These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 31517535)

  • 1. New substituted pyrazole derivatives targeting COXs as potential safe anti-inflammatory agents.
    Abdellatif KR; El-Saadi MT; Elzayat SG; Amin NH
    Future Med Chem; 2019 Aug; 11(15):1871-1882. PubMed ID: 31517535
    [No Abstract]   [Full Text] [Related]  

  • 2. Synthesis of Hydroxybenzofuranyl-pyrazolyl and Hydroxyphenyl-pyrazolyl Chalcones and Their Corresponding Pyrazoline Derivatives as COX Inhibitors, Anti-inflammatory and Gastroprotective Agents.
    Ragab FAE; Mohammed EI; Abdel Jaleel GA; Selim AAMAE; Nissan YM
    Chem Pharm Bull (Tokyo); 2020; 68(8):742-752. PubMed ID: 32741915
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis, cyclooxygenase inhibition, anti-inflammatory evaluation and ulcerogenic liability of novel triarylpyrazoline derivatives as selective COX-2 inhibitors.
    Abdellatif KR; Abdelgawad MA; Labib MB; Zidan TH
    Bioorg Med Chem Lett; 2015 Dec; 25(24):5787-91. PubMed ID: 26546221
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis and evaluation of some pyrazolo[3,4-d]pyrimidine derivatives bearing thiazolidinone moiety as anti-inflammatory agents.
    Tageldin GN; Fahmy SM; Ashour HM; Khalil MA; Nassra RA; Labouta IM
    Bioorg Chem; 2018 Oct; 80():164-173. PubMed ID: 29929077
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, molecular docking, and biological evaluation of some novel hydrazones and pyrazole derivatives as anti-inflammatory agents.
    Mohammed KO; Nissan YM
    Chem Biol Drug Des; 2014 Oct; 84(4):473-88. PubMed ID: 24720475
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of new 2-(3-(naphthalen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)thiazole derivatives with potential analgesic and anti-inflammatory activities: In vitro, in vivo and in silico investigations.
    Mohammed ER; Abd-El-Fatah AH; Mohamed AR; Mahrouse MA; Mohammad MA
    Bioorg Chem; 2024 Jun; 147():107372. PubMed ID: 38653152
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and biological evaluation of new nicotinate derivatives as potential anti-inflammatory agents targeting COX-2 enzyme.
    El-Dash Y; Khalil NA; Ahmed EM; Hassan MSA
    Bioorg Chem; 2021 Feb; 107():104610. PubMed ID: 33454504
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, anti-inflammatory, ulcerogenic and cyclooxygenase activities of indenopyrimidine derivatives.
    Undare SS; Valekar NJ; Patravale AA; Jamale DK; Vibhute SS; Walekar LS; Kolekar GB; Deshmukh MB; Anbhule PV
    Bioorg Med Chem Lett; 2016 Feb; 26(3):814-818. PubMed ID: 26764192
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, and biological evaluation of substituted hydrazone and pyrazole derivatives as selective COX-2 inhibitors: Molecular docking study.
    El-Sayed MA; Abdel-Aziz NI; Abdel-Aziz AA; El-Azab AS; Asiri YA; Eltahir KE
    Bioorg Med Chem; 2011 Jun; 19(11):3416-24. PubMed ID: 21570309
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pyrazoles containing thiophene, thienopyrimidine and thienotriazolopyrimidine as COX-2 selective inhibitors: Design, synthesis, in vivo anti-inflammatory activity, docking and in silico chemo-informatic studies.
    El-Shoukrofy MS; Abd El Razik HA; AboulWafa OM; Bayad AE; El-Ashmawy IM
    Bioorg Chem; 2019 Apr; 85():541-557. PubMed ID: 30807897
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, modeling and biological evaluation of some pyrazolo[3,4-d]pyrimidinones and pyrazolo[4,3-e][1,2,4]triazolo[4,3-a]pyrimidinones as anti-inflammatory agents.
    Tageldin GN; Ibrahim TM; Fahmy SM; Ashour HM; Khalil MA; Nassra RA; Labouta IM
    Bioorg Chem; 2019 Sep; 90():102844. PubMed ID: 31229797
    [TBL] [Abstract][Full Text] [Related]  

  • 12. New 1,2,4-triazole/pyrazole hybrids linked to oxime moiety as nitric oxide donor celecoxib analogs: Synthesis, cyclooxygenase inhibition anti-inflammatory, ulcerogenicity, anti-proliferative activities, apoptosis, molecular modeling and nitric oxide release studies.
    Fadaly WAA; Elshaier YAMM; Hassanein EHM; Abdellatif KRA
    Bioorg Chem; 2020 May; 98():103752. PubMed ID: 32197148
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, biological evaluation and docking study of a new series of di-substituted benzoxazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents.
    Kaur A; Pathak DP; Sharma V; Wakode S
    Bioorg Med Chem; 2018 Feb; 26(4):891-902. PubMed ID: 29373271
    [TBL] [Abstract][Full Text] [Related]  

  • 14. COX-1/COX-2 inhibition assays and histopathological study of the new designed anti-inflammatory agent with a pyrazolopyrimidine core.
    Abdelall EKA; Lamie PF; Ahmed AKM; El-Nahass ES
    Bioorg Chem; 2019 May; 86():235-253. PubMed ID: 30716621
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel tetrazole-based selective COX-2 inhibitors: Design, synthesis, anti-inflammatory activity, evaluation of PGE
    Labib MB; Fayez AM; El-Nahass ES; Awadallah M; Halim PA
    Bioorg Chem; 2020 Nov; 104():104308. PubMed ID: 33011534
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel 1,3-diaryl pyrazole derivatives bearing methylsulfonyl moiety: Design, synthesis, molecular docking and dynamics, with dual activities as anti-inflammatory and anticancer agents through selectively targeting COX-2.
    Shaker AMM; Shahin MI; AboulMagd AM; Abdel Aleem SA; Abdel-Rahman HM; Abou El Ella DA
    Bioorg Chem; 2022 Dec; 129():106143. PubMed ID: 36191430
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Screening of curcumin-derived isoxazole, pyrazoles, and pyrimidines for their anti-inflammatory, antinociceptive, and cyclooxygenase-2 inhibition.
    Ahmed M; Qadir MA; Hameed A; Imran M; Muddassar M
    Chem Biol Drug Des; 2018 Jan; 91(1):338-343. PubMed ID: 28741789
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis and evaluation of some pyrazolo[3,4-d]pyrimidines as anti-inflammatory agents.
    Tageldin GN; Fahmy SM; Ashour HM; Khalil MA; Nassra RA; Labouta IM
    Bioorg Chem; 2018 Aug; 78():358-371. PubMed ID: 29627656
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on celecoxib scaffold supported with in vivo anti-inflammatory activity, ulcerogenic liability, ADME profiling and docking study.
    Abdellatif KRA; Abdelall EKA; Elshemy HAH; Philoppes JN; Hassanein EHM; Kahk NM
    Bioorg Chem; 2022 Mar; 120():105627. PubMed ID: 35065465
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of small molecule acting as multitarget inhibitor of colorectal cancer by simultaneous blocking of the key COX-2, 5-LOX and PIM-1 kinase enzymes.
    El-Miligy MMM; Al-Kubeisi AK; El-Zemity SR; Nassra RA; Abu-Serie MM; Hazzaa AA
    Bioorg Chem; 2021 Oct; 115():105171. PubMed ID: 34303896
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.