296 related articles for article (PubMed ID: 31511320)
1. HNRNPH1-dependent splicing of a fusion oncogene reveals a targetable RNA G-quadruplex interaction.
Neckles C; Boer RE; Aboreden N; Cross AM; Walker RL; Kim BH; Kim S; Schneekloth JS; Caplen NJ
RNA; 2019 Dec; 25(12):1731-1750. PubMed ID: 31511320
[TBL] [Abstract][Full Text] [Related]
2. Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma.
Grohar PJ; Kim S; Rangel Rivera GO; Sen N; Haddock S; Harlow ML; Maloney NK; Zhu J; O'Neill M; Jones TL; Huppi K; Grandin M; Gehlhaus K; Klumpp-Thomas CA; Buehler E; Helman LJ; Martin SE; Caplen NJ
Cell Rep; 2016 Jan; 14(3):598-610. PubMed ID: 26776507
[TBL] [Abstract][Full Text] [Related]
3. Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing.
Selvanathan SP; Graham GT; Erkizan HV; Dirksen U; Natarajan TG; Dakic A; Yu S; Liu X; Paulsen MT; Ljungman ME; Wu CH; Lawlor ER; Üren A; Toretsky JA
Proc Natl Acad Sci U S A; 2015 Mar; 112(11):E1307-16. PubMed ID: 25737553
[TBL] [Abstract][Full Text] [Related]
4. Repression of the gene encoding the TGF-beta type II receptor is a major target of the EWS-FLI1 oncoprotein.
Hahm KB; Cho K; Lee C; Im YH; Chang J; Choi SG; Sorensen PH; Thiele CJ; Kim SJ
Nat Genet; 1999 Oct; 23(2):222-7. PubMed ID: 10508522
[TBL] [Abstract][Full Text] [Related]
5. HNRNPH1 destabilizes the G-quadruplex structures formed by G-rich RNA sequences that regulate the alternative splicing of an oncogenic fusion transcript.
Vo T; Brownmiller T; Hall K; Jones TL; Choudhari S; Grammatikakis I; Ludwig KR; Caplen NJ
Nucleic Acids Res; 2022 Jun; 50(11):6474-6496. PubMed ID: 35639772
[TBL] [Abstract][Full Text] [Related]
6. Identification of various exon combinations of the ews/fli1 translocation: an optimized RT-PCR method for paraffin embedded tissue -- a report by the CWS-study group.
Stegmaier S; Leuschner I; Aakcha-Rudel E; Münch P; Kazanowska B; Bekassy A; Treuner J; Koscielniak E
Klin Padiatr; 2004; 216(6):315-22. PubMed ID: 15565546
[TBL] [Abstract][Full Text] [Related]
7. BET bromodomain inhibitors suppress EWS-FLI1-dependent transcription and the IGF1 autocrine mechanism in Ewing sarcoma.
Loganathan SN; Tang N; Fleming JT; Ma Y; Guo Y; Borinstein SC; Chiang C; Wang J
Oncotarget; 2016 Jul; 7(28):43504-43517. PubMed ID: 27259270
[TBL] [Abstract][Full Text] [Related]
8. ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion.
Saulnier O; Guedri-Idjouadiene K; Aynaud MM; Chakraborty A; Bruyr J; Pineau J; O'Grady T; Mirabeau O; Grossetête S; Galvan B; Claes M; Al Oula Hassoun Z; Sadacca B; Laud K; Zaïdi S; Surdez D; Baulande S; Rambout X; Tirode F; Dutertre M; Delattre O; Dequiedt F
Nucleic Acids Res; 2021 May; 49(9):5038-5056. PubMed ID: 34009296
[TBL] [Abstract][Full Text] [Related]
9. Transcriptomic and immunophenotypic characterization of two cases of adamantinoma-like Ewing sarcoma of the thyroid gland.
Chatzopoulos K; Davila JI; Fadra N; Jackson RA; Minn KT; Sotiriou S; Oliveira AM; Erickson LA; Halling KC; Rumilla KM; Rivera M
Histopathology; 2023 Sep; 83(3):426-434. PubMed ID: 37195579
[TBL] [Abstract][Full Text] [Related]
10. Multiple chromosomal mechanisms generate an EWS/FLI1 or an EWS/ERG fusion gene in Ewing tumors.
Desmaze C; Brizard F; Turc-Carel C; Melot T; Delattre O; Thomas G; Aurias A
Cancer Genet Cytogenet; 1997 Aug; 97(1):12-9. PubMed ID: 9242212
[TBL] [Abstract][Full Text] [Related]
11. Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis.
