235 related articles for article (PubMed ID: 31512855)
1. Clarifying the Mechanism of Copper(II) α-(N)-Heterocyclic Thiosemicarbazone Complexes on DNA Topoisomerase IIα and IIβ.
Keck JM; Conner JD; Wilson JT; Jiang X; Lisic EC; Deweese JE
Chem Res Toxicol; 2019 Oct; 32(10):2135-2143. PubMed ID: 31512855
[TBL] [Abstract][Full Text] [Related]
2. Examination of the Impact of Copper(II) α-(N)-Heterocyclic Thiosemicarbazone Complexes on DNA Topoisomerase IIα.
Wilson JT; Jiang X; McGill BC; Lisic EC; Deweese JE
Chem Res Toxicol; 2016 Apr; 29(4):649-58. PubMed ID: 26982206
[TBL] [Abstract][Full Text] [Related]
3. Structural and Metal Ion Effects on Human Topoisomerase IIα Inhibition by α-(N)-Heterocyclic Thiosemicarbazones.
Morris WH; Ngo L; Wilson JT; Medawala W; Brown AR; Conner JD; Fabunmi F; Cashman DJ; Lisic EC; Yu T; Deweese JE; Jiang X
Chem Res Toxicol; 2019 Jan; 32(1):90-99. PubMed ID: 30484632
[TBL] [Abstract][Full Text] [Related]
4. Role of metalation in the topoisomerase IIα inhibition and antiproliferation activity of a series of α-heterocyclic-N4-substituted thiosemicarbazones and their Cu(II) complexes.
Zeglis BM; Divilov V; Lewis JS
J Med Chem; 2011 Apr; 54(7):2391-8. PubMed ID: 21391686
[TBL] [Abstract][Full Text] [Related]
5. HU-331 and Oxidized Cannabidiol Act as Inhibitors of Human Topoisomerase IIα and β.
Wilson JT; Fief CA; Jackson KD; Mercer SL; Deweese JE
Chem Res Toxicol; 2018 Feb; 31(2):137-144. PubMed ID: 29272108
[TBL] [Abstract][Full Text] [Related]
6. Copper(II) complexes with highly water-soluble L- and D-proline-thiosemicarbazone conjugates as potential inhibitors of Topoisomerase IIα.
Bacher F; Enyedy É; Nagy NV; Rockenbauer A; Bognár GM; Trondl R; Novak MS; Klapproth E; Kiss T; Arion VB
Inorg Chem; 2013 Aug; 52(15):8895-908. PubMed ID: 23829568
[TBL] [Abstract][Full Text] [Related]
7. Polyamine-containing etoposide derivatives as poisons of human type II topoisomerases: Differential effects on topoisomerase IIα and IIβ.
Oviatt AA; Kuriappan JA; Minniti E; Vann KR; Onuorah P; Minarini A; De Vivo M; Osheroff N
Bioorg Med Chem Lett; 2018 Sep; 28(17):2961-2968. PubMed ID: 30006062
[TBL] [Abstract][Full Text] [Related]
8. Biological evaluation of novel thiomaltol-based organometallic complexes as topoisomerase IIα inhibitors.
Legina MS; Nogueira JJ; Kandioller W; Jakupec MA; González L; Keppler BK
J Biol Inorg Chem; 2020 May; 25(3):451-465. PubMed ID: 32193613
[TBL] [Abstract][Full Text] [Related]
9. Quinoline-2-carboxaldehyde thiosemicarbazones and their Cu(II) and Ni(II) complexes as topoisomerase IIa inhibitors.
Bisceglie F; Musiari A; Pinelli S; Alinovi R; Menozzi I; Polverini E; Tarasconi P; Tavone M; Pelosi G
J Inorg Biochem; 2015 Nov; 152():10-9. PubMed ID: 26335598
[TBL] [Abstract][Full Text] [Related]
10. A high-throughput fluorescence anisotropy-based assay for human topoisomerase II β-catalyzed ATP-dependent supercoiled DNA relaxation.
