BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

637 related articles for article (PubMed ID: 31519687)

  • 1. Diminished AHR Signaling Drives Human Acute Myeloid Leukemia Stem Cell Maintenance.
    Ly M; Rentas S; Vujovic A; Wong N; Moreira S; Xu J; Holzapfel N; Bhatia S; Tran D; Minden MD; Draper JS; Hope KJ
    Cancer Res; 2019 Nov; 79(22):5799-5811. PubMed ID: 31519687
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Aryl hydrocarbon receptor (AHR) is a novel druggable pathway controlling malignant progenitor proliferation in chronic myeloid leukemia (CML).
    Gentil M; Hugues P; Desterke C; Telliam G; Sloma I; Souza LEB; Baykal S; Artus J; Griscelli F; Guerci A; Johnson-Ansah H; Foudi A; Bennaceur-Griscelli A; Turhan AG
    PLoS One; 2018; 13(8):e0200923. PubMed ID: 30091999
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Induction of leukemic stem cell differentiation by aryl hydrocarbon receptor agonist and synergy with gilteritinib in FLT3-ITD + acute myeloid leukemia.
    Han H; Shin DY; Kim D; Kim H; Lee C; Koh Y; Hong J; Yoon SS
    Leuk Lymphoma; 2020 Aug; 61(8):1932-1942. PubMed ID: 32374198
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Single-Cell Gene Expression Analyses Reveal Distinct Self-Renewing and Proliferating Subsets in the Leukemia Stem Cell Compartment in Acute Myeloid Leukemia.
    Sachs K; Sarver AL; Noble-Orcutt KE; LaRue RS; Antony ML; Chang D; Lee Y; Navis CM; Hillesheim AL; Nykaza IR; Ha NA; Hansen CJ; Karadag FK; Bergerson RJ; Verneris MR; Meredith MM; Schomaker ML; Linden MA; Myers CL; Largaespada DA; Sachs Z
    Cancer Res; 2020 Feb; 80(3):458-470. PubMed ID: 31784425
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A TIM-3/Gal-9 Autocrine Stimulatory Loop Drives Self-Renewal of Human Myeloid Leukemia Stem Cells and Leukemic Progression.
    Kikushige Y; Miyamoto T; Yuda J; Jabbarzadeh-Tabrizi S; Shima T; Takayanagi S; Niiro H; Yurino A; Miyawaki K; Takenaka K; Iwasaki H; Akashi K
    Cell Stem Cell; 2015 Sep; 17(3):341-52. PubMed ID: 26279267
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Blast cells surviving acute myeloid leukemia induction therapy are in cycle with a signature of FOXM1 activity.
    Williams MS; Basma NJ; Amaral FMR; Wiseman DH; Somervaille TCP
    BMC Cancer; 2021 Oct; 21(1):1153. PubMed ID: 34711181
    [TBL] [Abstract][Full Text] [Related]  

