BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 31512408)

  • 1. USP9X stabilizes BRCA1 and confers resistance to DNA-damaging agents in human cancer cells.
    Lu Q; Zhang FL; Lu DY; Shao ZM; Li DQ
    Cancer Med; 2019 Nov; 8(15):6730-6740. PubMed ID: 31512408
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Deubiquitinase ubiquitin-specific protease 9X regulates the stability and function of E3 ubiquitin ligase ring finger protein 115 in breast cancer cells.
    Lu Q; Lu D; Shao ZM; Li DQ
    Cancer Sci; 2019 Apr; 110(4):1268-1278. PubMed ID: 30689267
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Non-canonical regulation of homologous recombination DNA repair by the USP9X deubiquitylase.
    O'Dea R; Santocanale C
    J Cell Sci; 2020 Feb; 133(3):. PubMed ID: 31964704
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting deubiquitinase activity with a novel small-molecule inhibitor as therapy for B-cell malignancies.
    Peterson LF; Sun H; Liu Y; Potu H; Kandarpa M; Ermann M; Courtney SM; Young M; Showalter HD; Sun D; Jakubowiak A; Malek SN; Talpaz M; Donato NJ
    Blood; 2015 Jun; 125(23):3588-97. PubMed ID: 25814533
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival.
    Schwickart M; Huang X; Lill JR; Liu J; Ferrando R; French DM; Maecker H; O'Rourke K; Bazan F; Eastham-Anderson J; Yue P; Dornan D; Huang DC; Dixit VM
    Nature; 2010 Jan; 463(7277):103-7. PubMed ID: 20023629
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of USP9X induces apoptosis in FLT3-ITD-positive AML cells cooperatively by inhibiting the mutant kinase through aggresomal translocation and inducing oxidative stress.
    Akiyama H; Umezawa Y; Ishida S; Okada K; Nogami A; Miura O
    Cancer Lett; 2019 Jul; 453():84-94. PubMed ID: 30946869
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation.
    Xie Y; Avello M; Schirle M; McWhinnie E; Feng Y; Bric-Furlong E; Wilson C; Nathans R; Zhang J; Kirschner MW; Huang SM; Cong F
    J Biol Chem; 2013 Feb; 288(5):2976-85. PubMed ID: 23184937
    [TBL] [Abstract][Full Text] [Related]  

  • 8. USP9X deubiquitinates ALDH1A3 and maintains mesenchymal identity in glioblastoma stem cells.
    Chen Z; Wang HW; Wang S; Fan L; Feng S; Cai X; Peng C; Wu X; Lu J; Chen D; Chen Y; Wu W; Lu D; Liu N; You Y; Wang H
    J Clin Invest; 2019 Apr; 129(5):2043-2055. PubMed ID: 30958800
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A Novel BRCA1-Associated Protein-1 Isoform Affects Response of Mesothelioma Cells to Drugs Impairing BRCA1-Mediated DNA Repair.
    Parrotta R; Okonska A; Ronner M; Weder W; Stahel R; Penengo L; Felley-Bosco E
    J Thorac Oncol; 2017 Aug; 12(8):1309-1319. PubMed ID: 28389374
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Context-dependent function of the deubiquitinating enzyme USP9X in pancreatic ductal adenocarcinoma.
    Cox JL; Wilder PJ; Wuebben EL; Ouellette MM; Hollingsworth MA; Rizzino A
    Cancer Biol Ther; 2014 Aug; 15(8):1042-52. PubMed ID: 24841553
    [TBL] [Abstract][Full Text] [Related]  

  • 11. BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis.
    Salas-Lloret D; García-Rodríguez N; Soto-Hidalgo E; González-Vinceiro L; Espejo-Serrano C; Giebel L; Mateos-Martín ML; de Ru AH; van Veelen PA; Huertas P; Vertegaal ACO; González-Prieto R
    Nat Commun; 2024 May; 15(1):4292. PubMed ID: 38769345
    [TBL] [Abstract][Full Text] [Related]  

  • 12. USP9X destabilizes pVHL and promotes cell proliferation.
    Zhang C; Peng Z; Zhu M; Wang P; Du X; Li X; Liu Y; Jin Y; McNutt MA; Yin Y
    Oncotarget; 2016 Sep; 7(37):60519-60534. PubMed ID: 27517496
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of the deubiquitinase USP9x induces pre-B cell homeobox 1 (PBX1) degradation and thereby stimulates prostate cancer cell apoptosis.
    Liu Y; Xu X; Lin P; He Y; Zhang Y; Cao B; Zhang Z; Sethi G; Liu J; Zhou X; Mao X
    J Biol Chem; 2019 Mar; 294(12):4572-4582. PubMed ID: 30718275
    [TBL] [Abstract][Full Text] [Related]  

  • 14. β-catenin is regulated by USP9x and mediates resistance to TRAIL-induced apoptosis in breast cancer.
    Ouyang W; Zhang S; Yang B; Yang C; Zhang J; Zhou F; Xie C
    Oncol Rep; 2016 Feb; 35(2):717-24. PubMed ID: 26717875
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics.
    Chen X; Lu D; Gao J; Zhu H; Zhou Y; Gao D; Zhou H
    J Proteome Res; 2019 Jun; 18(6):2654-2665. PubMed ID: 31059266
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair.
    Yu H; Pak H; Hammond-Martel I; Ghram M; Rodrigue A; Daou S; Barbour H; Corbeil L; Hébert J; Drobetsky E; Masson JY; Di Noia JM; Affar el B
    Proc Natl Acad Sci U S A; 2014 Jan; 111(1):285-90. PubMed ID: 24347639
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RAD6B is a major mediator of triple negative breast cancer cisplatin resistance: Regulation of translesion synthesis/Fanconi anemia crosstalk and BRCA1 independence.
    Haynes B; Gajan A; Nangia-Makker P; Shekhar MP
    Biochim Biophys Acta Mol Basis Dis; 2020 Jan; 1866(1):165561. PubMed ID: 31639439
    [TBL] [Abstract][Full Text] [Related]  

  • 18. USP7 deubiquitinase promotes ubiquitin-dependent DNA damage signaling by stabilizing RNF168.
    Zhu Q; Sharma N; He J; Wani G; Wani AA
    Cell Cycle; 2015; 14(9):1413-25. PubMed ID: 25894431
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Functional and mutational landscapes of BRCA1 for homology-directed repair and therapy resistance.
    Anantha RW; Simhadri S; Foo TK; Miao S; Liu J; Shen Z; Ganesan S; Xia B
    Elife; 2017 Apr; 6():. PubMed ID: 28398198
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deubiquitinase USP9x confers radioresistance through stabilization of Mcl-1.
    Trivigno D; Essmann F; Huber SM; Rudner J
    Neoplasia; 2012 Oct; 14(10):893-904. PubMed ID: 23097624
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.