-modulated cytochrome P450 17A1 and cytochrome b5 interactions revealed by NMR.
Estrada DF; Laurence JS; Scott EE
J Biol Chem; 2013 Jun; 288(23):17008-17018. PubMed ID: 23620596
[TBL] [Abstract][Full Text] [Related]
6. Efficiency of the sulfate pathway in comparison to the Δ4- and Δ5-pathway of steroidogenesis in the porcine testis.
Klymiuk MC; Neunzig J; Bernhardt R; Sánchez-Guijo A; Hartmann MF; Wudy SA; Schuler G
J Steroid Biochem Mol Biol; 2018 May; 179():64-72. PubMed ID: 29107177
[TBL] [Abstract][Full Text] [Related]
7. Conversion of pregnenolone to DHEA by human 17alpha-hydroxylase/17, 20-lyase (P450c17). Evidence that DHEA is produced from the released intermediate, 17alpha-hydroxypregnenolone.
Soucy P; Luu-The V
Eur J Biochem; 2000 Jun; 267(11):3243-7. PubMed ID: 10824109
[TBL] [Abstract][Full Text] [Related]
8. A missense mutation in the human cytochrome b5 gene causes 46,XY disorder of sex development due to true isolated 17,20 lyase deficiency.
Idkowiak J; Randell T; Dhir V; Patel P; Shackleton CH; Taylor NF; Krone N; Arlt W
J Clin Endocrinol Metab; 2012 Mar; 97(3):E465-75. PubMed ID: 22170710
[TBL] [Abstract][Full Text] [Related]
9. Cytochrome b5 Activates the 17,20-Lyase Activity of Human Cytochrome P450 17A1 by Increasing the Coupling of NADPH Consumption to Androgen Production.
Peng HM; Im SC; Pearl NM; Turcu AF; Rege J; Waskell L; Auchus RJ
Biochemistry; 2016 Aug; 55(31):4356-65. PubMed ID: 27426448
[TBL] [Abstract][Full Text] [Related]
10. Hydroxylation and lyase reactions of steroids catalyzed by mouse cytochrome P450 17A1 (Cyp17a1).
Lee SG; Kim V; Lee GH; Kim C; Jeong E; Guengerich FP; Kim D
J Inorg Biochem; 2023 Mar; 240():112085. PubMed ID: 36640554
[TBL] [Abstract][Full Text] [Related]
11. Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor. Role of recombinant cytochrome b5 and P450 reductase.
Soucy P; Lacoste L; Luu-The V
Eur J Biochem; 2003 Mar; 270(6):1349-55. PubMed ID: 12631293
[TBL] [Abstract][Full Text] [Related]
12. Age-dependent Increases in Adrenal Cytochrome b5 and Serum 5-Androstenediol-3-sulfate.
Rege J; Karashima S; Lerario AM; Smith JM; Auchus RJ; Kasa-Vubu JZ; Sasano H; Nakamura Y; White PC; Rainey WE
J Clin Endocrinol Metab; 2016 Dec; 101(12):4585-4593. PubMed ID: 27623070
[TBL] [Abstract][Full Text] [Related]
13. Role of cytochrome b5 in the modulation of the enzymatic activities of cytochrome P450 17α-hydroxylase/17,20-lyase (P450 17A1).
Bhatt MR; Khatri Y; Rodgers RJ; Martin LL
J Steroid Biochem Mol Biol; 2017 Jun; 170():2-18. PubMed ID: 26976652
[TBL] [Abstract][Full Text] [Related]
14. A Homodimer Model Can Resolve the Conundrum as to How Cytochrome P450 Oxidoreductase and Cytochrome b5 Compete for the Same Binding Site on Cytochrome P450c17.
Holien JK; Parker MW; Conley AJ; Corbin CJ; Rodgers RJ; Martin LL
Curr Protein Pept Sci; 2017; 18(5):515-521. PubMed ID: 28000554
[TBL] [Abstract][Full Text] [Related]
15. Steroid 17-hydroxylase and 17,20-lyase deficiencies, genetic and pharmacologic.
Auchus RJ
J Steroid Biochem Mol Biol; 2017 Jan; 165(Pt A):71-78. PubMed ID: 26862015
[TBL] [Abstract][Full Text] [Related]
16. Cytochrome P450c17 from porcine and bovine adrenal catalyses the formation of 5,16-androstadien-3 beta-ol from pregnenolone in the presence of cytochrome b5.
Meadus WJ; Mason JI; Squires EJ
J Steroid Biochem Mol Biol; 1993 Nov; 46(5):565-72. PubMed ID: 8240978
[TBL] [Abstract][Full Text] [Related]
17. Assessment of the ability of type 2 cytochrome b5 to modulate 17,20-lyase activity of human P450c17.
Soucy P; Luu-The V
J Steroid Biochem Mol Biol; 2002 Jan; 80(1):71-5. PubMed ID: 11867265
[TBL] [Abstract][Full Text] [Related]
18. Active site proton delivery and the lyase activity of human CYP17A1.
Khatri Y; Gregory MC; Grinkova YV; Denisov IG; Sligar SG
Biochem Biophys Res Commun; 2014 Jan; 443(1):179-84. PubMed ID: 24299954
[TBL] [Abstract][Full Text] [Related]
19. Comparison of the 17 alpha-hydroxylase/C17,20-lyase activities of porcine, guinea pig and bovine P450c17 using purified recombinant fusion proteins containing P450c17 linked to NADPH-P450 reductase.
Shet MS; Fisher CW; Tremblay Y; Belanger A; Conley AJ; Mason JI; Estabrook RW
Drug Metab Rev; 2007; 39(2-3):289-307. PubMed ID: 17786622
[TBL] [Abstract][Full Text] [Related]
20. A steroidogenic pathway for sulfonated steroids: the metabolism of pregnenolone sulfate.
Neunzig J; Sánchez-Guijo A; Mosa A; Hartmann MF; Geyer J; Wudy SA; Bernhardt R
J Steroid Biochem Mol Biol; 2014 Oct; 144 Pt B():324-33. PubMed ID: 25038322
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]