  • 7. GPR84 sustains aberrant β-catenin signaling in leukemic stem cells for maintenance of MLL leukemogenesis.
    Dietrich PA; Yang C; Leung HH; Lynch JR; Gonzales E; Liu B; Haber M; Norris MD; Wang J; Wang JY
    Blood; 2014 Nov; 124(22):3284-94. PubMed ID: 25293777
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of altered growth factor receptor-mediated JAK2 signaling in growth and maintenance of human acute myeloid leukemia stem cells.
    Cook AM; Li L; Ho Y; Lin A; Li L; Stein A; Forman S; Perrotti D; Jove R; Bhatia R
    Blood; 2014 May; 123(18):2826-37. PubMed ID: 24668492
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Single-cell mass cytometry reveals intracellular survival/proliferative signaling in FLT3-ITD-mutated AML stem/progenitor cells.
    Han L; Qiu P; Zeng Z; Jorgensen JL; Mak DH; Burks JK; Schober W; McQueen TJ; Cortes J; Tanner SD; Roboz GJ; Kantarjian HM; Kornblau SM; Guzman ML; Andreeff M; Konopleva M
    Cytometry A; 2015 Apr; 87(4):346-56. PubMed ID: 25598437
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The cell of origin and the leukemia stem cell in acute myeloid leukemia.
    Chopra M; Bohlander SK
    Genes Chromosomes Cancer; 2019 Dec; 58(12):850-858. PubMed ID: 31471945
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MicroRNA-9 promotes proliferation of leukemia cells in adult CD34-positive acute myeloid leukemia with normal karyotype by downregulation of Hes1.
    Tian C; You MJ; Yu Y; Zhu L; Zheng G; Zhang Y
    Tumour Biol; 2016 Jun; 37(6):7461-71. PubMed ID: 26678889
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Multi-kinase Inhibitor Debio 0617B Reduces Maintenance and Self-renewal of Primary Human AML CD34
    Murone M; Radpour R; Attinger A; Chessex AV; Huguenin AL; Schürch CM; Banz Y; Sengupta S; Aguet M; Rigotti S; Bachhav Y; Massière F; Ramachandra M; McAllister A; Riether C
    Mol Cancer Ther; 2017 Aug; 16(8):1497-1510. PubMed ID: 28468777
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression of putative leukemia stem cell targets in genetically-defined acute myeloid leukemia subtypes.
    Yanagisawa B; Perkins B; Karantanos T; Levis M; Ghiaur G; Smith BD; Jones RJ
    Leuk Res; 2020 Dec; 99():106477. PubMed ID: 33220589
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Zeb1 modulates hematopoietic stem cell fates required for suppressing acute myeloid leukemia.
    Almotiri A; Alzahrani H; Menendez-Gonzalez JB; Abdelfattah A; Alotaibi B; Saleh L; Greene A; Georgiou M; Gibbs A; Alsayari A; Taha S; Thomas LA; Shah D; Edkins S; Giles P; Stemmler MP; Brabletz S; Brabletz T; Boyd AS; Siebzehnrubl FA; Rodrigues NP
    J Clin Invest; 2021 Jan; 131(1):. PubMed ID: 33108352
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential niche and Wnt requirements during acute myeloid leukemia progression.
    Lane SW; Wang YJ; Lo Celso C; Ragu C; Bullinger L; Sykes SM; Ferraro F; Shterental S; Lin CP; Gilliland DG; Scadden DT; Armstrong SA; Williams DA
    Blood; 2011 Sep; 118(10):2849-56. PubMed ID: 21765021
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Long noncoding RNA HOTAIR promotes the self-renewal of leukemia stem cells through epigenetic silencing of p15.
    Gao S; Zhou B; Li H; Huang X; Wu Y; Xing C; Yu X; Ji Y
    Exp Hematol; 2018 Nov; 67():32-40.e3. PubMed ID: 30172749
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SYK inhibition targets acute myeloid leukemia stem cells by blocking their oxidative metabolism.
    Polak A; Bialopiotrowicz E; Krzymieniewska B; Wozniak J; Stojak M; Cybulska M; Kaniuga E; Mikula M; Jablonska E; Gorniak P; Noyszewska-Kania M; Szydlowski M; Piechna K; Piwocka K; Bugajski L; Lech-Maranda E; Barankiewicz J; Kolkowska-Lesniak A; Patkowska E; Glodkowska-Mrowka E; Baran N; Juszczynski P
    Cell Death Dis; 2020 Nov; 11(11):956. PubMed ID: 33159047
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CD9, a potential leukemia stem cell marker, regulates drug resistance and leukemia development in acute myeloid leukemia.
    Liu Y; Wang G; Zhang J; Chen X; Xu H; Heng G; Chen J; Zhao Y; Li J; Ni Y; Zhang Y; Shan J; Qian C
    Stem Cell Res Ther; 2021 Jan; 12(1):86. PubMed ID: 33494824
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The role of exosomes in the stemness maintenance and progression of acute myeloid leukemia.
    Li Q; Wang M; Liu L
    Biochem Pharmacol; 2023 Jun; 212():115539. PubMed ID: 37024061
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Autonomous TGFβ signaling induces phenotypic variation in human acute myeloid leukemia.
    Shingai Y; Yokota T; Okuzaki D; Sudo T; Ishibashi T; Doi Y; Ueda T; Ozawa T; Nakai R; Tanimura A; Ichii M; Shibayama H; Kanakura Y; Hosen N
    Stem Cells; 2021 Jun; 39(6):723-736. PubMed ID: 33539590
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.