Marques Howarth M; Simpson D; Ngok SP; Nieves B; Chen R; Siprashvili Z; Vaka D; Breese MR; Crompton BD; Alexe G; Hawkins DS; Jacobson D; Brunner AL; West R; Mora J; Stegmaier K; Khavari P; Sweet-Cordero EA
J Clin Invest; 2014 Dec; 124(12):5275-90. PubMed ID: 25401475
[TBL] [Abstract][Full Text] [Related]
12. Fusion protein EWS-FLI1 is incorporated into a protein granule in cells.
Ahmed NS; Harrell LM; Wieland DR; Lay MA; Thompson VF; Schwartz JC
RNA; 2021 May; 27(8):920-32. PubMed ID: 34035145
[TBL] [Abstract][Full Text] [Related]
13. Genotoxic stress inhibits Ewing sarcoma cell growth by modulating alternative pre-mRNA processing of the RNA helicase DHX9.
Fidaleo M; Svetoni F; Volpe E; Miñana B; Caporossi D; Paronetto MP
Oncotarget; 2015 Oct; 6(31):31740-57. PubMed ID: 26450900
[TBL] [Abstract][Full Text] [Related]
14. PI3K/AKT signaling modulates transcriptional expression of EWS/FLI1 through specificity protein 1.
Giorgi C; Boro A; Rechfeld F; Lopez-Garcia LA; Gierisch ME; Schäfer BW; Niggli FK
Oncotarget; 2015 Oct; 6(30):28895-910. PubMed ID: 26336820
[TBL] [Abstract][Full Text] [Related]
15. The orphan nuclear receptor DAX1 is up-regulated by the EWS/FLI1 oncoprotein and is highly expressed in Ewing tumors.
Mendiola M; Carrillo J; García E; Lalli E; Hernández T; de Alava E; Tirode F; Delattre O; García-Miguel P; López-Barea F; Pestaña A; Alonso J
Int J Cancer; 2006 Mar; 118(6):1381-9. PubMed ID: 16206264
[TBL] [Abstract][Full Text] [Related]
16. Single-cell RNA profiling identifies diverse cellular responses to EWSR1/FLI1 downregulation in Ewing sarcoma cells.
Khoogar R; Li F; Chen Y; Ignatius M; Lawlor ER; Kitagawa K; Huang TH; Phelps DA; Houghton PJ
Cell Oncol (Dordr); 2022 Feb; 45(1):19-40. PubMed ID: 34997546
[TBL] [Abstract][Full Text] [Related]
17. Multiple splice variants of EWSR1-ETS fusion transcripts co-existing in the Ewing sarcoma family of tumors.
Patócs B; Németh K; Garami M; Arató G; Kovalszky I; Szendrői M; Fekete G
Cell Oncol (Dordr); 2013 Jun; 36(3):191-200. PubMed ID: 23494411
[TBL] [Abstract][Full Text] [Related]
18. EWSR1-FLI1 Activation of the Cancer/Testis Antigen FATE1 Promotes Ewing Sarcoma Survival.
Gallegos ZR; Taus P; Gibbs ZA; McGlynn K; Gomez NC; Davis I; Whitehurst AW
Mol Cell Biol; 2019 Jul; 39(14):. PubMed ID: 31036566
[TBL] [Abstract][Full Text] [Related]
19. RING1B recruits EWSR1-FLI1 and cooperates in the remodeling of chromatin necessary for Ewing sarcoma tumorigenesis.
Sánchez-Molina S; Figuerola-Bou E; Blanco E; Sánchez-Jiménez M; Táboas P; Gómez S; Ballaré C; García-Domínguez DJ; Prada E; Hontecillas-Prieto L; M Carcaboso Á; Tirado ÓM; Hernández-Muñoz I; de Álava E; Lavarino C; Di Croce L; Mora J
Sci Adv; 2020 Oct; 6(43):. PubMed ID: 33097530
[TBL] [Abstract][Full Text] [Related]
20. EWS-FLI1, EWS-ERG, and EWS-ETV1 oncoproteins of Ewing tumor family all suppress transcription of transforming growth factor beta type II receptor gene.
Im YH; Kim HT; Lee C; Poulin D; Welford S; Sorensen PH; Denny CT; Kim SJ
Cancer Res; 2000 Mar; 60(6):1536-40. PubMed ID: 10749119
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]