Shapiro AB; Austin CA
Anal Biochem; 2014 Mar; 448():23-9. PubMed ID: 24309019
[TBL] [Abstract][Full Text] [Related]
11. Nucleolar translocation of human DNA topoisomerase II by ATP depletion and its disruption by the RNA polymerase I inhibitor BMH-21.
Morotomi-Yano K; Yano KI
Sci Rep; 2021 Nov; 11(1):21533. PubMed ID: 34728715
[TBL] [Abstract][Full Text] [Related]
12. Dexrazoxane may prevent doxorubicin-induced DNA damage via depleting both topoisomerase II isoforms.
Deng S; Yan T; Jendrny C; Nemecek A; Vincetic M; Gödtel-Armbrust U; Wojnowski L
BMC Cancer; 2014 Nov; 14():842. PubMed ID: 25406834
[TBL] [Abstract][Full Text] [Related]
13. Novel xanthone-polyamine conjugates as catalytic inhibitors of human topoisomerase IIα.
Minniti E; Byl JAW; Riccardi L; Sissi C; Rosini M; De Vivo M; Minarini A; Osheroff N
Bioorg Med Chem Lett; 2017 Oct; 27(20):4687-4693. PubMed ID: 28919339
[TBL] [Abstract][Full Text] [Related]
14. Synthesis, computational quantum chemical study, in silico ADMET and molecular docking analysis, in vitro biological evaluation of a novel sulfur heterocyclic thiophene derivative containing 1,2,3-triazole and pyridine moieties as a potential human topoisomerase IIα inhibiting anticancer agent.
Murugavel S; Ravikumar C; Jaabil G; Alagusundaram P
Comput Biol Chem; 2019 Apr; 79():73-82. PubMed ID: 30731361
[TBL] [Abstract][Full Text] [Related]
15. 1,2-Naphthoquinone as a Poison of Human Type II Topoisomerases.
Collins JA; Osheroff N
Chem Res Toxicol; 2021 Apr; 34(4):1082-1090. PubMed ID: 33760604
[TBL] [Abstract][Full Text] [Related]
16. The anticancer thiosemicarbazones Dp44mT and triapine lack inhibitory effects as catalytic inhibitors or poisons of DNA topoisomerase IIα.
Yalowich JC; Wu X; Zhang R; Kanagasabai R; Hornbaker M; Hasinoff BB
Biochem Pharmacol; 2012 Jul; 84(1):52-8. PubMed ID: 22503743
[TBL] [Abstract][Full Text] [Related]
17. Structural organization of the human TOP2A and TOP2B genes.
Lang AJ; Mirski SE; Cummings HJ; Yu Q; Gerlach JH; Cole SP
Gene; 1998 Oct; 221(2):255-66. PubMed ID: 9795238
[TBL] [Abstract][Full Text] [Related]
18. Human topoisomerase IB is a target of a thiosemicarbazone copper(II) complex.
Vutey V; Castelli S; D'Annessa I; Sâmia LB; Souza-Fagundes EM; Beraldo H; Desideri A
Arch Biochem Biophys; 2016 Sep; 606():34-40. PubMed ID: 27431056
[TBL] [Abstract][Full Text] [Related]
19. Oncofetal HMGA2 attenuates genotoxic damage induced by topoisomerase II target compounds through the regulation of local DNA topology.
Ahmed SM; Dröge P
Mol Oncol; 2019 Oct; 13(10):2062-2078. PubMed ID: 31271486
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and enantiopreferential DNA-binding profile of late 3d transition metal R- and S-enantiomeric complexes derived from N,N-bis-(1-benzyl-2-ethoxyethane): Validation of R-enantiomer of copper(II) complex as a human topoisomerase II inhibitor.
Arjmand F; Sharma GC; Muddassir M; Tabassum S
Chirality; 2011 Aug; 23(7):557-67. PubMed ID: 21695735
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]